Florida is currently home to 3730 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Evaluation of an Adolescent Pregnancy Prevention Program; Relationship Smarts+ With Lessons From Mind Matters
Recruiting
The goal of this randomized control trial (RCT) is to assess an innovative adolescent pregnancy prevention program among youth that are at the highest risk of adolescent pregnancy, to prevent pregnancy and Sexually Transmitted Infections (STIs), including HIV/AIDS in the greater Miami area in Florida. The primary research question it aims to answer is: (RQ1a): What is the effect of adding 4.5 hours of Mind Matters trauma-coping skills curriculum to the Relationship Smarts Plus curriculum, on ra... Read More
Gender:
ALL
Ages:
All
Trial Updated:
12/07/2023
Locations: Trinity Church Inc, Miami Gardens, Florida
Conditions: Teen Pregnancy, Contraception Behavior, Sexually Transmitted Diseases, Reproductive Health, Sexual Risk Behavior
Evaluation of the Effectiveness of Nail Genesis DLSO Product for Onychomycosis
Recruiting
This is a Pre-IDE, prospective, multicenter, randomized, parallel-group, double-blind, vehicle- controlled study to evaluate safety and effectiveness of Nail Genesis DLSO Product for the treatment of DLSO compared with vehicle in infected great toenails in a total of 338 males and non-pregnant, non-lactating, females between 18 and 65 years of age (inclusive). Subjects will be randomized in a 2:1 ratio to receive either Nail Genesis DLSO Product or vehicle. Subject eligibility will be determine... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/06/2023
Locations: Doctors Research Network, South Miami, Florida
Conditions: Distal Lateral Subungual Onychomycosis, Onychomycosis
Management of Antiplatelet Regimen During Surgical Procedures
Recruiting
There are key differences today in clinical practice regarding perioperative management of post-PCI patients on DAPT undergoing NCS. Moreover, there are significant differences between bridging agents, and improved safety of current-generation DES. Given the significant limitations of current studies a well-designed registry to study current U.S. practice patterns and the bleeding or ischemic risks associated with the various perioperative DAPT management strategies including bridging and no bri... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/05/2023
Locations: University of Florida, Jacksonville, Florida
Conditions: Cardiac Surgery, Surgery, Percutaneous Coronary Intervention, Surgery--Complications
Mindfulness Training in Adolescents With Type 1 Diabetes
Recruiting
Creation of an adaptation of a mindfulness-based stress reduction mobile health application specifically designed for adolescents living with Type 1 diabetes. Aim to determine whether daily mindfulness improves anxiety symptoms in adolescents with Type 1 diabetes.
Gender:
ALL
Ages:
Between 12 years and 19 years
Trial Updated:
11/30/2023
Locations: University of South Florida College of Nursing, Tampa, Florida
Conditions: Anxiety, Type 1 Diabetes, Quality of Life
Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C Melanoma Patients
Recruiting
The trial aims to evaluate the efficacy of Daromun neoadjuvant treatment followed by surgery and adjuvant therapy to improve in a statistically significant manner the recurrence-free survival (RFS) of Stage IIIB/C melanoma patients with respect to the standard of care (surgery and adjuvant therapy).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/29/2023
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Melanoma Stage IIIB/C
A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE)
Recruiting
A 52-Week, Multi-center, Open-label, Active Treatment Extension Study to Evaluate Safety and Tolerability of Once Daily, Oral Administration of Resmetirom (MGL-3196)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/28/2023
Locations: Excel Medical Clinical Trials, Boca Raton, Florida
Conditions: Non-Alcoholic Fatty Liver Disease
The Role of Gut Microbiota in Heart Failure and Pre-Heart Failure With Preserved Ejection Fraction
Recruiting
Gut microbiota play an important role in normal cardiovascular function and pathophysiology of cardiovascular diseases. Patients with heart failure (HF) have substantial hemodynamic changes which lead to intestinal hypoperfusion and congestion and eventually change gut morphology, permeability, function and composition of gut microbiota and cause translocation of microbial and endotoxins into the blood stream. Additionally, metabolites derived from gut microbiota modulate the pathophysiology of... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/28/2023
Locations: Cardiovascular Clinic at UF Health, Gainesville, Florida
Conditions: Heart Failure
Treatment With Endovascular Intervention for STroke Patients With Existing Disability
Recruiting
TESTED will compare the risks and benefits of endovascular thrombectomy (EVT) to medical management (no EVT) in ischemic stroke patients who have a blockage in one of the large blood vessels in the brain and have a moderate-to-severe disability prior to their stroke.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/27/2023
Locations: University of Miami, Miami, Florida
Conditions: Stroke, Stroke, Acute, Stroke, Ischemic
Pediatric Vasculitis Initiative
Recruiting
Childhood chronic vasculitis describes a group of rare life-threatening diseases that have in common inflammation of blood vessels in vital organs such as kidneys, lungs and brain. Most knowledge about them comes from adult patients. Severe disease requires aggressive life-saving treatments with steroids and some cancer drugs which can themselves cause damage, and increase risks of cancer and severe infections. Conversely, milder disease can be treated with less toxic drugs. Different classifica... Read More
Gender:
ALL
Ages:
20 years and below
Trial Updated:
11/27/2023
Locations: University of Florida, Gainesville, Florida
Conditions: Wegeners Granulomatosis (Granulomatosis With Polyangiitis), Microscopic Polyangiitis, Polyarteritis Nodosa, Takayasu Arteritis, Primary CNS Vasculitis, Unclassified Vasculitis, Eosinophilic Granulomatosis With Polyangiitis
Evaluation of SPH3127 in Patients With Mild-to-Moderate Ulcerative Colitis
Recruiting
SPH3127-US-01 is a multi-center, randomized, double-blind, placebo-controlled study to evaluate the safety, pharmacokinetics, and preliminary efficacy of SPH3127 for the treatment of mild-to-moderate ulcerative colitis.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
11/24/2023
Locations: Clinical Research of West Florida, Clearwater, Florida
Conditions: Ulcerative Colitis
ExoLuminate Study for Early Detection of Pancreatic Cancer
Recruiting
ExoLuminate is a nationally-enrolling registry study designed for earlier detection of cancer in patients at elevated risk or clinically-suspicious for pancreatic ductal adenocarcinoma (PDAC). Those with elevated risk for PDAC can include individuals with intraductal papillary mucinous neoplasms, family history of pancreatic cancer, germline mutations in genes known to be associated with cancer, and a personal or family history of pancreatitis. The goal of the study is to compare the performan... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/22/2023
Locations: University of Florida, Gainesville, Florida
Conditions: Pancreas Cancer, Exosomes, Extracellular Vesicles, Pancreatic Neoplasms
Cardiac Performance System Data Collection Study
Recruiting
Non-significant risk device study to conduct evaluation of the performance of new device for monitoring of cardiac function (based on previous iterations 510(k) 173156)
Gender:
ALL
Ages:
22 years and above
Trial Updated:
11/20/2023
Locations: Orlando Health, Orlando, Florida
Conditions: Cardiac Disease