Maryland is currently home to 2668 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Baltimore, Bethesda, Rockville and Annapolis. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Buprenorphine for Probationers and Parolees: Bridging the Gap Into Treatment
NCT03616236
Recruiting
This five-year study will evaluate the effectiveness of the administration of buprenorphine bridge treatment (BBT) to probationers and parolees compared to treatment as usual (TAU), which consists of referral to a community buprenorphine treatment program.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
03/06/2024
Locations: Division of Parole & Probation, Baltimore, Maryland
Conditions: Opioid Use
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A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)
NCT05442567
Recruiting
The study is an extension of two parent studies (MLN0002-3024 \[NCT04779307\] and MLN0002-3025 \[NCT04779320\]). Participants must have participated in one of the previous studies. The purpose of this study is to collect the long-term safety of vedolizumab in children with UC or CD.
Gender:
ALL
Ages:
2 years and above
Trial Updated:
03/05/2024
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Ulcerative Colitis, Crohn's Disease
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Radiographic and Clinical Evaluation of Surgical Treatment for Cervical Deformity: A Multi-Center Study 2.0
NCT04194996
Recruiting
Multi-center, prospective, non-randomized study to evaluate outcomes of surgically treated patients with adult cervical spinal deformity.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: Johns Hopkins University, Department of Neurological Surgery, Baltimore, Maryland
Conditions: Cervical Deformity
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Complex Adult Deformity Surgery (CADS)
NCT04194138
Recruiting
Evaluate surgical treatment outcomes and identify best practice guidelines for complex adult spinal deformity (ASD) patients, including radiographic and clinical outcomes, surgical and postoperative complications, risk factors for and revision surgery rates, and the role of standard work to improve patient outcomes and reduce surgical and postoperative complications.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: John Hopkins University, Department of Orthopedic Surgery, Baltimore, Maryland
Conditions: Adult Spinal Deformity, Scoliosis, Kyphosis, Sagittal Imbalance
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Cerebral Hemorrhage Risk in Hereditary Hemorrhagic Telangiectasia
NCT01158807
Recruiting
This study is one of the three projects of an NIH Rare Disease Clinical Research Consortium. A "consortium" is a group of centres sharing information and resources to perform research. The consortium research focuses on brain blood vessel malformations in three different rare diseases. The focus of this specific study is on Hemorrhagic Telangiectasia (HHT). HHT is a condition characterized by blood vessel malformations, called telangiectasia and arteriovenous malformations (AVMs), occurring in... Read More
Gender:
ALL
Ages:
All
Trial Updated:
03/04/2024
Locations: Johns Hopkins University School of Medicine, Baltimore, Maryland
Conditions: Hereditary Hemorrhagic Telangiectasia
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Chemotherapy Induced Peripheral Neuropathy Natural History Study (EPIPHANY)
NCT03997981
Recruiting
This is a prospective natural history study of CIPN in approximately 200 participants receiving taxanes (paclitaxel, docetaxel) for breast cancer, bortezomib for multiple myeloma, oxaliplatin-based regimens for colorectal cancer, or vincristine for lymphoma.. Demographic data, medical history, electronic PROs, ClinROs blood biomarkers including NF-L, PGx DNA analyses and Bedside-QST will be assessed at Baseline. The Observation Period will initiate with the first dose of chemotherapy and conclud... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/29/2024
Locations: University of Maryland School of Medicine, Baltimore, Maryland
Conditions: Chemotherapy-induced Peripheral Neuropathy
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Advanced Prediction of Respiratory Depression Episode With the Linshom Continuous Predictive Respiratory Sensor
NCT05804175
Recruiting
Investigators will enroll 320 patients who will undergo non-cardiac surgery, receive supplemental oxygen via face mask, and will be on a continuous pulse oximetry monitor in the Post Anesthesia Care Unit (PACU). The enrollment criteria were adapted from a previous study that showed SpO2 values seriously underestimated the severity of post-operative hypoxemia in patients with and without specific risk factors for hypoxemia. Research personnel will screen and ensure that each subject meets the enr... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/28/2024
Locations: Linshom Medical, Inc., Ellicott City, Maryland
Conditions: Post Surgical Respiratory Failure, Respiratory Complication
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Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort
NCT01574053
Recruiting
Enroll-HD is a longitudinal, observational, multinational study that integrates two former Huntington's disease (HD) registries-REGISTRY in Europe, and COHORT in North America and Australasia-while also expanding to include sites in Latin America. More than 30,000 participants have now enrolled into the study. With annual assessments and no end date, Enroll-HD has built a large and rich database of longitudinal clinical data and biospecimens that form the basis for studies developing tools and b... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/26/2024
Locations: University of Maryland School of Medicine, Baltimore, Maryland
Conditions: Huntington's Disease
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Intensive Education Versus Usual Education of Patients for Improving Guideline Directed Medical Therapy (GDMT) Prescription in Heart Failure With Reduced Ejection Fraction
NCT06273085
Recruiting
The goal of this randomized clinical trial is to test the effect of patient education on extent of use of guideline directed medical treatment (GDMT) of heart failure with reduced ejection fraction. The main question that our study aims to answer is if patient education can improve the adherence to GDMT in heart failure with reduced ejection fraction. Participants will receive educations about GDMT benefits in 1,3 and 5 months after discharge from hospital.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/22/2024
Locations: Medstar Union Memorial Hospital, Baltimore, Maryland
Conditions: Heart Failure, Patient Acceptance of Health Care
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Long-acting Naltrexone for Pre-release Prisoners
NCT02867124
Recruiting
This proposed five-year study will focus on whether the addition of providing XR-NTX treatment at a patients' place of residence will increase adherence and thus efficacy of the medication.Following initial screening, informed consent, and medical examination, pre-release prisoners at each facility will be block randomized (N=240) within gender to either: Condition 1. XR-NTX-OTx (n=120): One injection of XR-NTX in prison, followed by six monthly injections post-release in the community at an opi... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/22/2024
Locations: Maryland Department of Public Safety and Correctional Services, Towson, Maryland
Conditions: Opiate Addiction
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Virtual Reality as Distraction Analgesia and Anxiolysis for Pediatric Otolaryngology Procedures
NCT06245395
Recruiting
The primary aim of this randomized controlled trial is to determine the efficacy of Virtual Reality in pediatric otolaryngology clinics as distraction analgesia and anxiolysis for patients undergoing otologic procedures.
Gender:
ALL
Ages:
Between 7 years and 17 years
Trial Updated:
02/21/2024
Locations: Walter Reed National Military Medical Center, Bethesda, Maryland
Conditions: Virtual Reality, Otolaryngology
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The Effect of Teprotumumab on Thyroid Eye Disease and Thyroid Dysfunction
NCT06275373
Recruiting
This protocol studies the clinical outcome of patients with active thyroid disease with visually significant signs and symptoms of proptosis, pain, diplopiam lid/orbital edema, or lid/orbital erythema recommended for treatment with teprotumumab infusion (Tepezza®). Patients recommended for treatment will be evaluated by an oculoplastic surgeon (Dr. Eva Chou) and endocrinologist (Dr. Thanh Hoang).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/16/2024
Locations: Walter Reed National Military Medical Center, Bethesda, Maryland
Conditions: Thyroid Eye Disease, Graves Ophthalmopathy, Graves Disease
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