Florida is currently home to 3745 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Suture Repair vs Mesh Repair for Incisional Hernia
Recruiting
The goal of this randomized controlled trial is to compare the difference in quality of life at one year postoperatively for patients undergoing incisional hernia repair with mesh versus suture repair using modern techniques. The main question it aims to answer are: • Determine if primary suture repair is non-inferior to mesh repair for incisional hernias 2-6cm with respect to quality of life using the HerQLes summary score at one year postoperatively.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/10/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Incisional Hernia
Telehealth in Lewy Body Dementia
Recruiting
Lewy body dementia (LBD) is the 2nd most common neurodegenerative dementia in the US. Optimal care requires an interdisciplinary approach, however often faced barriers include rural residence, limited access to specialists, travel distance, limited awareness of resources, and physical, cognitive, and behavioral impairments making travel to appointments challenging. Delivering interdisciplinary care remotely using video technology has the potential to improve access to care for patients with LBD.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
09/10/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Lewy Body Dementia With Behavioral Disturbance, Lewy Body Parkinson Disease, Lewy Body Disease
Apraxia in Parkinson's Disease Patients With Deep Brain Stimulation
Recruiting
Deep brain stimulation (DBS) of the subthalamic nucleus or globus pallidus internus can improve motor symptoms Parkinson's disease (PD). However, it is not known whether DBS can help reduce the signs and symptoms of the limb-kinetic, ideomotor or ideational apraxia associated with PD or if apraxia can exist as a stimulation induced side effect from DBS therapy. In this study, we look to conduct a pilot study to examine the feasibility of characterizing the prevalence of apraxia in PD patients wi... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
09/10/2024
Locations: UF Health at the University of Florida, Gainesville, Florida
Conditions: Deep Brain Stimulation, Parkinson Disease, Apraxia, Motor
Artificial Intelligence to Measure Adherence to Oral Medication
Recruiting
The aims of this project is to use an artificial intelligence (AI) smartphone app to provide support for medication adherence by patients with first episode psychosis.
Gender:
ALL
Ages:
Between 15 years and 40 years
Trial Updated:
09/10/2024
Locations: Citrus Health, Hialeah, Florida
Conditions: First Episode Psychosis
Disengagement in CSC: Identifying Those at Risk and Addressing Their Needs
Recruiting
Maintaining treatment engagement is critical for first episode psychosis patients to experience gains possible with coordinated specialty care (CSC). This study is designed to identify CSC participants still receiving care but at high risk for disengagement and to intervene to prevent/delay disengagement.
Gender:
ALL
Ages:
Between 15 years and 40 years
Trial Updated:
09/10/2024
Locations: Henderson Behavioral Health, Lauderdale Lakes, Florida
Conditions: First Episode Psychosis
Early-Phase Schizophrenia: Practice-based Research to Improve Outcomes
Recruiting
The goal if the project is to develop a learning health network devoted to the treatment of first episode psychosis.
Gender:
ALL
Ages:
Between 15 years and 40 years
Trial Updated:
09/10/2024
Locations: Henderson Behavioral Health, Lauderdale Lakes, Florida
Conditions: First Episode Psychosis
Biomarkers in Friedreich's Ataxia
Recruiting
The purpose of this project is to characterize measures of cardiac performance and neuromuscular physiology in FA patients using novel techniques, including echocardiography and magnetic resonance imaging (MRI), metabolic exercise testing, and neurophysiological outcomes.
Gender:
ALL
Ages:
Between 8 years and 70 years
Trial Updated:
09/10/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Friedreich's Ataxia
Dysarthria Management for Minor Groups
Recruiting
This study develops and conduct a small-scale clinical trial study in which the linguistic and cultural diversity of the participants is considered. Speech therapy and counseling services are provided to both patients with Parkinson\'s disease and their caregivers.
Gender:
ALL
Ages:
Between 25 years and 85 years
Trial Updated:
09/09/2024
Locations: Florida State University, Tallahassee, Florida
Conditions: Parkinson Disease, Dysarthria
Pilot Trial of the RUBI Program for Autistic Adults
Recruiting
The goal of this clinical trial is to evaluate if a redesigned version of the RUBI parenting intervention can reduce challenging behaviors and improve adaptive skills in autistic adults with co-occurring challenging behaviors. The main questions it aims to answer are: * Is the redesigned RUBI intervention feasible and acceptable for autistic adults and their families? * Does the redesigned RUBI intervention reduce challenging behaviors and enhance the quality of life for autistic adults? * Rese... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/09/2024
Locations: Els for Autism Foundation, Jupiter, Florida
Conditions: Autism Spectrum Disorder, Behavior, Parenting
Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases
Recruiting
This study will assess the safety, efficacy, and feasibility of ⍺/β CD3+ T-cell and CD19+ B-cell depletion in allogeneic stem cell transplantation in patients with acute lymphocytic leukemia (ALL), acute myeloid leukemia (AML), juvenile myelomonocytic leukemia (JMML), high risk myelodysplastic syndrome (MDS), chronic myeloid leukemia (CML) and lymphoma. Subjects will receive an allogeneic stem cell transplant that has been depleted of ⍺/β CD3+ T-cells and CD19+ B-cells using the Miltenyi CliniMA... Read More
Gender:
ALL
Ages:
Between 6 months and 39 years
Trial Updated:
09/09/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Juvenile Myelomonocytic Leukemia, Myelodysplastic Syndromes, Chronic Myeloid Leukemia, Lymphoma, Non-Hodgkin, Lymphoma, Hodgkin
The Diaphragmatic Initiated Ventilatory Assist (DIVA) Trial
Recruiting
DIVA is a pragmatic randomized clinical trial (RCT) to determine: among (P) preterm infants born 23 0/7-28 6/7 weeks gestation undergoing extubation from mechanical ventilation, whether (I) Non-invasive neurally adjusted ventilatory assist (NIV-NAVA) (C) compared with Non-synchronized nasal intermittent positive pressure ventilation (NS-NIPPV), will reduce the incidence of (O) extubation failure within (T) 5 days (120 hours) of extubation.
Gender:
ALL
Ages:
Between 0 days and 9 weeks
Trial Updated:
09/09/2024
Locations: Joe DiMaggio Children's Hospital, Hollywood, Florida
Conditions: Extubation Failure, Bronchopulmonary Dysplasia, Death
Pharmacokinetics and Safety of Epidiferphane and Taxanes in Breast Cancer Patients
Recruiting
Patients with breast cancer are commonly treated with taxane chemotherapy. Some very common side effects of taxanes, such as anemia and peripheral neuropathy, are often as not well addressed during treatment, resulting in dose reductions, dose delays and early discontinuation (collectively called relative dose intensity) of these chemotherapy agents in 15-80 % of patients on these drugs. This reduction in relative dose intensity (RDI) results in worse clinical outcomes such as progression free a... Read More
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
09/09/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Breast Cancer