Maryland is currently home to 2692 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Baltimore, Bethesda, Rockville and Annapolis. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
The R-CITY Project: A Collaborative Intervention With Teachers and Youth
NCT05585918
Recruiting
"R-CITY" refers to the Collaborative Intervention with Teachers and Youth to practice and apply the 4 "Rs" of equity literacy skills in the classroom - Recognizing, Responding, Restoring Relationships, and Resilience. R-CITY is a collaborative teacher- and youth-focused prevention intervention that offers equity literacy lessons to accompany the Second Step social and emotional learning (SEL) curriculum. The lessons are designed to build teachers' and students' "equity stamina" and promote SEL s... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/14/2023
Locations: Shepard Pratt Health System, Towson, Maryland
Conditions: Violence
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Post-Concussion Musculoskeletal Injury Risks
NCT05122728
Recruiting
Musculoskeletal injuries (MSKI) and traumatic brain injury (TBI) are the signature injuries of the ongoing military conflicts. MSKI affect 800,000 Service Members annually and TBI have impacted more than 350,000 in the past 19 years and account for 22% of all combat casualties. Concussion, a mild form of TBI, increases MSKI risk in physically active individuals, including Service Members. The overall goal of the study is to identify the neuromuscular control mechanisms that increase MSKI risk f... Read More
Gender:
ALL
Ages:
Between 18 years and 40 years
Trial Updated:
12/11/2023
Locations: Walter Reed National Military Medical Center, Bethesda, Maryland
Conditions: Musculoskeletal Injury
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Cognitive and Vascular Functioning Following TBI
NCT06034509
Recruiting
This observational study will examine the association of chronic traumatic cerebrovascular injury and cardiovascular risk factors with TBI-related cognitive impairment and vascular dementia. Cerebrovascular, inflammatory, and neurodegenerative blood biomarkers as well as clinical and neuroimaging data
Gender:
ALL
Ages:
Between 18 years and 74 years
Trial Updated:
12/06/2023
Locations: Walter Reed National Military Medical Center, Bethesda, Maryland
Conditions: Traumatic Brain Injury, Cognitive Decline, Vascular Dementia
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Recovery and Outcomes From Stroke
NCT04007757
Recruiting
The investigators will perform follow-up on 500 cases of deep and lobar intracerebral hemorrhage to perform advanced neuroimaging before 45 days post stroke, and evaluations of motor and cognitive function at baseline, 3 months and 6 months to determine predictors of recovery, progressive cognitive or functional impairment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/06/2023
Locations: University of Maryland, Baltimore, Maryland
Conditions: Intracerebral Hemorrhage
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Neuroplasticity in Auditory Aging_Project 2 Aims 1 and 2
NCT03475043
Recruiting
Millions of elderly adults in the USA have age related hearing loss (ARHL), a malady that affects half of adults 60-69 years, and the majority of older adults. This hearing loss not only impacts communication and functional ability, but also is strongly associated with cognitive decline and decreased quality of life. This project aims to develop effective strategies to compensate and reverse this process through a deeper understanding of plasticity and adaptive auditory function, and how to enga... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
11/29/2023
Locations: University of Maryland, College Park, Maryland
Conditions: Auditory Perceptual Disorders, Aging Problems
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Ivabradine for Long-Term Effects of COVID-19 With POTS Cohort
NCT05481177
Recruiting
The purpose of the study is three-fold. The primary aim is to identify the proportion of Long-Haul COVID (LHC) and non-LHC volunteers with relevant symptoms actually have postural orthostatic tachycardia syndrome (POTS). The second is to determine benefit of ivabradine treatment. Ivabradine is a drug approved to treat tachycardia in persons with heart failure. The third is to characterize risk factors and outcomes among volunteers with and without LHC. This will include comparison with COVID-19-... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
11/27/2023
Locations: Uniformed Services University, Bethesda, Maryland
Conditions: Postural Orthostatic Tachycardia Syndrome, Long Haul COVID
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Study of HQP1351 in Subjects With Refractory CML and Ph+ ALL
NCT04260022
Recruiting
A multi-center, open-label, randomized, phase Ib study to evaluate the pharmacokinetics (PK) of HQP1351 and to determine the recommended phase 2 dose (RP2D) of HQP1351 in subjects with CML chronic phase (CP), accelerated phase (AP), or blast phase (BP) or with Ph+ ALL, who have experienced resistance or intolerance to at least two tyrosine kinase inhibitors (TKIs) or in subjects with Ph+ B-cell precursor (BCP) ALL or lymphoid blast phase CML (CML LBP), who have experienced resistance or intolera... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/27/2023
Locations: University of Maryland, Baltimore, Maryland
Conditions: Leukemia, Myeloid, Chronic, Myeloid Leukemia, Chronic Myeloid Leukemia, Philadelphia Positive Acute Lymphoblastic Leukemia, B Cell Precursor Type Acute Leukemia
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The Youth Opioid Recovery Support (YORS) Intervention
NCT04173416
Recruiting
Youth are disproportionately affected by the current opioid crisis with catastrophic consequences, and young adults with opioid use disorder (OUD) often struggle with adherence to relapse prevention medications. The Youth Opioid Recovery Support (YORS) model is a promising, innovative, wrap-around approach that addresses barriers to medication adherence and treatment engagement in an effort to improve public health outcomes in this vulnerable young adult population. This study seeks to refine th... Read More
Gender:
ALL
Ages:
Between 18 years and 28 years
Trial Updated:
11/20/2023
Locations: Mountain Manor Treatment Center, Baltimore, Maryland
Conditions: Opioid-use Disorder, Medication Adherence
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Prospective Database Registry Study of Scoliosis in Children With Cerebral Palsy
NCT00680264
Recruiting
The purpose of this study is to determine the radiographic and clinical outcomes of Scoliosis surgical and non-operative treatment in patients with Cerebral Palsy.
Gender:
ALL
Ages:
Between 8 years and 21 years
Trial Updated:
11/20/2023
Locations: Johns Hopkins Medical Institute, Baltimore, Maryland
Conditions: Cerebral Palsy, Scoliosis
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Evaluation of the SafeSpace App Intervention
NCT06043596
Recruiting
The goal of this study is to evaluate the impact of SafeSpace Sexual Health App, an innovative sexual health promotion program focused on reducing sexual risk factors and promoting sexual and reproductive health and wellbeing among young people assigned female or intersex at birth, particularly Black and/or Latine youth, LGBTQ+ youth, youth in states with high teen birth rates and youth who live in rural communities. This study utilizes a two-arm randomized control trial design to measure impact... Read More
Gender:
FEMALE
Ages:
Between 14 years and 18 years
Trial Updated:
11/17/2023
Locations: Child Trends, Bethesda, Maryland
Conditions: Health Behavior, Health Care Utilization, Unprotected Sex, Sexually Transmitted Infections
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Use of Virtual and Augmented Reality Devices in Vestibular Physical Therapy for mTBI
NCT05326100
Recruiting
Rapidly evolving virtual reality (VR) and augmented reality (AR) technologies are being incorporated by many large-scale industries, and the medical field is no exception. One area that has gained significant attention in recent years is virtual rehabilitation which allows physical therapists to leverage state-of-the-art immersive virtual environments to uniquely address functional deficits in patients who are unresponsive to conventional treatment techniques. Advanced VR and AR technologies are... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/17/2023
Locations: Walter Reed National Military Medical Center (WRNMMC), Bethesda, Maryland
Conditions: MTBI - Mild Traumatic Brain Injury, Dysfunction of Vestibular System
Register for Updates
An Evaluation of Repeated Oral Doses of JNJ-64281802 Against DENV-3 Challenge
NCT05048875
Recruiting
The investigational study drug, JNJ-64281802, is being developed for the prevention and treatment of dengue infection. This study is hypothesizing that the highest dose of the investigational study drug is superior to receiving a placebo with respect to its antiviral activity in healthy adult participants inoculated with Dengue Serotype 3.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
11/09/2023
Locations: Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland
Conditions: Dengue
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