Maryland is currently home to 2668 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Baltimore, Bethesda, Rockville and Annapolis. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
PCOS Indirect and Intangible Economic Burden
NCT05903404
Recruiting
The primary purpose of the PCOS Indirect and Intangible Economic Buren study is to estimate the economic costs of having PCOS in terms of quality of life and work productivity. The population will include individuals with a clinical diagnosis of PCOS, individuals self-diagnosed with PCOS, individuals with symptoms of PCOS (e.g., hirsutism, irregular menstrual cycles), and demographic-matched controls without PCOS. This study is a sub-study of The PCOS Challenge Study.
Gender:
FEMALE
Ages:
Between 18 years and 80 years
Trial Updated:
06/05/2023
Locations: PCOS Challenge: The National Polycystic Ovary Syndrome Association, Bethesda, Maryland
Conditions: Polycystic Ovary Syndrome
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Natural History Study of and Genetic Modifiers in Spinocerebellar Ataxias
NCT01060371
Recruiting
Spinocerebellar ataxias (SCA) are genetic neurological diseases that cause imbalance, poor coordination, and speech difficulties. There are different kinds of SCA and this study will focus on types 1, 2,3, and 6 (SCA 1, SCA 2, SCA 3 , also known as Machado-Joseph disease and SCA 6). The diseases are rare, slowly progressive, cause increasingly severe neurological difficulties and are variable across and within genotypes. The purpose of this research study is to bring together a group of experts... Read More
Gender:
ALL
Ages:
6 years and above
Trial Updated:
05/30/2023
Locations: John Hopkins University, Baltimore, Maryland
Conditions: Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia Type 2, Spinocerebellar Ataxia Type 3, Spinocerebellar Ataxia Type 6
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Single Ascending Dose Safety and Tolerability of NTS-104 Healthy Adults
NCT05547438
Recruiting
NTS-104 TRIS will be administered as a single intravenous dose to healthy subjects at doses of 0.8, 4, 8 and 16 mg/kg in 4 Cohorts. Each cohort of 8 subjects will begin with dosing 2 sentinel subjects with one being given the investigational product and one the placebo. If no safety issues arise, dosing the remaining subjects in the cohort will begin. A Safety Review Committee will review the safety and pharmacokinetic data before approving escalation to the next dose level.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
05/24/2023
Locations: Parexel International EPCU Baltimore 7th floor, Baltimore, Maryland
Conditions: Acute Ischemic Stroke
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The Effect of Donepezil on Wound Healing
NCT04505670
Recruiting
The purpose of the study is to test effectiveness of donepezil to improve wound healing in patients with diabetic wounds that have not healed with standard treatment.
Gender:
ALL
Ages:
20 years and above
Trial Updated:
05/19/2023
Locations: University of Maryland Shore Medical Center at Easton, Easton, Maryland
Conditions: Wound Heal
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Risk Indicators of Sarcoidosis Evolution-Unified Protocol
NCT05567133
Recruiting
The purpose of this study is to develop prediction models that can prognosticate patients with sarcoidosis using clinical data and blood markers that can be obtained during a clinic visit.
Gender:
ALL
Ages:
19 years and above
Trial Updated:
05/10/2023
Locations: University of Maryland, Baltimore, Maryland
Conditions: Sarcoidosis, Pulmonary
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Speech Perception and High Cognitive Demand
NCT04997577
Recruiting
With advancing age, adults experience increasing speech understanding difficulties in challenging situations. Currently, speech-in-noise difficulties are rehabilitated by providing hearing aids. For older normal-hearing adults, however, hearing devices do not provide much benefit since these adults do not have decreased hearing sensitivity. The goal of the "Speech Perception and High Cognitive Demand" project is to evaluate the benefit of a new auditory-cognitive training paradigm. In the presen... Read More
Gender:
ALL
Ages:
Between 65 years and 85 years
Trial Updated:
05/09/2023
Locations: Department of Hearing and Speech Sciences, College Park, Maryland
Conditions: Speech Intelligibility, Aging
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Project PEER: Understanding the Lung Cancer Patient ExperiEnce in the Real-World Setting
NCT05826756
Recruiting
LUNGevity Foundation, a non-profit lung cancer organization, wants to learn about living with lung cancer from the point of view of people with lung cancer and their family and friends who provide care. To do this, we have an online study designed to better understand how treatments people living with lung cancer receive impact their quality of life. Participants will complete surveys once a month for 12 months. What does participation involve? 1. Emailing the study team to learn more and get... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/26/2023
Locations: LUNGevity Foundation, Bethesda, Maryland
Conditions: Lung Cancer Patients, Caregivers
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The PCOS Challenge Study
NCT05797909
Recruiting
The primary purpose of The PCOS Challenge Study will be to conduct high-quality research where patients are included in the design, and answering the questions that patients identify as important to their lived experience with PCOS. In partnership with clinical investigators, patients will work on the development and management of data collection, the research agenda, and the sharing of research findings. The PCOSC Study will promote the advancement of research that provides reliable, useful, an... Read More
Gender:
FEMALE
Ages:
Between 12 years and 80 years
Trial Updated:
03/22/2023
Locations: PCOS Challenge: The National Polycystic Ovary Syndrome Association, Bethesda, Maryland
Conditions: Polycystic Ovary Syndrome
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Rett Syndrome Registry
NCT05432349
Recruiting
The Rett Syndrome Registry is a longitudinal observational study of individuals with MECP2 mutations and a diagnosis of Rett syndrome. Designed together with the IRSF Rett Syndrome Center of Excellence Network medical directors, this study collects data on the signs and symptoms of Rett syndrome as reported by the Rett syndrome experts and by the caregivers of individuals with Rett syndrome. This study will be used to develop consensus based guidelines for the care of your loved ones with Rett s... Read More
Gender:
ALL
Ages:
Between 0 years and 99 years
Trial Updated:
01/09/2023
Locations: Kennedy Krieger Institute, Baltimore, Maryland
Conditions: Rett Syndrome, Rett Syndrome, Atypical, Genetic Disease, Genetic Diseases, X-Linked, Intellectual Disability, Neurobehavioral Manifestations, Neurologic Manifestations, Neurologic Disorder, Neurodevelopmental Disorders, Nervous System Diseases
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Knee Related Subchondral Bone Lesions Treated With IOBP
NCT05314608
Recruiting
The study will be a prospective, multicenter clinical study evaluating clinical and patient reported outcome measures of subjects receiving IOBP® surgical technique using Angel cPRP and BMA processing system to treat subchondral bone pathology (SBP).
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
12/02/2022
Locations: TidalHealth Peninsula Regional, Inc., Salisbury, Maryland
Conditions: Subchondral Cyst
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First in Human Phase 1 Study of AG01 Anti-Progranulin/GP88 Antibody in Advanced Solid Tumor Malignancies
NCT05627960
Recruiting
This is a first in human phase 1 study of AG01 an anti-Progranulin/Glycoprotein88 (PGRN/GP88) antibody in patients with advanced solid tumors. AG01 is a recombinant monoclonal antibody expressed in a CHO production cell line. The antibody AG01 binds to human PGRN/GP88, expressed on cancer cells. This study will have a dose escalation portion (1A) to evaluate maximum tolerated dose (MTD) and/or maximum administered dose (MAD), the safety and tolerability of AG01treatment before the dose expansio... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/16/2022
Locations: University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, Maryland
Conditions: Triple Negative Breast Cancer, Hormone-Resistant Breast Cancer, Non Small Cell Lung Cancer, Mesothelioma
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Regional or Extend LymphAdenectomy During Resection of Intrahepatic Cholangiocarcinoma
NCT04078230
Recruiting
Intrahepatic cholangiocarcinoma (ICC) is one of the common malignant tumors. Lymph node metastasis is an important factor affecting the poor prognosis of intrahepatic cholangiocarcinoma. The eighth edition of the AJCC guidelines recommends at least 6 lymph nodes to be used for staging. The American Hepatobiliary and Pancreatic Association also recommends the removal of hilar lymph nodes as part of the radical surgery for intrahepatic cholangiocarcinoma. However, some scholars have found that pat... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
11/07/2022
Locations: The Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Intrahepatic Cholangiocarcinoma
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