New York is currently home to 4502 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Study to Evaluate Safety, Efficacy of FF-10832 in Combo With Pembrolizumab in Urothelial & Non-small Cell Lung Cancer
Recruiting
To confirm a recommended Phase 2 dose (RP2D) of FF-10832 (Gemcitabine Liposome Injection) given intravenously Day 1 of a 21-day cycle, in combination with 200 mg pembrolizumab given intravenously Day 1 of the same 21-day cycle, for treatment of advanced urothelial and non-small cell lung cancer
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/09/2025
Locations: NYU Langone Health, New York, New York
Conditions: Advanced Urothelial Carcinoma, Advanced Non Small Cell Lung Cancer
Study of R289 in Patients With Lower-risk Myelodysplastic Syndromes (LR MDS)
Recruiting
Phase 1b Study of R289 in Patients with Lower-risk Myelodysplastic Syndromes (LR MDS)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/09/2025
Locations: Ichan School of Medicine at Mount Sinai, New York, New York
Conditions: Low Risk Myelodysplastic Syndromes
Smartphones for Opiate Addiction Recovery
Recruiting
Treatments for opioid addiction exist, but effectiveness is compromised when subjects use illicit opiates during treatment. Reuse rates during treatment can be high, and reducing illicit opiate use during treatment has thus recently become a major NIDA policy goal. The 5-minute battery indicates the numerical probability that a patient will reuse illicit opiates within the next 7-10 days.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
04/09/2025
Locations: NYU Langone, New York, New York
Conditions: Opioid-use Disorder
Radiation and TSR-042 (Dostarlimab) in People With Endometrial Cancer After They Receive Surgery
Recruiting
This study will test whether the combination of radiation and Dostarlimab is an effective treatment for women with MMR-D/MSI-H endometrial cancer who have recently undergone surgery.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/09/2025
Locations: Memorial Sloan Kettering Commack (All Protocol Activities), Commack, New York
Conditions: Endometrial Cancer
A Study in Participants With Advanced Cancers Associated With Expression of DLL3 (MK-6070-001/HPN328-4001)
Recruiting
This study will investigate the maximum tolerated dose, the recommended dose for expansion (RDE), safety, efficacy, and pharmacokinetics of gocatamig alone, gocatamig with Atezolizumab and gocatamig with I-DXd in participants with advanced cancers associated with expression of Delta-like Canonical Notch Ligand 3 (DLL3).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/09/2025
Locations: Roswell Park Comprehensive Cancer Center, Buffalo, New York
Conditions: Small-cell Lung Cancer, Neuroendocrine Carcinoma
Medtronic Cardiac Surgery PMCF Registry
Recruiting
This registry is being conducted to support ongoing post-market surveillance activities.
Gender:
ALL
Ages:
All
Trial Updated:
04/09/2025
Locations: Mount Sinai Medical Center, New York, New York
Conditions: Valve Disease, Heart
A Study of Pazopanib With or Without Abexinostat in Patients With Locally Advanced or Metastatic Renal Cell Carcinoma (RENAVIV)
Recruiting
This is a randomized, Phase 3, double-blind, placebo-controlled study of pazopanib plus abexinostat versus pazopanib plus placebo in patients with locally advanced unresectable or metastatic renal cell carcinoma (RCC).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/09/2025
Locations: Northwell Health/Monter Cancer Center, Lake Success, New York
Conditions: Renal Cell Carcinoma
Filgrastim-Mobilized Stem Cells for Transplantation Using Unrelated Donors
Recruiting
The purpose of the study is to: * Establish and evaluate a system for collection of filgrastim-mobilized peripheral blood stem cells from National Marrow Donor Program donors (NMDP) donors * Assess the safety among NMDP donors of filgrastim administration and PBSC leukapheresis * Assess the safety and efficacy of filgrastim-mobilized PBSC in unrelated donor hematopoietic stem cell transplant recipients * Determine the acceptability of stem cell donation by filgrastim stimulated apheresis in nor... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
04/09/2025
Locations: DKMS Americas, New York, New York
Conditions: Healthy
Predictors of Pregnancy Outcome in Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS)
Recruiting
The PROMISSE Study is an observational study of 700 pregnant patients, enrolled at nine major clinical centers. The purpose of the study is 1) to determine whether certain proteins (called complement split products) that can injure healthy organs can be used to predict poor pregnancy outcome in patients with systemic lupus erythematosus (SLE) and anti-phospholipid syndrome (APS), and/or 2) to determine whether elevated levels of circulating antiangiogenic factors predict pregnancy complications... Read More
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
04/09/2025
Locations: NYU Langone Medical Center/Hospital for Joint Diseases, New York, New York
Conditions: Systemic Lupus Erythematosus, Antiphospholipid Syndrome
Use of the CA 125 Algorithm for the Early Detection of Ovarian Cancer in Low Risk Women
Recruiting
The goal of this clinical research study is to evaluate a method involving 4 blood tests called CA-125, HE4, HE4 antigen autoantibody complexes, and osteopontin that may be helpful in the early detection of ovarian cancer in women who are at low risk.
Gender:
FEMALE
Ages:
Between 50 years and 74 years
Trial Updated:
04/08/2025
Locations: University of Rochester Medical Center, Rochester, New York
Conditions: Ovarian Cancer
Usefulness and Feasibility of Ultrasound in Office Laryngology Procedures
Recruiting
Investigators will assess the usefulness of using ultrasound in office procedures for laryngology interventions. Participants who qualify will be adults who are undergoing superior laryngeal nerve block, injection laryngoplasty, swallowing evaluation, voice evaluation and voice therapy.
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
04/04/2025
Locations: Weill Cornell Medicine, New York, New York
Conditions: Cough, Vocal Cord Atrophy, Vocal Cord Paresis, Vocal Cord Paralysis, Dysphagia, Dysphonia
A Technology-based Psychosocial Intervention to Support Social Engagement and Well-being in Older Adults With HIV
Recruiting
Older people with HIV (OPH) often live with significant mental health challenges such as social isolation, loneliness, and depression. The objectives of this study are to develop and test the usability and feasibility of a technology-based psychosocial intervention program designed to: enhance social engagement and support; facilitate resource access and education; reduce loneliness; and improve well-being among older adults with HIV who are long-term survivors (diagnosed with HIV ≥ 20 years). T... Read More
Gender:
ALL
Ages:
50 years and above
Trial Updated:
04/04/2025
Locations: Weill Cornell Medicine, New York, New York
Conditions: HIV Diagnosis