There are currently 162 active clinical trials seeking participants for Hypertension research studies. The states with the highest number of trials for Hypertension participants are California, Florida, Texas and Ontario.
Project 2: ACHIEVE- HF
NCT05330221
Recruiting
This project is part of the ACHIEVE GREATER (Addressing Cardiometabolic Health Inequities by Early PreVEntion in the GREAT LakEs Region) Center (IRB 100221MP2A), the purpose of which is to reduce cardiometabolic health disparities and downstream Black-White lifespan inequality in two cities: Detroit, Michigan, and Cleveland, Ohio. The ACHIEVE GREATER Center will involve three separate but related projects that aim to mitigate health disparities in risk factor control for three chronic conditions... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/26/2024
Locations: Wayne State University, Detroit, Michigan
Conditions: Heart Failure, Hypertension
Register for Updates
Sympathetic Mechanisms in Obesity-Crossover Design
NCT05312892
Recruiting
We will study obese hypertensive subjects in a randomized, crossover study to determine if two weeks sympathetic blockade improves endogenous glucose production. Subjects will be studied on 3 different occasions after two weeks of receiving either placebo, amlodipine (vasodilator arm) or moxonidine (study arm). The order of the studies will be determined using computer-generated randomization. Patients will be blinded as to which treatment they are receiving on each day. An investigator blinded... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/16/2024
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Obesity, Hypertension
Register for Updates
mGlide RCT: A Clinical Glide Path To Close the Guideline-to-Practice Gap In HTN Management
NCT03612271
Recruiting
Hypertension (HTN) is the most important stroke and cardiovascular disease (CVD) risk factor. Unfortunately, there is substantial under-treatment of HTN. Of the 86 million adults with prevalent HTN in the U.S., 40 million (46%) have inadequately controlled blood pressure (BP). This problem is worse among minority groups. In this study, the investigators demonstrate how mHealth (mobile health technology) can improve HTN control rates in stroke survivors and primary care patients without stroke, b... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
02/16/2024
Locations: Epidemiology Clinical Research Center, Minneapolis, Minnesota
Conditions: Hypertension
Register for Updates
Church-based Intervention to Improve Blood Pressure in African Americans
NCT05220332
Recruiting
This is a 12-month behavioral cluster-randomized trial testing a church-based intervention to reduce blood pressure in African Americans with uncontrolled blood pressure.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/15/2024
Locations: Rush University Medical Center, Chicago, Illinois
Conditions: Hypertension
Register for Updates
Assessing the Efficacy of Targeted Home Visits in the Management of Chronic Conditions
NCT05168605
Recruiting
The purpose of study is to evaluate whether home visit programs are an effective method for HTN and T2DM management as compared to standard of care clinic visits.
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
02/12/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Hypertension, Type 2 Diabetes
Register for Updates
ASPIRE: Adapting Self-Blood Pressure Monitoring to Reduce Health Disparities
NCT06175793
Recruiting
The goal of this study is to implement a pilot focusing on developing training manuals and materials for patients and the clinical team to ensure our intervention is delivered consistently and systematically for each patient.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
02/09/2024
Locations: ADMG Oak Lawn IM Clinci, Oak Lawn, Illinois
Conditions: Hypertension
Register for Updates
Imaging the Pathogenesis of Cerebral Small Vessel Disease
NCT05703386
Recruiting
Cerebral small vessel disease (CSVD) can lead to vascular cognitive impairment and dementia (VCID). The hallmark of CSVD is the appearance and progression of white matter hyperintensities (WMH) on MRI. The goal of this study it to recruit and follow individuals at risk for WMH progression and use serial MRI scanning to gain insights into the pathogenesis of CSVD.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/06/2024
Locations: Kennedy Krieger Institute, Baltimore, Maryland
Conditions: Ischemic Stroke, Hypertension, Hyperlipidemias, Diabetes
Register for Updates
ReNEW Clinic Cohort Study
NCT03816462
Recruiting
This is an ongoing, prospective cohort study of children and young adults who are evaluated in the Reversing the Negative Effects of Weight on the Heart (ReNEW) Clinic at Johns Hopkins University. Demographic and clinical data of patients who agree to participate are obtained via chart review and entered into a longitudinal clinic registry.
Gender:
All
Ages:
22 years and below
Trial Updated:
01/31/2024
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Hypertension, Prehypertension, Obesity, Overweight, Left Ventricular Hypertrophy, Elevated Blood Pressure
Register for Updates
Metabolic Effects of Angiotensin-(1-7)
NCT02646475
Recruiting
The overall purpose of this study is to learn more about the metabolic effects of angiotensin-(1-7) in the insulin resistant state associated with obesity. Pharmacologic approaches to increase angiotensin-(1-7) levels or its actions are currently in development for treatment of metabolic-related diseases such as obesity and type II diabetes, based on findings from animal studies. It is unclear if this peptide contributes to the regulation of metabolism in humans. The investigators will test if a... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
01/30/2024
Locations: Vanderbilt University School of Medicine, Nashville, Tennessee
Conditions: Obesity, Insulin Resistance, Hypertension, Metabolic Cardiovascular Syndrome
Register for Updates
Mitochondria Oxidative Stress and Vascular Health Study
NCT05561556
Recruiting
Cardiovascular diseases (CVDs) are the number one cause of death in America and most of the post-industrial world. Hypertension is a leading risk factor for CVDs including stroke, myocardial infarction, and heart failure. Black Americans suffer from the highest rates of hypertension of any racial/ethnic group in America, among the highest in the world. There are also well-documented racial disparities in vascular dysfunction (e.g., endothelial dysfunction, arterial stiffening). Thus, racial disp... Read More
Gender:
All
Ages:
Between 45 years and 75 years
Trial Updated:
01/29/2024
Locations: Auburn University, Auburn, Alabama
Conditions: Cardiovascular Diseases, Hypertension, Racism, Vascular Diseases
Register for Updates
Impact of Intensive Treatment of SBP on Brain Perfusion, Amyloid, and Tau (IPAT Study)
NCT05331144
Recruiting
The purpose of this study is to determine if intensive lowering of systolic blood pressure (SBP), using FDA approved medications (antihypertensive), reduces Alzheimer's Disease pathology (i.e., excessive brain amyloid and tau protein deposition) in older adults at high risk for memory decline or dementia.
Gender:
All
Ages:
Between 60 years and 85 years
Trial Updated:
01/23/2024
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Cognitively Normal Older Adults, Hypertension, Subjective Cognitive Decline, Family History of Dementia
Register for Updates
An Exercise Intervention to Improve Overall Brain Health
NCT06035094
Recruiting
The goal of this clinical trial is to test the effects of 10 weeks of exercise on overall brain health, reduction in blood pressure, and the number of blood vessels in the back of the eyes in patients with hypertension and have a body mass index ≥ 25 kg/m2. The main question[s] it aims to answer are: To test the effect of moderate vs intensive exercise on Brain Care Score outcomes. To ascertain the differential impact of moderate vs high intensity exercise in reducing hypertension and its downs... Read More
Gender:
All
Ages:
Between 35 years and 65 years
Trial Updated:
01/22/2024
Locations: UAB, Birmingham, Alabama
Conditions: Brain Care Score, Exercise, Hypertension, BMI
Register for Updates