New York is currently home to 4476 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Efficacy and Safety of Topical Clascoterone (WINLEVI) Cream 1% in Patients With Facial Acneiform Rosacea: A Phase 2 Clinical Trial
Recruiting
To demonstrate the efficacy of Clascoterone cream 1% in reducing the size of sebaceous glands in study participants with acneiform rosacea.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: New York Harbor VA Brooklyn Campus, Brooklyn, New York
Conditions: Papular-pustular Rosacea, Papulopustular Rosacea (PPR), Papulopustular Rosacea
Long-term Safety of Nipple Sparing Mastectomy in Women With GPV in Breast Cancer
Recruiting
Patients with a germline pathogenic variant (GPV) in high-penetrance breast cancer susceptibility genes who are considering risk reducing mastectomy (RRM) often strongly desire to keep their nipple areola complex but inquire as to whether it is safe to do so. Relative to traditional or skin sparing mastectomy (SSM) techniques, nipple sparing mastectomy (NSM) is associated with improved psychosocial and sexual well-being and is significantly better for body image and reducing feelings of disfigur... Read More
Gender:
FEMALE
Ages:
Between 18 years and 90 years
Trial Updated:
04/23/2025
Locations: Memorial Sloan Kettering Cancer Center (MSKCC), New York City, New York
Conditions: Breast Cancer Surgery
A Clinical Study to Evaluate the Safety and Efficacy of the FloStent in Men With Benign Prostatic Hyperplasia Symptoms
Recruiting
The goal of this study is to determine the safety and effectiveness of the FloStent, a medical device used to treat men with symptoms of Benign Prostatic Hyperplasia, compared to sham (procedure without deployment of the FloStent). All participants will undergo a flexible cystoscopy and those randomized to the treatment arm will receive the FloStent, while those randomized to the sham arm will not receive the FloStent.
Gender:
MALE
Ages:
45 years and above
Trial Updated:
04/23/2025
Locations: Manhattan Medical Research NYU Langone, New York City, New York
Conditions: Benign Prostatic Hyperplasia
Pilot Trial of Spiritual Care Interventions for Patients With Cancer
Recruiting
This is a pilot trial of the effects of spiritual care interventions on spiritual well-being and readiness to engage in advance care planning (ACP) among black patients with advanced cancer recruited from outpatient settings to determine the feasibility of conducting a larger trial of effects of early integration of spiritual care into outpatient oncology care on patient outcomes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, New York
Conditions: Advanced Cancer
A Study in Patients With Moderate to Severe Plaque Psoriasis to Evaluate the Efficacy and Safety of ESK-001
Recruiting
The goal of this clinical trial is to learn if ESK-001 works to treat moderate to severe plaque psoriasis. The main questions it aims to answer are: * Does ESK-001 reduce the severity of people's psoriasis? * How safe is ESK-001 in people with moderate to severe plaque psoriasis? The study includes 2 comparators: a placebo control (a 'dummy' tablet that does not contain the medicine ESK-001 but looks just like it) and an active control (apremilast, which is a medicine approved to treat psorias... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: NYC Health and Hospitals Elmhurst, Elmhurst, New York
Conditions: Plaque Psoriasis
Study of ALTO-101 in Patients With Schizophrenia
Recruiting
This is a Phase 2, double-blind, placebo-controlled, two-way crossover study to compare the efficacy of ALTO-101T versus placebo in change in electroencephalogram (EEG) cognitive processing markers and measures of cognition. Additional goals are to assess pharmacokinetic (PK), safety, and tolerability of the recently developed ALTO-101T transdermal delivery system (TDS) formulation in a patient population.
Gender:
ALL
Ages:
Between 21 years and 55 years
Trial Updated:
04/23/2025
Locations: Site 5077, New York, New York
Conditions: Schizophrenia, Cognitive Impairment
A Study Evaluating AMG 193 in Combination With Other Therapies in Participants With Advanced Gastrointestinal, Biliary Tract, or Pancreatic Cancers With Homozygous Methylthioadenosine Phosphorylase (MTAP)-Deletion
Recruiting
The study aims to determine maximum tolerated dose (MTD) or recommended combination dose of the MTA-cooperative PRMT5 inhibitor AMG 193 administered in combination with other therapies in adult participants with metastatic or locally advanced methylthioadenosine phosphorylase (MTAP)-deleted gastrointestinal, biliary tract, or pancreatic cancers. The study also aims to determine the safety profile of AMG 193 administered in combination with other therapies in adult participants with metastatic or... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
04/23/2025
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Advanced Gastrointestinal, Biliary Tract, and Pancreatic Cancers
A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis
Recruiting
A randomized, double-blind, placebo-controlled clinical study to evaluate the safety and efficacy of 2 doses of inhaled pirfenidone (AP01) versus placebo on top of standard of care in participants with PPF over 52 weeks.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: Montefiore Medical Center, Bronx, New York
Conditions: Progressive Pulmonary Fibrosis
Long-Term Follow-Up Study of Unilateral Microtia Patients Implanted With AUR-201
Recruiting
Long-term follow-up of unilateral microtia patients implanted with AUR-201.
Gender:
ALL
Ages:
Between 8 years and 29 years
Trial Updated:
04/23/2025
Locations: Romo Plastic Surgery, New York, New York
Conditions: Microtia
Subcutaneous Implant Combination Product (AUR-201) in Patients With Unilateral Microtia
Recruiting
AUR-201 is indicated for the treatment of Grade II, III, or IV unilateral microtia in patients 8 to 29 years of age.
Gender:
ALL
Ages:
Between 8 years and 29 years
Trial Updated:
04/23/2025
Locations: Romo Plastic Surgery, New York, New York
Conditions: Microtia
Safety and Efficacy of OBX-115 in Advanced Solid Tumors
Recruiting
This is a study to investigate the safety and efficacy of an investigational OBX-115 regimen in adult participants with advanced solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: Memorial Sloan Kettering (Melanoma/NSCLC), New York, New York
Conditions: Tumor Skin, Metastatic Melanoma, Melanoma, Lung Cancer, Metastatic Lung Cancer, Non Small Cell Lung Cancer, Metastatic Non Small Cell Lung Cancer
LS301-IT in Partial Mastectomy and Sentinel Lymph Node Biopsy (SLNB) for DCIS or Stage I-II Primary Invasive Breast Cancer
Recruiting
The aim of this Phase 1b/2 study is to investigate the safety, efficacy, and pharmacokinetics (PK) of a single dose of LS301-IT, a novel fluorescence imaging agent developed by Integro Theranostics (IT), administered by intravenous (IV) injection in female patients undergoing partial mastectomy for DCIS (whether or not undergoing planned SLNB) or Stage I-II primary invasive breast cancer undergoing SLNB. Safety is the primary objective of this study, followed by efficacy that will be assessed fr... Read More
Gender:
FEMALE
Ages:
Between 18 years and 80 years
Trial Updated:
04/23/2025
Locations: Integro Theranostics Research Site #6, Bronx, New York
Conditions: Breast Cancer, DCIS, Invasive Duct Carcinoma of Breast