Maryland is currently home to 2746 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Baltimore, Bethesda, Rockville and Annapolis. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Transnasal Induction of Normothermia for Neurogenic Fever
NCT06038513
Recruiting
The objective of this study is to evaluate the efficacy of the COOLSTAT® Transnasal Thermal Regulating Device in reducing temperature in a population of febrile subjects who meet the inclusion/exclusion criteria.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
11/29/2023
Locations: University of Maryland Medical Center, Baltimore, Maryland
Conditions: Stroke, Ischemic, Stroke Hemorrhagic, Seizures, Metabolic Encephalopathy
Register for Updates
Neuroplasticity in Auditory Aging_Project 2 Aims 1 and 2
NCT03475043
Recruiting
Millions of elderly adults in the USA have age related hearing loss (ARHL), a malady that affects half of adults 60-69 years, and the majority of older adults. This hearing loss not only impacts communication and functional ability, but also is strongly associated with cognitive decline and decreased quality of life. This project aims to develop effective strategies to compensate and reverse this process through a deeper understanding of plasticity and adaptive auditory function, and how to enga... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
11/29/2023
Locations: University of Maryland, College Park, Maryland
Conditions: Auditory Perceptual Disorders, Aging Problems
Register for Updates
Ivabradine for Long-Term Effects of COVID-19 With POTS Cohort
NCT05481177
Recruiting
The purpose of the study is three-fold. The primary aim is to identify the proportion of Long-Haul COVID (LHC) and non-LHC volunteers with relevant symptoms actually have postural orthostatic tachycardia syndrome (POTS). The second is to determine benefit of ivabradine treatment. Ivabradine is a drug approved to treat tachycardia in persons with heart failure. The third is to characterize risk factors and outcomes among volunteers with and without LHC. This will include comparison with COVID-19-... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
11/27/2023
Locations: Uniformed Services University, Bethesda, Maryland
Conditions: Postural Orthostatic Tachycardia Syndrome, Long Haul COVID
Register for Updates
Study of HQP1351 in Subjects With Refractory CML and Ph+ ALL
NCT04260022
Recruiting
A multi-center, open-label, randomized, phase Ib study to evaluate the pharmacokinetics (PK) of HQP1351 and to determine the recommended phase 2 dose (RP2D) of HQP1351 in subjects with CML chronic phase (CP), accelerated phase (AP), or blast phase (BP) or with Ph+ ALL, who have experienced resistance or intolerance to at least two tyrosine kinase inhibitors (TKIs) or in subjects with Ph+ B-cell precursor (BCP) ALL or lymphoid blast phase CML (CML LBP), who have experienced resistance or intolera... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/27/2023
Locations: University of Maryland, Baltimore, Maryland
Conditions: Leukemia, Myeloid, Chronic, Myeloid Leukemia, Chronic Myeloid Leukemia, Philadelphia Positive Acute Lymphoblastic Leukemia, B Cell Precursor Type Acute Leukemia
Register for Updates
The Youth Opioid Recovery Support (YORS) Intervention
NCT04173416
Recruiting
Youth are disproportionately affected by the current opioid crisis with catastrophic consequences, and young adults with opioid use disorder (OUD) often struggle with adherence to relapse prevention medications. The Youth Opioid Recovery Support (YORS) model is a promising, innovative, wrap-around approach that addresses barriers to medication adherence and treatment engagement in an effort to improve public health outcomes in this vulnerable young adult population. This study seeks to refine th... Read More
Gender:
All
Ages:
Between 18 years and 28 years
Trial Updated:
11/20/2023
Locations: Mountain Manor Treatment Center, Baltimore, Maryland
Conditions: Opioid-use Disorder, Medication Adherence
Register for Updates
Prospective Database Registry Study of Scoliosis in Children With Cerebral Palsy
NCT00680264
Recruiting
The purpose of this study is to determine the radiographic and clinical outcomes of Scoliosis surgical and non-operative treatment in patients with Cerebral Palsy.
Gender:
All
Ages:
Between 8 years and 21 years
Trial Updated:
11/20/2023
Locations: Johns Hopkins Medical Institute, Baltimore, Maryland
Conditions: Cerebral Palsy, Scoliosis
Register for Updates
The Pediatric Anesthesia Quality Improvement Project
NCT00674388
Recruiting
The Study is designed to collect information about adverse events that occur in children undergoing anesthesia in participating hospitals. Demographic information will be collected on all anesthetics. An analysis of each adverse event will be performed and entered into the database. From this information we will devise strategies to prevent these adverse events.
Gender:
All
Ages:
21 years and below
Trial Updated:
11/20/2023
Locations: Johns Hopkins Childrens Center, Baltimore, Maryland
Conditions: Surgery, Anesthesia, Children
Register for Updates
Evaluation of the SafeSpace App Intervention
NCT06043596
Recruiting
The goal of this study is to evaluate the impact of SafeSpace Sexual Health App, an innovative sexual health promotion program focused on reducing sexual risk factors and promoting sexual and reproductive health and wellbeing among young people assigned female or intersex at birth, particularly Black and/or Latine youth, LGBTQ+ youth, youth in states with high teen birth rates and youth who live in rural communities. This study utilizes a two-arm randomized control trial design to measure impact... Read More
Gender:
Female
Ages:
Between 14 years and 18 years
Trial Updated:
11/17/2023
Locations: Child Trends, Bethesda, Maryland
Conditions: Health Behavior, Health Care Utilization, Unprotected Sex, Sexually Transmitted Infections
Register for Updates
Use of Virtual and Augmented Reality Devices in Vestibular Physical Therapy for mTBI
NCT05326100
Recruiting
Rapidly evolving virtual reality (VR) and augmented reality (AR) technologies are being incorporated by many large-scale industries, and the medical field is no exception. One area that has gained significant attention in recent years is virtual rehabilitation which allows physical therapists to leverage state-of-the-art immersive virtual environments to uniquely address functional deficits in patients who are unresponsive to conventional treatment techniques. Advanced VR and AR technologies are... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
11/17/2023
Locations: Walter Reed National Military Medical Center (WRNMMC), Bethesda, Maryland
Conditions: MTBI - Mild Traumatic Brain Injury, Dysfunction of Vestibular System
Register for Updates
American Hepato-Pancreato-Biliary Association (AHPBA) Pancreatic Irreversible Electroporation (IRE) Registry
NCT02674100
Recruiting
The purpose of this study is to create a registry to provide insight into treatment selection and treatment outcome of pancreatic IRE in order to develop an evidence base such that physicians can provide the best possible care to patients with pancreatic cancer requiring surgical interventions. The investigators seek a better understanding of the uses of ablation in the treatment of unresectable soft tissue pancreatic tumors and the limitations, concerns and complications that earlier users hav... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/16/2023
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Pancreatic Cancer
Register for Updates
Connect® Lymphoma Disease Registry: A US-Based Prospective Observational Cohort Study
NCT04982471
Recruiting
The Connect® Lymphoma Disease Registry is a US-based, multicenter, prospective observational (non-interventional) cohort study designed to collect real-world, participant-level data longitudinally in participants diagnosed with various subtypes of non-Hodgkin lymphoma (NHL).
Gender:
All
Ages:
18 years and above
Trial Updated:
11/15/2023
Locations: Local Institution - 106, Bethesda, Maryland
Conditions: Lymphoma, Non-Hodgkin, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Follicular
Register for Updates
7-Day Trial of Sucraid for Alleviating CSID Symptoms in Subjects With Low, Moderate, and Normal Sucrase Levels
NCT05480761
Recruiting
This is a Phase 4, U.S. only, multi-center study using a 7-day therapeutic response dose (TRD) of commercial Sucraid® to assess the response of treatment in 1100 symptomatic pediatric (6 months to 17 years old) subjects with low, moderate, and normal sucrase activity determined by a disaccharidase assay via EGD within 1 year of the Screening Visit. This study will also explore the relationship between known genetic CSID mutations and sucrase activities via (EGD) disaccharidase assay (low, modera... Read More
Gender:
All
Ages:
Between 6 months and 17 years
Trial Updated:
11/14/2023
Locations: University of Maryland Baltimore, Baltimore, Maryland
Conditions: Congenital Sucrase-Isomaltase Deficiency, CSID, Sucrase Isomaltase Deficiency
Register for Updates