Maryland is currently home to 2682 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Baltimore, Bethesda, Rockville and Annapolis. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Hydrus® Microstent New Enrollment Post-Approval Study
NCT04553523
Recruiting
The purpose of this post-approval study is to evaluate the rate of Hydrus Microstent malposition and associated clinical sequelae occurring within 24 months post-operation. Qualified subjects will undergo uncomplicated cataract surgery with placement of a monofocal intraocular lens (IOL), followed by implantation of the Hydrus Microstent.
Gender:
ALL
Ages:
45 years and above
Trial Updated:
05/28/2024
Locations: Visionary Eye Doctors, Rockville, Maryland
Conditions: Primary Open Angle Glaucoma
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Remote Delivery of a Mindfulness-based Intervention for Tics
NCT06408662
Recruiting
This research study is being done to compare a mindfulness-based intervention for tics (MBIT) to psychoeducation with relaxation and supportive therapy (PRST) for individuals with Tourette's syndrome or Persistent Tic Disorders (collectively TS). It is the investigator's hope that this information cam be used to improve current treatments for individuals with TS.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/24/2024
Locations: Johns Hopkins University School of Medicine, Baltimore, Maryland
Conditions: Tourette Syndrome, Tourette's Disorder, Chronic Motor Tic Disorder, Chronic Vocal Tic Disorder, Persistent Motor Tic Disorder, Persistent Vocal Tic Disorder, Persistent Tic Disorder, Tic Disorders
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Opioid Use After Laparoscopic Salpingectomy
NCT06434233
Recruiting
The purpose of this study is to evaluate patient-reported post-operative pain scores following minimally invasive tubal sterilization procedures to determine if a multimodal, non-opioid pain control regimen is non-inferior to a pain control regimen including opioids. The study team hypothesizes that with extensive counseling on pain management, multimodal medication use, and expectation with non-opioid methods can effectively eliminate the need for opioid prescriptions after laparoscopic salpin... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/23/2024
Locations: Johns Hopkins Bayview Medical Center, Baltimore, Maryland
Conditions: Opioid Use, Post-operative Pain, Sterility, Female
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Anatomical and Functional Imaging Correlates of Chronic Pain in Cerebral Palsy
NCT05197946
Recruiting
The investigators hope to use MRI biomarkers to identify and characterize sensorimotor network disruption patterns associated with chronic pain and sensory deficits in CP. Investigators will use existing information in the medical record as well as subjective reports from interview, physical exam data, and anatomical and functional MRI data to non-invasively identify brain injury correlates of pain and sensory deficits.
Gender:
ALL
Ages:
8 years and above
Trial Updated:
05/23/2024
Locations: F.M. Kirby Center, Baltimore, Maryland
Conditions: Cerebral Palsy, Chronic Pain
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Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Substance Use Disorders
NCT06434818
Recruiting
The overarching goal of this study phase, Phase II component is to implement Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Substance Use Disorders (EDITOR) device in substance use disorder (SUD) clinics to demonstrate pilot effectiveness for SUD outcomes compared to treatment as usual (TAU) and Computerized Chemosensory-Based Orbitofrontal Networks Training (CBOT) device as active control. The investigators will conduct a multi-site study of 300 adult patients w... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
05/22/2024
Locations: Maryland Treatment Center, Rockville, Maryland
Conditions: Substance Use Disorders, Opioid Use Disorder, Alcohol Use Disorder, Cocaine Use Disorder, Methamphetamine-dependence
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Epidiolex® for Anxiety in Pediatric Epilepsy
NCT05324449
Recruiting
This is a prospective open label study assessing the efficacy and tolerability of pharmaceutical grade cannabidiol--Epidiolex (R), for the treatment of anxiety in pediatric patients with pediatric epilepsy that has been difficult to treat and requires ongoing use of anticonvulsant medication.
Gender:
ALL
Ages:
Between 6 years and 17 years
Trial Updated:
05/22/2024
Locations: Kennedy Krieger Institute, Baltimore, Maryland
Conditions: Anxiety, Epilepsy
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HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide
NCT04904588
Recruiting
This is a prospective, multi-center, Phase II study of hematopoietic cell transplantation (HCT) using human leukocyte antigen (HLA)-mismatched unrelated donors (MMUD) for peripheral blood stem cell transplant in adults and bone marrow stem cell transplant in children. Post-transplant cyclophosphamide (PTCy), tacrolimus and mycophenolate mofetil (MMF) will be used for for graft versus host disease (GVHD) prophylaxis. This trial will study how well this treatment works in patients with hematologic... Read More
Gender:
ALL
Ages:
1 year and above
Trial Updated:
05/22/2024
Locations: University of Maryland Medical Center, Baltimore, Maryland
Conditions: Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, Mixed Phenotype Acute Leukemia, Acute Leukemia, Myelodysplastic Syndromes, Chronic Myelogenous Leukemia, Chronic Lymphocytic Leukemia, Lymphoma
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Neural Mechanisms of Immersive Virtual Reality in Chronic Pain
NCT04851301
Recruiting
This project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia. The potential of developing new non-pharmacological premises for low-risk interventions for pain management is high.
Gender:
ALL
Ages:
Between 18 years and 88 years
Trial Updated:
05/22/2024
Locations: Luana Colloca, Baltimore, Maryland
Conditions: Pain, Virtual Reality, Placebo, Temporomandibular Disorder
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Gut Microbial Metabolites of Apple Polyphenols
NCT06107192
Recruiting
The goal of this controlled feeding trial is to learn about the metabolism of polyphenols, a common class of compounds found in plant-based foods, by the gut microbiome. It will evaluate how differences in gut bacteria across individuals influence metabolism of polyphenols from foods, which may influence health benefits that people receive from different foods.
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
05/20/2024
Locations: Department of Nutrition and Food Science, College Park, Maryland
Conditions: Healthy, Controlled Feeding Trial
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Prophylactic Peptide Vaccine in Advanced ALK+ NSCLC
NCT05950139
Recruiting
The purpose of this study is to evaluate the safety of a cancer peptide vaccine to prevent or delay acquired resistance in advanced ALK+ lung cancer patients currently on ALK targeted therapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/20/2024
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: NSCLC Stage IV, ALK Fusion Protein Expression
Register for Updates
Biodistribution and Pathophysiology Study of 18F-Fluorodeoxysorbitol (18F-FDS) in Diseased Patients
NCT05611892
Recruiting
This study is being performed to see if 18F-FDS is a useful imaging agent for diagnosis of bacterial infections. Position Emission Tomography (PET)/ computed tomography (CT) scans will be obtained after intravenous injection of 18F-FDS to determine biodistribution and pathophysiology in diseased subjects.
Gender:
ALL
Ages:
12 years and above
Trial Updated:
05/20/2024
Locations: Johns Hopkins Medical Institutions, Baltimore, Maryland
Conditions: Enterobacterial Infections, Oncologic Disease, Inflammatory Disease, Invasive Fungal Infections
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PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes
NCT05390892
Recruiting
PRECIDENTD is a randomized, open label, pragmatic clinical trial designed to compare rates of the total number of cardiovascular, kidney, and death events among two alternative treatments for patients with type 2 diabetes (T2D) and either established atherosclerotic cardiovascular disease (ASCVD) or at high risk for ASCVD. To accomplish this objective, we will randomly assign 6,000 patients with established T2D and ASCVD or high-risk for ASCVD in a 1:1 allocation to sodium-glucose cotransporter-... Read More
Gender:
ALL
Ages:
Between 40 years and 80 years
Trial Updated:
05/20/2024
Locations: Johns Hopkins School of Medicine, Baltimore, Maryland
Conditions: Type2Diabetes, ASCVD
Register for Updates