Trial of Intravenous Fenretinide Emulsion for Patients With Relapsed/Refractory Peripheral T-cell Lymphomas
Recruiting
This study addresses the hypothesis that intermittent treatment with fenretinide intravenous emulsion will induce objective responses in patients with relapsed or refractory Peripheral T-cell Lymphoma (PTCL) who have failed at least one prior systemic therapy and will result in acceptable toxicities.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/22/2019
Locations: Hackensack University Medical Center, Hackensack, New Jersey
Conditions: Peripheral T-cell Lymphoma
Second-line Study of PEGPH20 and Pembro for HA High Metastatic PDAC
Recruiting
This study is the study of the combination of PEGPH20 and Pembrolizumab (MK-3475) for patients with previously treated Hyaluronan High (HA-high) metastatic pancreatic ductal adenocarcinoma. This study is an interventional, unblinded, open label study. Approximately 35 subjects will be enrolled. The trial will require approximately a total of 18 months, including 12 months for enrollment, with an additional 6 months for patient follow-up, data collection and study closure. Each subject will part... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/03/2019
Locations: Rutgers - Cancer Institute of New Jersey (CINJ), New Brunswick, New Jersey
Conditions: Pancreatic Ductal Adenocarcinoma, Pancreatic Cancer, Pancreatic Neoplasms
The Efficacy of Denosumab in Incomplete Patients Spinal Cord Injury
Recruiting
The purpose of this study is to determine the usefulness of a drug, denosumab, to prevent the loss of bone in participants legs due to SCI. This drug is FDA approved to treat osteoporosis in women after menopause who have an increased risk for fractures, to treat women receiving certain treatments for breast cancer who have an increased risk of fractures, and to treat bone loss in men receiving certain treatments for prostate cancer who have increased risk for fractures. This drug is considered... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/06/2019
Locations: Kessler Institute for Rehabilitation, West Orange, New Jersey
Conditions: Secondary Osteoporosis, Spinal Cord Injury
Nerve Stimulator for Patients With Upper Extremity Disease, Vascular or Orthopedic Surgery
Recruiting
To help determine if there is improved pain relief when a device that makes an arm muscle move (nerve stimulator) is used to place a needle in the area above the collarbone to prevent feeling of pain (anesthesia) of the upper arm.
Gender:
All
Ages:
Between 21 years and 89 years
Trial Updated:
09/04/2018
Locations: Robert Wood Johnson University Hospital, New Brunswick, New Jersey
Conditions: Other Biomechanical Lesions of Upper Extremity
Prospective Outcomes Study: Vectra® DA Guided Care Compared to Usual Care
Recruiting
In this 12-month multi-center prospective, site-randomized, two-arm trial, approximately 318 biologic-naïve subjects with RA who are candidates for treatment intensification due to inadequate response to MTX monotherapy will be enrolled at up to 60 study sites.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
07/27/2018
Locations: Summit Medical Group, Berkeley Heights, New Jersey
Conditions: Arthritis, Rheumatoid
TRT in Combination With Electrical Stimulation and Standing: Effect on Muscle and Bone in Spinal Cord Injured Males
Recruiting
The aim of this study is to understand what happens to muscle and bone in spinal cord injured males after four months of training using stand training, with body weight support (BWS), with testosterone replacement therapy (TRT), and electrical stimulation (ES). Specifically, researchers will investigate nerve, muscle, and bone changes in the lower limbs in response to stand training and ES when combined with TRT compared to i) standing alone with TRT; ii) stand training alone with placebo; iii)... Read More
Gender:
Male
Ages:
Between 18 years and 58 years
Trial Updated:
08/18/2017
Locations: Kessler Foundation, West Orange, New Jersey
Conditions: Spinal Cord Injury
Process and Outcomes in CBT for Anxious and Depressed Youth
Recruiting
The current study will evaluate the predictors, mediators, outcomes, and critical therapy processes associated with manual-based psychological therapies for 400 youth (ages 7-16 years) with anxiety and/or depression seeking services within a semi-natural clinic setting. Essentially, this study seeks to determine "what works" about psychological therapy for youth.
Gender:
All
Ages:
Between 7 years and 17 years
Trial Updated:
03/28/2017
Locations: Rutgers University (Youth Anxiety and Depression Clinic), Piscataway, New Jersey
Conditions: Anxiety Disorders, Depression
Efficacy of Implantable Defibrillator Therapy After a Myocardial Infarction
Recruiting
This study will assess whether an implantable defibrillator will increase the likelihood of survival in patients who have had a heart attack in the prior 5 years, have abnormal test results from a 24 hour heart monitor, and who have low normal heart function.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
07/07/2016
Locations: The Valley Hospital, Ridgewood, New Jersey
Conditions: Myocardial Infarction, Sudden Death