Maryland is currently home to 2679 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Baltimore, Bethesda, Rockville and Annapolis. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Paclitaxel, Pembrolizumab and Olaparib in Previously Treated Advanced Gastric Adenocarcinoma
NCT04209686
Recruiting
The purpose of this study is to evaluate the safety and clinical activity of paclitaxel plus olaparib and pembrolizumab in patients with previously treated advanced Gastric Cancer (GC).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/30/2024
Locations: Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland
Conditions: Advanced Gastric Adenocarcinoma
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Treatment of Refractory BK Infections With Related Donor BK Specific Cytotoxic T-cells (CTLs)
NCT04197596
Recruiting
BK cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be safe and effective in decreasing specific viral load in children, adolescents and young adults (CAYA) with refractory BK infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT) or with primary immunodeficiencies (PID).
Gender:
ALL
Ages:
Between 1 month and 79 years
Trial Updated:
05/30/2024
Locations: Johns Hopkins, Baltimore, Maryland
Conditions: Viral Infection, Primary Immune Deficiency Disorder
Register for Updates
Johns Hopkins Breast Cancer Program Longitudinal Repository
NCT01937039
Recruiting
The Breast Cancer Program Longitudinal Repository (BCPLR) is being established to fulfill the research mission of the Breast Cancer Program at Johns Hopkins and to serve investigators affiliated with it - to develop a repository of specimens with corresponding characteristics from patients seen in the breast care and cancer clinics.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/30/2024
Locations: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland
Conditions: Breast Cancer, Benign Breast Disease
Register for Updates
Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer
NCT01766297
Recruiting
The purpose of this research study is to compare the effects (good and bad) on women and their cancer using proton radiation therapy. This study is being done to see if proton radiation therapy will prove to be beneficial for women with early stage breast cancer. A clinical study is necessary to compare the results (good or bad) of proton radiation therapy.
Gender:
FEMALE
Ages:
50 years and above
Trial Updated:
05/30/2024
Locations: Maryland Proton Treatment Center, Baltimore, Maryland
Conditions: Breast Cancer, Breast Neoplasm, Breast Tumor, Cancer of the Breast
Register for Updates
Registry Study for Radiation Therapy Outcomes
NCT01255748
Recruiting
The purpose of this research study is to collect and analyze information from patients being treated with various forms of radiation therapy.
Gender:
ALL
Ages:
All
Trial Updated:
05/30/2024
Locations: Maryland Proton Treatment Center, Baltimore, Maryland
Conditions: Neoplasms
Register for Updates
DMID 21-0041; Influenza CVD 59000
NCT05666245
Recruiting
The primary objective of EMIT-2 is to use a randomized controlled trial (RCT) design to implement interventions which are known to reduce inhalation (airborne) transmission, so that the contribution of transmission by route of aerosols for influenza may be identified.
Gender:
ALL
Ages:
Between 18 years and 59 years
Trial Updated:
05/29/2024
Locations: University of Maryland, Baltimore, University of Maryland School of Medicine, Center for Vaccine Development and Global Health, Baltimore, Maryland
Conditions: Influenza
Register for Updates
Subscap Reverse Shoulder Arthroplasty
NCT05344898
Recruiting
The subscapularis is part of the rotator cuff and is release as part of a reverse shoulder replacement. The decision to repair this tendon is controversial. This research is being done to help determine if rotator cuff repair improves or hinders shoulder replacement. A worrisome but rare complication after shoulder replacement is dislocation. Rotator cuff repair may help reduce this risk. The repair may hinder some of the range of motion afterwards or could help with internal rotation strength.... Read More
Gender:
ALL
Ages:
Between 18 years and 95 years
Trial Updated:
05/29/2024
Locations: University of Maryland School of Medicine, Baltimore, Maryland
Conditions: Shoulder Injuries, Rotator Cuff Injuries
Register for Updates
Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V
NCT05268289
Recruiting
The overall purpose of this two-part study is to evaluate the efficacy, safety and tolerability of iptacopan (LNP023) in addition to standard of care treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/29/2024
Locations: Novartis Investigative Site, Baltimore, Maryland
Conditions: Lupus Nephritis
Register for Updates
Study of Anti-CD33 Chimeric Antigen Receptor-Expressing T Cells (CD33CART) in Children and Young Adults With Relapsed/Refractory Acute Myeloid Leukemia
NCT03971799
Recruiting
This phase 1/2 trial aims to determine the safety and feasibility of antiCD33 chimeric antigen receptor (CAR) expressing T cells (CD33CART) in children and adolescents/young adults (AYAs) with relapsed/refractory acute myeloid leukemia (AML). The trial will be done in two phases: Phase 1 will determine the maximum tolerated dose of CD33CART cells using a 3+3 trial design, with dose-escalation for autologous products separated from dose-escalation for an allogeneic arm. Phase 2 is an expansion ph... Read More
Gender:
ALL
Ages:
Between 1 year and 35 years
Trial Updated:
05/29/2024
Locations: National Cancer Institute - NIH, Bethesda, Maryland
Conditions: Acute Myelogenous Leukemia
Register for Updates
Effects of Psilocybin in Obsessive Compulsive Disorder
NCT05546658
Recruiting
This study will test the feasibility, safety, and evidence for efficacy of psilocybin administration in participants with obsessive compulsive disorder (OCD). This will serve as a preliminary proof of concept study for future larger studies aimed to investigate the utility, cognitive mechanisms, and neural correlates of this intervention.
Gender:
ALL
Ages:
Between 21 years and 70 years
Trial Updated:
05/28/2024
Locations: Johns Hopkins University School of Medicine, Baltimore, Maryland
Conditions: Obsessive-Compulsive Disorder
Register for Updates
Parkinson's Foundation PD GENEration Genetic Registry
NCT04994015
Recruiting
Development of a central repository for PD-related genomic data for future research.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/28/2024
Locations: Johns Hopkins, Baltimore, Maryland
Conditions: Parkinson's Disease
Register for Updates
Hydrus® Microstent New Enrollment Post-Approval Study
NCT04553523
Recruiting
The purpose of this post-approval study is to evaluate the rate of Hydrus Microstent malposition and associated clinical sequelae occurring within 24 months post-operation. Qualified subjects will undergo uncomplicated cataract surgery with placement of a monofocal intraocular lens (IOL), followed by implantation of the Hydrus Microstent.
Gender:
ALL
Ages:
45 years and above
Trial Updated:
05/28/2024
Locations: Visionary Eye Doctors, Rockville, Maryland
Conditions: Primary Open Angle Glaucoma
Register for Updates