New York is currently home to 4503 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Persona MC vs PS RCT With ROSA
Recruiting
A randomized, controlled study comparing two total knee implant devices, Persona medial congruent (MC) vs posterior stabilized (PS). These surgeries will be performed using the ROSA robotic system. Patients will be followed up to 5 years.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/28/2025
Locations: NYU Langone Health, New York, New York
Conditions: Total Knee Arthroplasty
NIH RECOVER Tissue Pathology: Understanding the Long-Term Impact of COVID-19
Recruiting
The Post-Acute Sequelae of SARS-CoV-2 (PASC) Autopsy Study is a cross-sectional study designed to define and characterize the epidemiology, natural history, clinical spectrum, and underlying mechanisms of post-acute effects of SARS-CoV-2 infection in a diverse population representative of the general COVID-19 population in the US. The autopsy study will characterize the pathology of PASC in (i) non-hospitalized patients who die 30 days or later from symptom onset of COVID-19, and (ii) hospitaliz... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/28/2025
Locations: NYU Langone Health, New York, New York
Conditions: COVID-19, SARS CoV 2 Infection
Endoscopic Evidence of Maintenance of Healing With Oral NEXIUM in Patients 1 to 11 Years Old With Erosive Esophagitis.
Recruiting
The aim of the study is to compare the safety and efficacy of two doses of Nexium in maintaining healing of erosive esophagitis in patients 1 to 11 years of age.
Gender:
ALL
Ages:
Between 1 year and 11 years
Trial Updated:
07/28/2025
Locations: Research Site, Bronx, New York
Conditions: Erosive Esophagitis
GEMINI-NSCLC: NSCLC Biomarker Study
Recruiting
GEMINI NSCLC Study is a non-interventional study that will be collecting clinical and molecular health information from patients with NSCLC who will receive longitudinal blood collection in addition to their standard of care therapy and disease surveillance with the goals of identifying the molecular evolution of lung cancer with standard of care therapy, and determining the utility of ctDNA dynamics to predict risk of recurrence and therapeutic outcomes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/28/2025
Locations: New York Oncology Hematology, Albany, New York
Conditions: Non-Small Cell Lung Cancer
Pembrolizumab, Olaparib, and Temozolomide for People With Glioma
Recruiting
This study will test the safety and effectiveness of a combination of pembrolizumab, olaparib, and temozolomide to see how well these drugs work when given together in people with a glioma that either did not respond to previous treatment or came back after treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/28/2025
Locations: Memorial Sloan Kettering Suffolk -Commack (Limited Protocol Activities), Commack, New York
Conditions: Glioma
A Study to Examine the Effects of Novel Therapy Linvoseltamab in Combination With Other Cancer Treatments for Adult Patients With Multiple Myeloma That is Resistant to Current Standard of Care Treatments
Recruiting
This study is researching an experimental drug called linvoseltamab in combination with other drugs for the treatment of a blood cancer called multiple myeloma. Linvoseltamab has previously been studied as a single agent (without other cancer treatments) in participants with multiple myeloma that returned after prior therapies and needed to be treated again. In the initial study, some participants treated with linvoseltamab had improvement of their myeloma, including complete responses (no evid... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/28/2025
Locations: Weill Cornell Medicine/New York Presbyterian Hospital, New York, New York
Conditions: Multiple Myeloma
Safety, Efficacy and Tolerability of Ianalumab Versus Placebo, Combination With SoC Therapy, in Participants With Active Lupus Nephritis
Recruiting
This trial will evaluate efficacy, safety, and tolerability of subcutaneous (s.c.) ianalumab given every 4 weeks (q4w) or every 12 weeks (q12w) compared to placebo, in combination with SoC, in adult participants with active LN
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
07/28/2025
Locations: James J Peters VA Medical Center, Bronx, New York
Conditions: Lupus Nephritis
Trifecta-Heart cfDNA-MMDx Study
Recruiting
Demonstrate the relationship between DD-cfDNA levels and HLA antibodies in blood transplant recipient and the Molecular Microscope® (MMDx) Diagnostic System results in indication and protocol biopsies from heart transplants.
Gender:
ALL
Ages:
All
Trial Updated:
07/28/2025
Locations: Montefiore Medical Center, 3319 Rochambeau Avenue, 2nd FL, Bronx, New York
Conditions: Heart Transplant Rejection
Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders
Recruiting
This is a single-arm study to investigate 1-year treatment related mortality (TRM) in patients with life threatening non-malignant and malignant hematologic disorders who do not have a matched related donor for allogeneic transplantation.
Gender:
ALL
Ages:
21 years and below
Trial Updated:
07/28/2025
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: MDS, AML, ALL, MPD Withou Myelofibrosis, NHL or HL, Inherited Metabolic Disorders, Hemoglobinopathies, Bone Marrow Failure, HLH
Secukinumab Open Label Roll-over Extension Protocol
Recruiting
The purpose of this study is to assess long term safety in participants who have completed a Novartis trial with secukinumab, have been judged by the investigator to benefit from continued treatment with secukinumab, and are unable to obtain the marketed secukinumab formulation.
Gender:
ALL
Ages:
Between 6 years and 100 years
Trial Updated:
07/28/2025
Locations: St Lawrence Health System, Potsdam, New York
Conditions: Autoimmunity, Inflammation
Exercise Therapy to Improve Cardiovascular Health in Post-Menopausal Women After Treatment for Early Stage Breast Cancer
Recruiting
This study will compare the effects on cardiorespiratory fitness (CRF) of aerobic exercise in different amounts (number of minutes/session) over different periods of time (number of weeks). Aerobic exercise is physical activity of light-to-moderate intensity that uses the large muscle groups (muscles in your legs, buttocks, back, and chest) and can be performed for at least 10 minutes. The researchers will study the effects of different exercise programs on how well the study participants' bodi... Read More
Gender:
FEMALE
Ages:
Between 21 years and 80 years
Trial Updated:
07/28/2025
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Early Stage Breast Cancer
Cerebrospinal Fluid Biomarkers in Bariatric Surgery
Recruiting
The goal of this project is to understand why bariatric surgery is such an effective treatment for obesity with a focus on brain mechanisms. Cerebrospinal fluid (CSF) neuropeptide, hormone and protein levels will be measured as a surrogate for changes in brain activity in participants before and after bariatric surgery as compared with participants before and after diet-induced weight loss. The investigators are studying neuropeptides and hormones that are know to be involved with the regulation... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
07/28/2025
Locations: Columbia University Medical Center, New York, New York
Conditions: Obesity