New York is currently home to 4507 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Study of Radiation Therapy After Surgery in People With Oral Tongue Squamous Cell Carcinoma
Recruiting
This study will test whether limiting standard photon intensity modulated radiation therapy (IMRT) to exclude the oral tongue surgical site can decrease the risk of side effects caused by oral radiation. The researchers will also find out if this approach affects the rate of disease coming back after treatment (recurrence), and will measure participants' quality of life by having them complete questionnaires.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/23/2025
Locations: Memorial Sloan Kettering Suffolk - Commack, Commack, New York
Conditions: Oral Tongue Squamous Cell Carcinoma
Dose Optimization of MDMA-Assisted Therapy for PTSD
Recruiting
This open label, within-subjects dose optimization trial will investigate the optimal number of MDMA-Assisted Therapy treatment cycles (i.e., one MDMA session and three integration sessions) in a sample of U.S. veterans with PTSD. Participants will complete from one to five cycles of MDMA-AT.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/23/2025
Locations: James J. Peters VA Medical Center, Bronx, New York
Conditions: Posttraumatic Stress Disorder
A Study of EDG-7500 in Adults With Hypertrophic Cardiomyopathy (CIRRUS-HCM)
Recruiting
This study is being conducted in order to understand the safety and effects of different doses of EDG-7500 as a single dose in adults with obstructive hypertrophic cardiomyopathy (oHCM) and as multiple doses in adults with obstructive or nonobstructive hypertrophic cardiomyopathy (nHCM).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/23/2025
Locations: North Shore University Hospital, Manhasset, New York
Conditions: Hypertrophic Cardiomyopathy
miroliverELAP® for the Treatment of Acute Liver Failure: A Phase 1 Trial
Recruiting
The clinical trial will assess the safety of miroliverELAP for the treatment of acute liver failure without underlying chronic liver disease. miroliverELAP is an external liver assist combination product consisting of a single-use MIRO-001 bioengineered liver graft and an extracorporeal blood circuit. miroliverELAP Is intended to support the native (failed) liver for up to 48-hours of continuous treatment to allow time for liver recovery or to identify a transplantable liver.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
06/23/2025
Locations: Mount Sinai Recanati/Miller Transplantation Institute, New York, New York
Conditions: Acute Liver Failure, Acute Liver Injury, Drug Induced
The CardioClip Study
Recruiting
The CardioClip study is exploring the use of a wireless sensor to monitor pressure in the pulmonary artery. This sensor is inserted much like the mTEER procedure, a non-surgical method through a vein in the groin. The investigators want to find out if the sensor, by constantly sending information about heart function, can help improve patient outcomes. This means doctors could adjust medications based on real-time pressure changes detected by the sensor. The results from this study will help pav... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
06/23/2025
Locations: Columbia University Irving Medical Center / NewYork-Presbyterian Hospital, New York, New York
Conditions: Heart Failure With Reduced Ejection Fraction, Mitral Regurgitation
Advanced Diffusion Imaging in Renal Cancer Patients
Recruiting
The objective of this study is to apply advanced diffusion imaging in a two-pronged assessment of renal mass patients: (1) characterization of lesion malignancy and subtype, and (2) prediction of renal function stability or decline following partial nephrectomy.
Gender:
ALL
Ages:
Between 21 years and 85 years
Trial Updated:
06/23/2025
Locations: NYU Langone Health, New York, New York
Conditions: Renal Cancer
A Study To Learn About Two Study Medicines (PF-07275315 And PF-07264660) In People Who Have Moderate To Severe Atopic Dermatitis
Recruiting
The purpose of this study is to learn about the safety and effects of 2 study medicines (PF-07275315 and PF-07264660) for the treatment of atopic dermatitis (AD). AD is a long- lasting itchy red rash, caused by a skin reaction. This study is seeking participants who: * are 18 years of age or more. * Were confirmed to have AD at least 6 months ago. * Are not having an effective treatment result from medicines that are applied on skin for AD. * Are considered by their doctors to have moderate to... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/23/2025
Locations: Empire Dermatology, East Syracuse, New York
Conditions: Atopic Dermatitis
Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial
Recruiting
Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial (DECLARE) is a multi-center, outcome-masked, randomized clinical trial. The purpose of this study is to compare glaucoma drainage device implantation in the anterior chamber (front part of the eye) and sulcus (small space between iris and front chamber of the eye) in efforts to minimize cell loss in the eye.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/23/2025
Locations: University of Buffalo/State University of New York, Buffalo, New York
Conditions: Glaucoma
The Role of Mechanical Diagnosis and Therapy in the Management of Concussion
Recruiting
The purpose of this study is to examine the role of a Mechanical Diagnosis and Therapy (MDT) examination in identifying participants diagnosed with concussion who display a directional preference compared to who don't display a directional preference.
Gender:
ALL
Ages:
Between 13 years and 65 years
Trial Updated:
06/23/2025
Locations: Summit Healthplex Physcial Therapy/Niagara Falls Memorial Medical Center, Niagara Falls, New York
Conditions: Brain Concussion, Mild Traumatic Brain Injury
DCSZ11 as a Monotherapy and in Combination in Patients With Advanced or Metastatic Solid Tumors
Recruiting
This is a multicenter, open-label, Phase 1 study to assess the effects of DCSZ11 as a monotherapy and in combination in patients with advanced or metastatic solid tumors. The study consists of an Escalation Phase (Phase 1a) and a Dose Expansion/Optimization Phase (Phase 1b).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/23/2025
Locations: MonteFiore, Bronx, New York
Conditions: Advanced or Metastatic Solid Tumors
A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies
Recruiting
The goal of this clinical trial is to determine the safety and feasibility of allogeneic transplantation with bone marrow from a deceased donor in patients with acute and chronic leukemias, myelodysplastic syndrome, and certain lymphomas. Patients will either receive myeloablative conditioning or reduced intensity conditioning regimen prior to the transplant. Patients will be followed for 56 days for safety endpoints and remain in follow-up for one year.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
06/23/2025
Locations: Columbia University - Herbert Irving Comprehensive Cancer Center, New York, New York
Conditions: Acute Leukemia, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Acute Biphenotypic Leukemia, Acute Undifferentiated Leukemia, CLL (Chronic Lymphocytic Leukemia), Chronic Myeloid Leukemia (CML), MDS (Myelodysplastic Syndrome), Non-Hodgkin Lymphomas, Hodgkins Lymphoma, Cutaneous T Cell Lymphomas (CTCL)
Gedatolisib Plus Fulvestrant With or Without Palbociclib vs Standard-of-Care for the Treatment of Patients With Advanced or Metastatic HR+/HER2- Breast Cancer (VIKTORIA-1)
Recruiting
This is a Phase 3, open-label, randomized, clinical trial evaluating the efficacy and safety of gedatolisib plus fulvestrant with or without palbociclib for the treatment of patients with locally advanced or metastatic HR+/HER2- breast cancer following progression on or after CDK4/6 and aromatase inhibitor therapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/23/2025
Locations: New York Oncology Hematology, P.C. - Albany, Albany, New York
Conditions: Breast Cancer