Maryland is currently home to 2668 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Baltimore, Bethesda, Rockville and Annapolis. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Connecting Friends and Health Workers to Boost COVID-19 Vaccination in Latino Communities
NCT06128928
Recruiting
The goal of this clinical trial is to find out which approach works better in getting more of the friends and connections of Latino adults get vaccinated against COVID-19. The main questions this study aims to answer are: 1. Can teaching people to use motivational interviewing help more friends and connections of Latino adults get the COVID-19 vaccine compared to just giving information about the vaccine? 2. What are the things that make it easier or harder for Latinos and networks to get the... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/08/2024
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: COVID-19, Vaccine
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Estrogen Supplementation and Bone Health in Women With CF
NCT05704036
Recruiting
The goal of this study is to learn about the role of estrogen and other hormones in bone development in adolescent and young adult women with cystic fibrosis (CF). The study has two main components, an observational study and a feasibility sub-study. The main questions it aims to answer are: * How do different forms of hormonal contraception (e.g. birth control pill or other progesterone only methods) impact bone health? * Is a study of transdermal estradiol (estrogen skin patches) feasible in... Read More
Gender:
FEMALE
Ages:
Between 0 years and 100 years
Trial Updated:
11/08/2024
Locations: Johns Hopkins, Baltimore, Maryland
Conditions: Cystic Fibrosis, Hypoestrogenism
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Tamibarotene Plus Azacitidine in Participants With Newly Diagnosed RARA-positive Higher-Risk Myelodysplastic Syndrome
NCT04797780
Recruiting
This study compares the efficacy of Tamibarotene in combination with azacitidine to azacitidine in combination with placebo in participants who are Retinoic Acid Receptor Alpha (RARA) positive, and newly diagnosed with higher-risk myelodysplastic syndrome (HR-MDS), and who have not received treatment for this diagnosis. The primary goal of the study is to compare the complete remission rate between the two treatment arms.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/08/2024
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Myelodysplastic Syndromes
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Escitalopram and Language Intervention for Subacute Aphasia
NCT03843463
Recruiting
In this project, the investigators will investigate the effects of a selective serotonin reuptake inhibitor (SSRI), escitalopram, on augmenting language therapy effectiveness, as measured by naming untrained pictures and describing pictures, in individuals with aphasia in the acute and subacute post stroke period (i.e., within three months post stroke).
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
11/08/2024
Locations: Johns Hopkins School of Medicine, Baltimore, Maryland
Conditions: Aphasia, Stroke
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Tesamorelin to Improve Functional Outcomes After Peripheral Nerve Injury
NCT03150511
Recruiting
The aim of this clinical trial is to evaluate the efficacy of tesamorelin as a therapy for peripheral nerve injuries. The investigators hypothesize that treatment with tesamorelin will result in faster and more substantial recovery of motor and sensory function following surgical repair of injured peripheral nerves. Patients with upper extremity nerve injuries will be randomly assigned to receive either tesamorelin treatment or no treatment. Assessments for nerve regeneration, muscle function, a... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/08/2024
Locations: Sami Tuffaha, Baltimore, Maryland
Conditions: Peripheral Nerve Injuries
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Cannabidiol (CBD) in Adults With ASD
NCT05015439
Recruiting
There are no FDA approved treatments for use in adults with autism spectrum disorder (ASD), many of whom have distressing anxiety, mood disturbances, sleep problems, and agitation. Some researchers and individuals with ASD have noted that cannabidiol (CBD) is beneficial for those psychiatric problems. This study is to learn more about the effectiveness and safety of CBD in the treatment of psychiatric problems in adults with ASD. The study will last 14 weeks total, during which six weeks partici... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/07/2024
Locations: JHBMC, Baltimore, Maryland
Conditions: Autism Spectrum Disorder
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Patient Specific Talus Spacer Post Approval Study
NCT05364606
Recruiting
Humanitarian Device Exemption Approved Patient Specific Talus Spacer Post Approval Study.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
11/05/2024
Locations: Mercy Institute for Foot & Ankle Reconstruction, Baltimore, Maryland
Conditions: Avascular Necrosis of the Talus
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A Safety and Effectiveness Prospective Blinded Clinical Study to Validate xBar System as Monitoring Tool for Anastomotic Leaks Detection
NCT06168669
Recruiting
Purpose: To validate the safety and effectiveness of xBar monitoring tool for detection of post-operative anastomotic leaks in subjects undergoing rectal/sigmoid resections with anastomosis. The clinical team is blinded to the leak detection of the xBar system.
Gender:
ALL
Ages:
22 years and above
Trial Updated:
11/03/2024
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Colorectal Surgery, Anastomotic Leak
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Multidisciplinary Approach to Reduce Cardiovascular Health Disparities
NCT06168968
Recruiting
The goal of this observational study is to investigate the potential differences in thrombogenicity between black and white patients admitted with atherothrombotic events including acute coronary syndrome, multi-vessel coronary disease, and ischemic stroke. Participants will engage in laboratory testing and health outcome assessments.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/01/2024
Locations: Sinai Hospital of Baltimore, Baltimore, Maryland
Conditions: Acute Coronary Syndrome, Multi Vessel Coronary Artery Disease, Ischemic Stroke
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ONC-392 Plus Lutetium Lu 177 Vipivotide Tetraxetan in Patients With mCRPC
NCT05682443
Recruiting
In this Phase 2 study, mCRPC patients with PSMA positive scans who progressed on prior ARTA and up to 2 lines of taxanes, and are naïve to lutetium Lu 177 vipivotide tetraxetan, will be enrolled. The study is open-label, randomized with active control, multi-center study.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
11/01/2024
Locations: Johns Hopkins University Medical Center - 1627, Baltimore, Maryland
Conditions: Metastatic Castration-resistant Prostate Cancer
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Sildenafil for Early Pulmonary Vascular Disease in Scleroderma
NCT04797286
Recruiting
This is a Phase II randomized, double-blind, placebo-controlled trial of sildenafil in men and women with Scleroderma with mildly elevated pulmonary pressures (SSc-MEP) to determine whether sildenafil may be an effective treatment for SSc-MEP.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/01/2024
Locations: Johns Hopkins, Baltimore, Maryland
Conditions: Scleroderma, Mildly Elevated Pulmonary Pressures
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Glucagon-like Peptide-1 in Type 1 Diabetes
NCT04355832
Recruiting
The hypotheses to be tested in this application is: GLP-1 will acutely protect arterial endothelial function and reduce pro-atherothrombotic and pro-coagulant effects of repeated hypoglycemia in T1DM.
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
11/01/2024
Locations: University of Maryland, Baltimore, Maryland
Conditions: Type1 Diabetes Mellitus
Register for Updates