Maryland is currently home to 2684 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Baltimore, Bethesda, Rockville and Annapolis. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Surgical Resection of Synchronous Pulmonary or Hepatic Oligometastatic Pancreatic Ductal Adenocarcinoma
NCT06122480
Recruiting
Surgical Resection of Synchronous Pulmonary or Hepatic Oligometastatic Pancreatic Ductal Adenocarcinoma (PHOLIPANC). This is an interventional, open-label, non-randomised, single-arm phase II clinical trial. Eligible patients with hepatic or pulmonary oligometastatic adenocarcinoma of the pancreas must have received neoadjuvant FOLFIRINOX chemotherapy in cycles of 14 days, or other clinically indicated alternative. FOLFIRINOX is not a study treatment.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
06/07/2024
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Pancreatic Ductal Adenocarcinoma, Oligometastatic Disease
Register for Updates
Coronary Microvascular Disease (CMD) Registry
NCT05960474
Recruiting
The purpose of this project is to provide appropriate administrative and technical supports for the warehousing and use of a database of patients with coronary microvascular disease (CMD). This protocol will outline the process for identification and capture of data, storage, as well as data use and sharing internally and externally for research purposes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/06/2024
Locations: MedStar Southern Maryland, Clinton, Maryland
Conditions: Coronary Microvascular Dysfunction
Register for Updates
Modifying Adiposity Through Behavioral Strategies to Improve COVID-19 Rehabilitation
NCT05880108
Recruiting
The research in this VA Merit will examine the effects of obesity and Post-COVID Conditions (PCC) on physical functioning, health-related quality of life, and adipose tissue inflammatory and cellular senescence profiles in older Veterans. Further, it will evaluate whether a weight loss intervention, including dietary modification and exercise, in obese Veterans with and without PCC will reduce systemic and adipose tissue inflammation and senescence and promote PCC recovery.
Gender:
ALL
Ages:
Between 55 years and 80 years
Trial Updated:
06/06/2024
Locations: Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD, Baltimore, Maryland
Conditions: Post-COVID Conditions, Obesity
Register for Updates
Medication Adherence in Patients With Sarcoidosis
NCT05438095
Recruiting
The goal of the study is to look at the relationship between how individuals with Sarcoidosis take the sarcoidosis medicines and how it affects the disease, to evaluate any factors that may make individuals not want to take the medicines, and to develop and refine ways to help support individuals with Sarcoidosis especially when it comes to the medicines. The overall hypothesis is higher medication adherence will be associated with better clinical outcomes in sarcoidosis. The investigators will... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/06/2024
Locations: Johns Hopkins Bayview Asthma and Allergy Center, Baltimore, Maryland
Conditions: Medication Adherence, Sarcoidosis
Register for Updates
Roflumilast or Azithromycin to Prevent COPD Exacerbations (RELIANCE)
NCT04069312
Recruiting
A multi-center, randomized, 72-month, parallel- group, non-inferiority, phase III study to compare the effectiveness of roflumilast (Daliresp, 500 mcg quaque die (QD) or alternate regimen) therapy versus azithromycin (250 mg QD, 500 mg QD three times per week, or alternate regimen) to prevent hospitalization or death in a patients at high risk for COPD exacerbations.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
06/06/2024
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Chronic Obstructive Pulmonary Disease Severe, Chronic Bronchitis
Register for Updates
Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney)
NCT06263426
Recruiting
This research is being done to better understand rejection in transplant recipients with HIV who receive kidneys from donors with vs without HIV.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/05/2024
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Hiv
Register for Updates
Neural Mechanisms of Immersive Virtual Reality in Chronic Pain (VR TMD EEG)
NCT06214923
Recruiting
This project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia. The potential of developing new non-pharmacological premises for low-risk interventions for pain management is high.
Gender:
ALL
Ages:
Between 18 years and 88 years
Trial Updated:
06/05/2024
Locations: Luana Colloca, Baltimore, Maryland
Conditions: Pain, Virtual Reality, Placebo, Temporomandibular Disorder
Register for Updates
Chemosensory Dysfunction and Recovery in Endoscopic Endonasal Skull Base Surgery
NCT05912881
Recruiting
The investigators hypothesize that patients undergoing endoscopic endonasal skull base surgery experience clinically meaningful and modifiable disruptions in postoperative chemosensory function and quality of life, and the investigators further hypothesize that olfactory training in the postoperative period may significantly hasten normalization of patients' chemosensory perturbations. This tailored prospective study seeks to fulfill a significant gap in the understanding of the characteristics,... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/05/2024
Locations: Johns Hopkins Medicine, Baltimore, Maryland
Conditions: Anosmia, Skull Base Neoplasms
Register for Updates
Hands and Hearts Together
NCT05834907
Recruiting
Growing evidence demonstrates that secure attachment in childhood predicts children's healthy social, biological, and behavioral functioning, whereas insecure attachment predicts behavior problems and physiological dysregulation; thus, efforts to foster secure attachment are crucial for promoting the healthy development of children and families. This proposal describes a randomized controlled trial (RCT) of an innovative intervention program that can be widely implemented designed to foster chil... Read More
Gender:
ALL
Ages:
8 months and above
Trial Updated:
06/05/2024
Locations: University of Maryland, College Park, College Park, Maryland
Conditions: Parent-Child Relations, Development, Infant, Parenting, Development, Child
Register for Updates
Cognitive Outcomes After Brain Substructure-informed Radiation Planning in Pediatric Patients
NCT05658731
Recruiting
The goal of this trial is to determine whether it is possible to minimize radiation dose to parts of the brain that are important for thinking and learning in children who require radiation to treat their tumor, and if this will help reduce neurocognitive (thinking and learning) impairments in these patients. Patients with newly diagnosed brain or head and neck tumors who are having radiation therapy will have neurocognitive testing and MRI imaging (both research and for regular care) done as p... Read More
Gender:
ALL
Ages:
Between 1 year and 26 years
Trial Updated:
06/05/2024
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Brain Tumor, Head and Neck Cancer
Register for Updates
Feasibility Study on Radiofrequency-Based Selective Electrothermolysis to Investigate Its Effects on Human Skin
NCT05066113
Recruiting
This research is being done to assess the effect of radiofrequency (RF)-based treatment on skin and skin conditions.
Gender:
ALL
Ages:
Between 22 years and 70 years
Trial Updated:
06/05/2024
Locations: Johns Hopkins School of Medicine, Baltimore, Maryland
Conditions: Hidradenitis Suppurativa, Healthy Volunteers
Register for Updates
Proton Radiation Therapy Registry
NCT04376229
Recruiting
The Johns Hopkins Proton Therapy center is establishing a registry to capture the full 3D radiation dosimetry delivered to the patient, baseline clinical data, and disease, toxicity and quality of life outcomes. The goal is to have all patients treated at the proton center to be included in the registry to enable future comparisons of treatment outcomes to assist in understanding which patients can benefit from the use of protons.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
06/05/2024
Locations: Bayview Hospital, Baltimore, Maryland
Conditions: Cancer, Therapy-Related
Register for Updates