New York is currently home to 4599 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Dissecting the Heterogeneity of Oral Cancer Pain
Recruiting
Oral squamous cell carcinoma (SCC) produces a higher prevalence and more severe pain than all other cancers. Orofacial pain is one of the most common initial symptoms of oral cancer and often leads to the diagnosis of oral cancer. However, the character, severity, and unique features of oral cancer widely differ between patients. There is currently no effective and lasting treatment available to alleviate suffering from oral cancer pain. A significant obstacle to effectively treating cancer pai... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/26/2022
Locations: New York University College of Dentistry, New York, New York
Conditions: Oral Squamous Cell Carcinoma
Home With TablO outcoMEs (HOME) Registry
Recruiting
Prospective, multicenter, single arm, post-market study to evaluate real world clinical outcomes in ESRD patients receiving in-home dialysis on the Tablo Hemodialysis System.
Gender:
All
Ages:
15 years and above
Trial Updated:
09/22/2022
Locations: Parker Jewish Institute, New Hyde Park, New York
Conditions: End Stage Renal Disease
Genes and Environment in Multiple Sclerosis
Recruiting
The purpose of the research study is to identify the genetic, environmental and immune profiles that may increase a person's risk of developing multiple sclerosis (MS). While MS is not a disease caused by a single variation in genetic material (DNA), a single environmental factor, or a single malfunction in immune cells, there are genetic alterations, environmental exposures and immunologic factors that make the development of MS more likely. Obtaining information about who is at risk for MS wil... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/16/2022
Locations: Columbia University Irving Center, New York, New York
Conditions: Multiple Sclerosis
Envi™-SR Randomized Controlled Trial for Endovascular Treatment of Ischemic Stroke
Recruiting
The study objective is to examine and compare clinical outcomes, as measured by Modified Rankin Scale (mRS) at 90 days (± 15 days) post treatment, and related performance characteristics of the Envi™-SR and concurrent parallel Control Devices currently cleared by the U.S. FDA for treatment of stroke.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/15/2022
Locations: North Shore University Hospital, Manhasset, New York
Conditions: Acute Ischemic Stroke
Rare and Atypical Diabetes Network
Recruiting
RADIANT is a network of 14 clinical sites and several laboratories dedicated to the study of atypical diabetes. The objective of this study is to define new forms of diabetes and the unique mechanisms underlying these forms of atypical diabetes. The specific aims are to: Identify and enroll individuals and families with undiagnosed rare and atypical forms of diabetes. Determine the etiologic basis of the metabolic disorder among individuals and families with novel forms of rare and atypical di... Read More
Gender:
All
Ages:
All
Trial Updated:
09/14/2022
Locations: SUNY Downstate Health Sciences University, Brooklyn, New York
Conditions: Diabetes Mellitus, Diabetes Mellitus Progression, Glucose Intolerance, Glucose Metabolism Disorders, Metabolic Disease, Endocrine; Complications, Endocrine System Diseases
Safety, Tolerability, and Efficacy of AXA1125 in NASH With Fibrosis
Recruiting
This study will compare the effects of AXA1125, an orally active mixture of amino acids, compared to placebo, on improving fat and inflammation (steatohepatitis) as well as fibrosis in subjects with non alcoholic steatohepatitis (NASH). as well as the safety and tolerability of AXA1125. Subjects will take one of two different doses of AXA1125 or a placebo twice daily, and a liver biopsy will be done at the beginning and end of the 48-week study.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/07/2022
Locations: Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: Non Alcoholic Steatohepatitis (NASH)
A Study of MRG004A in Patients With Tissue Factor Positive Advanced or Metastatic Solid Tumors
Recruiting
The objective of this study is to evaluate the safety, efficacy, pharmacokinetics, and immunogenicity of MRG004A in patients with Tissue Factor positive advanced or metastatic solid tumors.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/06/2022
Locations: Memorial Sloan Kettering 60th Street Outpatient Center, New York, New York
Conditions: Advanced or Metastatic Solid Tumors
An Exploratory, Open-Label, Oligo-Center Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Intravenous DNV3837 in Subjects With Clostridium Difficile Infection
Recruiting
This is an open-label study to evaluate the safety, efficacy, and PK of DNV3837 at a dose of 1.5 mg/kg actual body weight(BW)/day administered via IV infusion in subjects with CDI. The study will be conducted in 2 subsequent parts. In Part 1 of the study, 10 subjects of either sex with severe or non-severe CDI will be enrolled to receive DNV3837. In Part 2 of the study, up to 30 subjects with severe or non-severe CDI will be enrolled to receive DNV3837. In both parts of the study, treatment i... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/06/2022
Locations: DiGiovanna Institute for Medical Education and Research, North Massapequa, New York
Conditions: Clostridium Difficile (C. Difficile)
High Intensity Interval Gait Training in Multiple Sclerosis
Recruiting
Over 90% of persons with MS (pwMS) complain of difficulty with walking. High intensity interval gait training (HIIGT), where persons alternate brief periods of walking at high speeds with periods of rest has been found to improve walking in other neurologic diagnoses. However its impact on pwMS is not known. Most gait training in MS is done continuously at a slower pace. The purpose of this study is to compare the effects of HIIGT to traditional Moderate Intensity Continuous Gait Training (MICGT... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
09/02/2022
Locations: Hunter College, New York, New York
Conditions: Multiple Sclerosis,Gait, Exercise
Beyond Listening: A Music-based Intervention
Recruiting
Study will be conducted to determine if caregivers who use music at home will feel less burden and whether the person they are caring for will demonstrate decreased symptoms of dementia. Caregivers will participate in a series of psycho-educational trainings for six weeks. During this time, caregivers will learn how to use singing, music listening and music with movement with their family member. Caregivers should feel less stressed and a decreased sense of burden. The care recipient should appe... Read More
Gender:
Female
Ages:
All
Trial Updated:
08/23/2022
Locations: Menorah Center for Nursing and Rehabilitation, Brooklyn, New York
Conditions: Alzheimer's Disease (Incl Subtypes), Depressive Symptoms
Intranasal Oxytocin vs. Placebo for the Treatment of Hyperphagia in Prader-Willi Syndrome
Recruiting
This study is a phase 2 randomized double blind 8-week treatment trial of intranasal OXT vs. placebo in 50 subjects aged 5 to 17 years with PWS in order to assess IN-OXT's affect on measurements of (1) eating behaviors (2) repetitive behaviors (3) weight and body composition (4) quality of life (5) salivary OXT and hormone levels (including ghrelin, pancreatic polypeptide, peptide YY, GLP-1, insulin, glucagon, testosterone, and estrogen). If superior to placebo, this data will add to the current... Read More
Gender:
All
Ages:
Between 5 years and 17 years
Trial Updated:
08/19/2022
Locations: Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York
Conditions: Prader-Willi Syndrome, Hyperphagia
Shafer Width and Girth: The Use of Injectable Fillers for Penile Enhancement
Recruiting
Injectable filler will be performed by Principal Investigator under sterile conditions for the enhancement of girth and surface area of the penis.
Gender:
Male
Ages:
Between 21 years and 65 years
Trial Updated:
08/18/2022
Locations: Shafer Clinic Fifth Avenue, New York, New York
Conditions: Micropenis