Florida is currently home to 3798 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Blood-Brain Barrier Disruption (BBBD) for Liquid Biopsy in Subjects with GlioBlastoma Brain Tumors
Recruiting
The purpose of this study is to evaluate the safety and efficacy of targeted blood brain barrier disruption with Exablate Model 4000 Type 2.0/2.1 for liquid biopsy in subjects with suspected Glioblastoma brain tumors
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
12/10/2024
Locations: UF Health Shands Hospital, Gainesville, Florida
Conditions: Glioblastoma, Glioma, Liquid Biopsy
Effect of Inspiratory Muscle Training on Physiological Function and Clinical Outcomes After Lung Transplant
Recruiting
The purpose of this research is to study the effect of training the inspiratory muscles (i.e. the muscle that allow you to breath-in) on exercise capacity, quality of life, and short-term clinical outcomes in patients post lung transplant.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/10/2024
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Post-Lung Transplantation Bronchiectasis
Multicenter Symphony IL-6 Monitoring Sepsis ICU Validation Study
Recruiting
The primary objective of this study is to validate a pre-defined IL-6 concentration cutoff that predicts 28-day mortality in patients who are admitted or are intended to be admitted to the ICU diagnosed with sepsis or septic shock.
Gender:
ALL
Ages:
22 years and above
Trial Updated:
12/09/2024
Locations: University of Florida College of Medicine, Gainesville, Florida
Conditions: Sepsis, Septic Shock
Radiotherapy Patient Education with Virtual Reality
Recruiting
The purpose of this research study is to investigate the impact of virtual reality experiences on individuals undergoing radiotherapy, aiming to assess whether this immersive technology can reduce anxiety and enhance patient overall treatment satisfaction. By comparing different virtual reality techniques and a standard informational video, the study seeks to identify optimal strategies for leveraging virtual reality to improve the patient experience during radiotherapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/09/2024
Locations: University of Miami, Miami, Florida
Conditions: Anxiety, Cancer
A Phase 2b, Study Evaluating Miricorilant in Adult Patients With Nonalcoholic Steatohepatitis/Metabolic Dysfunction-Associated Steatohepatitis (MONARCH)
Recruiting
A Phase 2b, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy and Safety of Miricorilant in Adult Patients with Nonalcoholic Steatohepatitis (MONARCH)
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
12/09/2024
Locations: Site #452, Boca Raton, Florida
Conditions: Nonalcoholic Steatohepatitis (NASH), Metabolic Dysfunction-associated Steatohepatitis (MASH)
A Study of Oral MBQ-167 in Participants With Advanced Breast Cancer
Recruiting
A Phase 1, open-label, dose-escalation clinical trial of MBQ-167 in participants with advanced Breast Cancer for whom Standard of Care (SOC) has failed or has proven intolerable.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
12/09/2024
Locations: Florida Cancer Specialists / Sarah Cannon Research Institute / SCRI, Sarasota, Florida
Conditions: Breast Cancer, Breast Neoplasm, Breast Cancer Stage IV
Study of DISC-0974 in Participants with Myelofibrosis or Myelodysplastic Syndrome and Anemia
Recruiting
This phase 1b/2a open-label study will assess the safety, tolerability, pharmacokinetics and pharmacodynamics of DISC-0974 as well as categorize the effects on anemia response in subjects with myelofibrosis or myelodysplastic syndrome and anemia.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/09/2024
Locations: Mayo Clinic Jacksonville, Jacksonville, Florida
Conditions: Myelofibrosis; Anemia, Anemia, Myelofibrosis, Myelofibrosis Due to and Following Polycythemia Vera, Primary Myelofibrosis, Post-essential Thrombocythemia Myelofibrosis, Myelodysplastic Syndromes
Biospecimen Biorepository for the Study of ALS, ALS-FTD and Similar Neurodegenerative Disorders
Recruiting
The purpose of this study is to collect CSF and blood samples that can be used in future research studies to identify potential biomarkers in blood and cerebrospinal fluid (CSF) collected in Amyotrophic Lateral Sclerosis (ALS) patients.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/09/2024
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Amyotrophic Lateral Sclerosis
Biomarker and Edema Attenuation in IntraCerebral Hemorrhage (BEACH)
Recruiting
This first-in-patient phase 2a pilot study will assess the safety and tolerability of MW01-6-189WH (hereafter called MW189) in patients with Intracerebral Hemorrhage (ICH).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/09/2024
Locations: Cleveland Clinic Florida, Stuart, Florida
Conditions: Intracerebral Hemorrhage
Opioid-Sparing and Pain-Reducing Properties of Syntocinon: A Dose-Effect Determination
Recruiting
Some research suggests that administration of oxytocin with oxycodone may reduce its abuse liability and improve its ability to reduce pain. In a 6-session laboratory study, the investigators will be evaluating the effects of oxycodone and oxytocin (combined and separately, across sessions) on experimentally-induced pain, subjective effects, decision-making, and activation of different neural substrates.
Gender:
ALL
Ages:
Between 21 years and 45 years
Trial Updated:
12/09/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Pain
Restor. I-131 Upt. + Selpercatinib in RET F-P RAI-R TC
Recruiting
This research is being done to determine the efficacy of selpercatinib to restore radioactive iodine (I-131 NaI) uptake and allow for I-131 treatment in people with RET fusion-positive radioiodine-refractory thyroid cancer. This research study involves the study drug selpercatinib in combination with standard of care treatments, I-131 and thyrotropin alfa (rhTSH).
Gender:
ALL
Ages:
12 years and above
Trial Updated:
12/07/2024
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Thyroid Cancer, Thyroid Carcinoma, Metastatic Thyroid Cancer, Follicular Thyroid Cancer, Unresectable Thyroid Gland Carcinoma, Papillary Thyroid Cancer
A Study to Assess Adverse Events of Fosigotifator (ABBV-CLS-7262) in Adults With Major Depressive Disorder
Recruiting
Major depressive disorder (MDD; depression) is a mood disorder that causes a continued feeling of sadness and loss of interest. It is a common and serious illness that can cause both emotional and physical symptoms such as feelings of sadness, irritability, not being able to focus on activities, tiredness, changes in eating habits, and aches and pains. The main goal of the study is to evaluate how safe and effective fosigotifator is in treating MDD. Fosigotifator (ABBV-CLS-7262) is a new treatm... Read More
Gender:
ALL
Ages:
Between 20 years and 70 years
Trial Updated:
12/06/2024
Locations: Clinical Neuroscience Solutions - Orlando - East South Street /ID# 265060, Orlando, Florida
Conditions: Major Depressive Disorder (MDD)