There are currently 125 active clinical trials seeking participants for Dementia research studies. The states with the highest number of trials for Dementia participants are Florida, California, New York and Maryland.
CONFIDENCE-AI Financial Education for Caregivers (CONFIDENCE-AI)
NCT06134180
Recruiting
The intervention being tested, CONFIDENCE-AI is a refined version of the original CONFIDENCE intervention made to reduce psychological financial strain and improve management of out-of-pocket care costs while increasing caregiver resourcefulness skills. Participants will be asked to participate in a 4-week intervention that includes participation in four, synchronous group-based Zoom sessions as well as between-session activities to apply learning. Participants will also receive tailored text me... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/23/2024
Locations: Case Western Reserve University, Cleveland, Ohio
Conditions: Alzheimer Disease, Dementia, Caregiver Burden, Financial Stress
Register for Updates
Learning Skills Together Family Caregiver Complex Intervention
NCT05846984
Recruiting
Learning Skills Together (LST) is a 6-week psychoeducational intervention focused on complex care (nursing) tasks completed by family caregivers to persons living with Alzheimer's Disease and related dementias. This study aims to test the efficacy of LST at reducing caregiver depression and negative appraisal of behavioral symptoms of dementia by building caregiver self-efficacy. To do this, eligible participants will be randomized into an intervention group (LST) or a control group condition fo... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/30/2024
Locations: Case Western Reserve University, Cleveland, Ohio
Conditions: Dementia, Alzheimer Disease, Caregiver Burden, Self Efficacy
Register for Updates
LifeBio Memory Digital Reminiscence Platform
NCT04769466
Recruiting
Non-pharmacological interventions and person-centered care strategies are important elements of care for people with Alzheimer's disease and related dementias. Life story work, which uses written and oral life histories to elicit conversation and memories, is an effective intervention for individuals with dementia; however, because of the time-consuming nature of generating useful life story materials, has not been widely implemented in nursing homes and other care environments. LifeBio Inc. wil... Read More
Gender:
All
Ages:
Between 18 years and 112 years
Trial Updated:
07/27/2023
Locations: Benjamin Rose Institute on Aging, Cleveland, Ohio
Conditions: Dementia, Cognitive Impairment
Register for Updates
New IDEAS: Imaging Dementia-Evidence for Amyloid Scanning Study
NCT04426539
Recruiting
New IDEAS is an observational, open-label, longitudinal cohort study designed to address the requirements of the CED provisions of the NCD on beta-amyloid PET. Building on the initial Imaging Dementia-Evidence for Amyloid Scanning (IDEAS) study, New IDEAS will evaluate the association between amyloid PET and patient-centered outcomes in an expanded and more ethnoracially and clinically diverse group of Medicare participants presenting with cognitive impairment.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/15/2024
Locations: Full list of Active Sites and Imaging Facilities, Philadelphia, Pennsylvania
Conditions: Alzheimer's Disease, Dementia, Mild Cognitive Impairment
Register for Updates
Alzheimer's Disease Neuroimaging Initiative 4
NCT05617014
Recruiting
Since its launch in 2004, the overarching aim of the Alzheimer's Disease Neuroimaging Initiative (ADNI) Study has been to validate biomarkers for Alzheimer's disease (AD) clinical trials. ADNI4 continues the previously funded ADNI1, ADNI-GO, ADNI2, and ADNI3 studies that have combined public/private collaborations between academia and industry to determine the relationships between the clinical, cognitive, imaging, genetic and biochemical biomarker characteristics of the entire spectrum of AD.
Gender:
All
Ages:
Between 55 years and 90 years
Trial Updated:
05/14/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama +40 locations
Conditions: Mild Cognitive Impairment, Alzheimer Disease, Dementia
Register for Updates
5-Cog 2.0: A Pragmatic Clinical Trial
NCT05515224
Recruiting
Cognitive impairment related to dementia is frequently under-diagnosed in primary care settings. This problem is more prevalent in health disparities populations. The investigators developed the 5-Cog brief cognitive assessment that is simple to use, standardized, takes <5 minutes, does not require informants, and accounts for major technical, cultural, and logistical barriers of current assessments. The investigators propose a hybrid Type 1 effectiveness-implementation design in real-world sett... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
05/13/2024
Locations: Indiana University, Bloomington, Indiana +1 locations
Conditions: Dementia, Cognitive Impairment
Register for Updates
Promoting Goals-of-Care Discussions for Patients With Memory Problems and Their Caregivers
NCT05596760
Recruiting
The goal of this clinical trial is to improve communication among clinicians, patients with memory problems, and their family members. We are testing a way to help clinicians have better conversations to address patients' goals for their healthcare. To do this, we created a simple, short guide called the "Jumpstart Guide." The goal of this research study is to show that using this kind of guide is possible and can be helpful for patients and their families. Patients' clinicians may receive a Jum... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/10/2024
Locations: Harborview Medical Center, Seattle, Washington +2 locations
Conditions: Dementia, Chronic Disease, Neoplasm Metastasis, Lung Neoplasm, Pulmonary Disease, Chronic Obstructive, Heart Failure，Congestive, Liver Cirrhosis, Kidney Failure, Chronic, Lung Diseases, Interstitial, Peripheral Vascular Diseases, Diabetes With End Organ Damage, Palliative Care, Patient Care, Health Care Quality, Access, and Evaluation, Patient Care, Health Communication, Patient Care Planning, Quality of Life
Register for Updates
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001
NCT01760005
Recruiting
The purpose of this study is to assess the safety, tolerability, biomarker, cognitive and clinical efficacy of investigational products in participants with an Alzheimer's disease-causing mutation by determining if treatment with the study drug slows the rate of progression of cognitive/clinical impairment or improves disease-related biomarkers.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
05/10/2024
Locations: University of Alabama in Birmingham, Birmingham, Alabama +38 locations
Conditions: Alzheimers Disease, Dementia, Alzheimers Disease, Familial
Register for Updates
The Active Mind Trial: An Adaptive Randomized Trial to Improve Function and Delay Dementia
NCT04171323
Recruiting
Older adults at risk for dementia show a variety of cognitive deficits, which can be ameliorated by different cognitive training (CT) exercises. The best combination of CT exercises is unknown. The aim is to discover the most efficacious combination of CT exercises as compared to cognitive stimulation (which will serve as a stringent, active control) to modify the functional trajectories of older adults' with MCI, who are at high risk for dementia. The primary objective of the U01 phase was to d... Read More
Gender:
All
Ages:
Between 55 years and 89 years
Trial Updated:
05/09/2024
Locations: University of California San Francisco, San Francisco, California +4 locations
Conditions: Age-related Cognitive Decline, Mild Cognitive Impairment, Dementia
Register for Updates
Self-Care for Dementia Caregivers
NCT05309577
Recruiting
The Self-care for Dementia Caregivers Study is a behavioral health intervention that uses digital monitoring tools and motivational health coaching to help caregivers of persons with dementia engage in a regular routine of self-care. Participants wear an apple watch for the objective collection of sleep-wake rhythms. They receive personalized feedback on their sleep-wake rhythms via a new app. Health coaches call participants weekly, for 6 weeks to help participants meet their health/sleep goals... Read More
Gender:
All
Ages:
Between 50 years and 99 years
Trial Updated:
05/09/2024
Locations: University of Pittsburgh, Pittsburgh, Pennsylvania
Conditions: Aging, Mental Disorder, Eating, Healthy, Physical Inactivity, Prodromal Symptoms, Sleep, Alzheimer Disease, Dementia, Circadian Rhythm Disorders
Register for Updates
HEARS-SLP: Providing SLP-Delivered Hearing Health Care to Individuals With Cognitive Impairment
NCT06008782
Recruiting
Building upon the HEARS audiologist-community health worker (CHW) model, this study intervention will be delivered by a speech-language pathologist (SLP). The primary objective of the study is to develop and test an affordable and accessible hearing rehabilitative intervention that will be delivered by a SLP to individuals with cognitive impairment.
Gender:
All
Ages:
Between 60 years and 100 years
Trial Updated:
05/08/2024
Locations: Johns Hopkins Medicine, Baltimore, Maryland
Conditions: Hearing Loss, Dementia, Cognitive Impairment
Register for Updates
Palliative Care for Patients With Dementia
NCT05749146
Recruiting
A multi-site, single-blinded, parallel, randomized-controlled trial to evaluate the effectiveness of a novel model of in-home palliative care for dementia patients and their family caregivers. From inpatient and outpatient settings associated with four hospitals across New York City, patients with advanced dementia and their family caregivers will be randomized to intervention or augmented control.
Gender:
All
Ages:
65 years and above
Trial Updated:
05/08/2024
Locations: Ichan School of Medicine at Mount Sinai, New York, New York
Conditions: Dementia
Register for Updates