There are currently 155 active clinical trials seeking participants for Hypertension research studies. The states with the highest number of trials for Hypertension participants are California, Florida, Texas and Ontario.
HTN App for HTN Control and Cardiovascular Health Among African-Americans
NCT06346886
Recruiting
The purpose of this study is to test the hypertension (HTN) app-based intervention to see if it is more effective in improving uncontrolled HTN and HTN self-care among Africian-Americans from baseline to post-intervention (immediate, 3 months and 6 months post-intervention) as compared to the standard of care.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/11/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Hypertension
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Timing of Sodium Intake and Nocturnal Sodium Excretion and Blood Pressure in Obese African Americans
NCT04021355
Recruiting
Experimental data have shown that timing of sodium intake impacts diurnal patterns of sodium excretion. The purpose of this study is to test the hypothesis that the time of day for salt intake impacts (1) blood pressure rhythms and urinary sodium excretion and (2) circadian timing of factors responsible for blood pressure regulation and cardiometabolic health in obese individuals. These studies will address two aims. The first aim will test the hypothesis that limiting high salt intake prior to... Read More
Gender:
ALL
Ages:
Between 25 years and 45 years
Trial Updated:
03/09/2025
Locations: University of Alabama, Birmingham, Alabama
Conditions: Obesity, Hypertension, Circadian Dysregulation, Salt; Excess
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BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
NCT06059638
Recruiting
A prospective, multinational, randomized, double-blind, clinical trial evaluating the safety and effectiveness of a novel atrioventricular interval modulation (AVIM) algorithm downloaded into a dual-chamber Medtronic Astra/Azure pacemaker.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/07/2025
Locations: HonorHealth, Scottsdale, Arizona +47 locations
Conditions: Hypertension, Hypertension, Systolic, Hypertension, Essential
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Contributions to Hypertension With Androgen Deprivation Therapy
NCT05700903
Recruiting
This study plans to learn more about contributors to high blood pressure in men who undergo androgen deprivation therapy (ADT) to treat prostate cancer. Prostate cancer is the most common non-skin cancer in men, affecting approximately 1 in 8 American men and its primary treatment is through the use of ADT. However, ADT increases the likelihood of developing heart disease including high blood pressure. This study will determine if dysfunction of the nervous system and/or kidneys occurs in men un... Read More
Gender:
MALE
Ages:
40 years and above
Trial Updated:
03/06/2025
Locations: UCHealth University of Colorado Hospital, Aurora, Colorado
Conditions: Androgen Deprivation Therapy, Prostate Cancer, Hypertension, Autonomic Dysfunction, Renal Disease
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Social Risk Score, Clinical Decision Support Tool and Closed Loop Referral for Social Risk Screen and Referral
NCT05574699
Recruiting
The overarching goal of this project is to leverage health information technology (HIT) to integrate available digital information on social needs to improve care for racial and ethnic minorities and socially disadvantaged populations with chronic diseases. In the previous phases of this project the investigators developed a social risk score to identify social needs among medically under-served patients with special emphasis on application among African American patients with low income and ch... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/06/2025
Locations: Johns Hopkins GreenSpring Station, Baltimore, Maryland +4 locations
Conditions: Chronic Disease, Diabetes Mellitus, Hypertension, Congestive Heart Failure
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A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients
NCT03626688
Recruiting
Study ROR-PH-301, ADVANCE OUTCOMES, is designed to assess the efficacy and safety of ralinepag when added to pulmonary arterial hypertension (PAH) standard of care or PAH-specific background therapy in subjects with World Health Organization (WHO) Group 1 PAH.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/04/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama +213 locations
Conditions: PAH, Pulmonary Hypertension, Pulmonary Arterial Hypertension, Hypertension, Connective Tissue Diseases, Familial Primary Pulmonary Hypertension, Vascular Diseases, Cardiovascular Diseases, Hypertension, Pulmonary, Lung Diseases, Respiratory Tract Disease
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Sleep Restriction and Parental History of Hypertension
NCT06482814
Recruiting
The purpose of this study is to research the effects of partial sleep deprivation (sleep restriction) in a group of individuals whose parents have high blood pressure compared to a group of individuals whose parents have normal blood pressure.
Gender:
ALL
Ages:
Between 18 years and 35 years
Trial Updated:
03/03/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Hypertension
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Inspiratory Muscle Strength Training for Lowering Blood Pressure and Improving Endothelial Function in Postmenopausal Women: Comparison With "Standard of Care" Aerobic Exercise
NCT05000515
Recruiting
High blood pressure (BP) is the major modifiable risk factor for cardiovascular diseases (CVD) and related health conditions, particularly among postmenopausal (PM) women. In adults age ≥50 years this risk is primarily driven by above-normal systolic BP (SBP ≥120 mmHg), as diastolic BP plateaus, then decreases in older adulthood. Although SBP is lower in premenopausal women vs. age-matched men, SBP reaches, then surpasses men after age 60. As such, \>75% of PM women in the U.S. have above-normal... Read More
Gender:
FEMALE
Ages:
50 years and above
Trial Updated:
02/26/2025
Locations: Integrative Physiology of Aging Laboratory, Boulder, Colorado
Conditions: Aging, Blood Pressure, Endothelial Dysfunction, Hypertension
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A Mobile Health (mHealth) Strategy for Improving Blood Pressure Control Among Adult Hypertensive African Americans
NCT06078540
Recruiting
The purpose of this study is to test the proof-of-concept for adding a novel mHealth application, USeeBP, to the established UChicago Medicine Ambulatory Medicine Remote-Patient Monitoring (UCM-RPM) Hypertension Management Program in a population of African American adults with poorly controlled hypertension.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
02/26/2025
Locations: University of Chicago, Chicago, Illinois
Conditions: Hypertension, Blood Pressure
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Sympathetic Mechanisms in Obesity-Crossover Design
NCT05312892
Recruiting
We will study obese hypertensive subjects in a randomized, crossover study to determine if two weeks sympathetic blockade improves endogenous glucose production. Subjects will be studied on 3 different occasions after two weeks of receiving either placebo, amlodipine (vasodilator arm) or moxonidine (study arm). The order of the studies will be determined using computer-generated randomization. Patients will be blinded as to which treatment they are receiving on each day. An investigator blinded... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
02/23/2025
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Obesity, Hypertension
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Nicotinamide Riboside for Treating Elevated Systolic Blood Pressure and Arterial Stiffness in Middle-aged and Older Adults
NCT03821623
Recruiting
Aging is the primary risk factor for cardiovascular diseases (CVD), the number one cause of death in developed societies. Systolic blood pressure (SBP) increase with age and is a key intermediary factor linking aging to increased CVD risk. The primary mechanisms underlying the age-associated increase in SBP is stiffening of the large elastic arteries, which is mediated by increases in oxidative stress, inflammation, and vascular smooth muscle tone. Regular caloric restriction is effective at low... Read More
Gender:
ALL
Ages:
50 years and above
Trial Updated:
02/19/2025
Locations: Integrative Physiology of Aging Laboratory, Boulder, Colorado
Conditions: Hypertension, Aging
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Community Engagement Alliance Against Disparities
NCT06607341
Recruiting
The Community Engagement Alliance against Disparities - Washington District of Columbia, Maryland, Virginia (CEAL DMV), is a multi-community and multi-university consortium. Through collaboration and shared leadership, the CEAL-DMV the consortium- comprising five institutions: George Washington University, Howard University, Johns Hopkins University, Morgan State University, and the University of Maryland, Baltimore-has established a regional structure for bi-directional community involvement to... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/17/2025
Locations: George Washington University, Milken Institute of Public Health, Washington, District of Columbia +1 locations
Conditions: Diabetes, Pre-diabetes, Hypertension, Overweight and Obesity
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