New York is currently home to 4476 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Randomized Blinded Evaluation of the Effects of TENS and IFC Compared to a Sham Device and SOC in Patients With Non-Specific CLBP
Recruiting
This is a prospective, sham-controlled, randomized, single-blinded, multi-center study comparing two different modes of the NexWave device, transcutaneous electrical nerve stimulation (TENS) and interferential current (IFC), with an identical non-functioning NexWave sham device or self-defined standard of care for improvement of pain intensity of non-specific CLBP.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
04/16/2025
Locations: One Oak Medical, Congers, New York
Conditions: Non-Specific Chronic Lower Back Pain
Telehealth-Enhanced Asthma Care for Home After the Emergency Room
Recruiting
The investigators propose a randomized controlled trial of Telehealth-Enhanced Asthma Care for Home After the Emergency Room (TEACH-ER) vs. enhanced care (EC). TEACH-ER includes: 1) brief, pictorial, and health literacy-informed asthma education in the ED, with color- and shape-coded labels provided for home asthma medications; 2) virtual primary care follow-up within 1 week of discharge using in-home telemedicine (Zoom) when possible, featuring provider prompts for guideline-based preventive th... Read More
Gender:
ALL
Ages:
Between 3 years and 12 years
Trial Updated:
04/16/2025
Locations: University of Rochester Medical Center, Rochester, New York
Conditions: Asthma in Children
Dietary and Cognitive Effects of Food Ads Posted by TikTok Influencers
Recruiting
Randomized and controlled experimental study to evaluate how influencer food ads on TikTok affect calorie purchases among youth (ages 10-13). Participants will be randomized to one of two conditions: (1) seeing an influencer with food or (2) seeing an influencer without food. Participants will complete a 15-minute survey in which they will be randomized to one of two conditions and view and rate TikTok influencer ads associated with their condition. Then they will complete a food purchasing task... Read More
Gender:
ALL
Ages:
Between 10 years and 13 years
Trial Updated:
04/16/2025
Locations: NYU Langone Health, New York, New York
Conditions: Calorie Consumption
Harm Reduction Services
Recruiting
The purpose of this study is to assess whether an integrated harm reduction intervention (IHRI), compared to harm reduction (HR) services as usual, will improve harm reduction service utilization among Black and Latinx people who use drugs (PWUD).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/16/2025
Locations: NYU Langone Health, New York, New York
Conditions: Drug Use, Substance Abuse, Mental Illness
Neuromodulation and Neuroimaging in Older Children With Mild Traumatic Brain Injury
Recruiting
Mild traumatic brain injury (mTBI) often causes persistent motor and cognitive deficits in children resulting in functional limitations. We are testing a brain stimulation method along with evaluating objective tools to help record and restore communication among affected brain areas, which will facilitate recovery in youth after mTBI.
Gender:
ALL
Ages:
Between 10 years and 15 years
Trial Updated:
04/16/2025
Locations: Ghazala Saleem, Buffalo, New York
Conditions: Brain Concussion, Mild Traumatic Brain Injury, Motor Disorders, Cognitive Impairment
Tablet-based Mobile Health Ultrasound for Point-of-care Breast Cancer Diagnosis in Nigeria (Mobile Health: Technology and Outcomes in Low and Middle-Income Countries)
Recruiting
The purpose of this study is to train Nigerian radiologists to perform ultrasound-guided breast biopsies. Researchers will use mHealth devices to create a sustainable and practical way of training radiologists in Nigeria to perform and clinically implement US-guided breast biopsies into their practice.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/16/2025
Locations: Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York, New York
Conditions: Breast Cancer, Breast Cancer Female
Phase 3, Double-blind, Randomized, Placebo-controlled Trial to Evaluate the Efficacy and Safety of AR1001 in Participants With Early Alzheimer's Disease (Polaris-AD)
Recruiting
This AR1001-ADP3-US01 protocol is a double-blind, randomized, placebo-controlled, multi- center, parallel-group comparison pivotal Phase 3 study to evaluate the efficacy and safety of AR1001 for the treatment of participants with early AD.
Gender:
ALL
Ages:
Between 55 years and 90 years
Trial Updated:
04/16/2025
Locations: Dent Neuroscience Research Center, Amherst, New York
Conditions: Alzheimer Disease
Working With Doctors and Pharmacists to Help Parents Give Children's Liquid Medicines Safely
Recruiting
The study objective is to assess the impact of an automated electronic health record (EHR)-based intervention that leverages e-prescriptions to support pharmacist adherence to recommended dispensing practices, with the goal of reducing parent dosing errors. Specifically, the study aims are to: 1) Examine the efficacy of the EHR-based intervention in improving pharmacy dispensing practices, including a) adherence to mL-only dosing and b) provision of optimal dosing tools; 2) Examine the efficacy... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/16/2025
Locations: NYU Langone Health - Brooklyn, Brooklyn, New York
Conditions: Medication Dosing Error
Longitudinal Oral Microbiome Sampling for BE
Recruiting
This is a longitudinal cohort study to assess the impact of repeated sampling of an oral microbiome signature for Barrett's esophagus (BE). Potential participants will be identified through chart review of patients who have had an endoscopy in the past three years.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/16/2025
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Barrett Esophagus
Couples Lived Experience
Recruiting
This is a longitudinal study with regular quantitative assessments of all participants every six months for 3 years. The quantitative portion of the study will recruit couples, consisting of individuals over the age of 65 who are in a committed relationship. Both members of the couple must be willing to participate at baseline. The assessment is in two parts. In the first part, each member of the couple will be asked the following: demographic information, mental health history, self-reported ph... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
04/16/2025
Locations: NYU Langone Health, New York, New York
Conditions: Alzheimer Disease, Dementia of Alzheimer Type
Phase Ib Study of the Safety of T-DXd and Immunotherapy Agents With and Without Chemotherapy in Advanced or Metastatic HER2+, Non-squamous NSCLC
Recruiting
DESTINY-Lung03 will investigate the safety and tolerability of trastuzumab deruxtecan in combination with Immunotherapy Agents with and without chemotherapy in patients with HER2 over-expressing non-small cell lung cancer. The efficacy will be also analyzed as a secondary endpoint.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/16/2025
Locations: Research Site, Bronx, New York
Conditions: Locally Advanced or Metastatic Non-Small Cell Lung Cancer
A Study of CHeckpoint Inhibitors in Men With prOgressive Metastatic Castrate Resistant Prostate Cancer Characterized by a Mismatch Repair Deficiency or Biallelic CDK12 Inactivation
Recruiting
The primary objective is to assess the activity and efficacy of pembrolizumab, a checkpoint inhibitor, in Veterans with metastatic castration-resistant prostate cancer (mCRPC) characterized by either mismatch repair deficiency (dMMR) or biallelic inactivation of CDK12 (CDK12-/-). The secondary objectives involve determining the frequency with which dMMR and CDK12-/- occur in this patient population, as well as the effects of pembrolizumab on various clinical endpoints (time to PSA progression, m... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
04/16/2025
Locations: James J. Peters VA Medical Center, Bronx, NY, Bronx, New York
Conditions: Metastatic Castration Resistant Prostate Cancer