New York is currently home to 4503 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Optune for Children With High-Grade Glioma or Ependymoma, and Optune With Radiation Therapy for Children With DIPG
Recruiting
This is a multicenter trial of the Optune device to examine the feasibility and to describe the device-related toxicity in children with supratentorial high grade glioma (HGG) or ependymoma (Stratum 1) and to examine the feasibility and efficacy of concurrent Optune and standard focal radiation therapy (RT) in children with newly diagnosed diffuse intrinsic pontine glioma (DIPG) (Stratum 2).
Gender:
ALL
Ages:
Between 3 years and 21 years
Trial Updated:
04/16/2025
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Malignant Glioma, Ependymoma, Diffuse Intrinsic Pontine Glioma
Tranexamic Acid to Reduce Blood Loss in Spine Surgery
Recruiting
This study is designed to evaluate the efficacy of topical tranexamic acid to reduce perioperative blood loss, reduction in postoperative drain output and allogenic transfusion requirements. The proposed study will be a prospective, randomized, double-blind (subject, surgeons, investigators, research coordinators) placebo-controlled study. Patients requiring posterior spinal fusion will be enrolled for this study. Furthermore, patients undergoing elective complex deformity surgery will also be... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
04/16/2025
Locations: NYP/The Allen Hospital - CUIMC, New York, New York
Conditions: Spinal Injuries, Spinal Deformity
Neural and Psychiatric Consequences of Cannabis Use in Adolescents
Recruiting
The goal of this study is to investigate the effects of cannabis on brain function among adolescents with depression.
Gender:
ALL
Ages:
Between 14 years and 20 years
Trial Updated:
04/15/2025
Locations: Nathan Kline Institute, Orangeburg, New York
Conditions: Cannabis Use, Depression
Evaluating the Safety and Efficacy of Topical Sirolimus 0.2% to Treat Acanthosis Nigricans
Recruiting
The purpose of this study is to demonstrate the safety and efficacy of Sirolimus 0.2% topical gel for patients with Acanthosis Nigricans
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/15/2025
Locations: New York Harbor VA Brooklyn Campus, Brooklyn, New York
Conditions: Acanthosis Nigricans
Effect of Flavored, Carbonated Drinks on Salivary Flow, Salivary Composition, and Taste Perceptions
Recruiting
To determine the effect of flavored, carbonated drinks on salivary flow rate, saliva composition, and taste perceptions compared with control drinks (water, carbonated water, non-carbonated)
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
04/15/2025
Locations: Gatorade Sports Science Institute, Valhalla, New York
Conditions: Taste Perception, Saliva Production
Impact of a Structured Wellness Behavioral Intervention on Quality of Life in NMOSD
Recruiting
This project aims to study whether a structured wellness program intervention can improve quality of life among people living with Neuromyelitis Optica Spectrum Disorder (NMOSD). This pilot will test a multi-modal wellness program tailored to NMOSD patients that includes services from physical therapists, dietitians, social workers, nurse practitioners and cognitive therapists. The trial will be designed as a randomized controlled trial, randomizing patients to immediately starting the program a... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/15/2025
Locations: Corinne Goldsmith Dickinson Center for MS at Mount Sinai, New York, New York
Conditions: Neuromyelitis Optica Spectrum Disorder (NMOSD)
SX-682 in Combination With Carfilzomib, Daratumumab-Hyaluronidase, and Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma
Recruiting
This phase I trial tests the safety and side effects of SX-682 in combination with standard of care treatment carfilzomib, daratumumab-hyaluronidase, and dexamethasone in treating patients with multiple myeloma that has come back after a period of improvement (relapsed) or that has not responded to previous treatment (refractory). SX-682 works by blocking certain sites on cells that suppress the ability of the immune system to destroy tumor cells. Blocking those specific sites allows other cells... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/15/2025
Locations: Roswell Park Comprehensive Cancer Center, Buffalo, New York
Conditions: Recurrent Multiple Myeloma, Refractory Multiple Myeloma
Reiki Breast Surgery QOL Project for Women Undergoing Breast Surgery
Recruiting
This pilot study will examine the impact of pre-operative Medical Reiki© on the psychosocial well-being and recovery of underserved women undergoing breast cancer surgery.
Gender:
FEMALE
Ages:
Between 18 years and 99 years
Trial Updated:
04/15/2025
Locations: Montefiore Medical Center, Bronx, New York
Conditions: Breast Cancer
Efficacy of BNC210 in Acute, As-needed Treatment of Anxiety in Social Anxiety Disorder - 1
Recruiting
The purpose of the study is to evaluate the effect of a single, acute dose of BNC210 compared to placebo on reducing the severity of anxiety provoked by a behavioral assessment task and measured using the Subjective Units of Distress Scale (SUDS) in adult patients with social anxiety disorder.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
04/15/2025
Locations: AFFIRM-1 Study Site, Brooklyn, New York
Conditions: Social Anxiety Disorder
International Study of Cerebral Oxygenation and Electrical Activity During Major Neonatal Surgery
Recruiting
The goal of this observational study is to determine the incidence of perioperative cerebral desaturation in neonates undergoing surgery for congenital malformations. The main questions it aims to answer are: 1. The perioperative factors associated with occurrence of cerebral desaturation 2. The association between perioperative cerebral desaturation, perioperative/hospital outcomes, and physiological conditions. Participants will undergo Near-infrared spectroscopy (NIRS) and electroencephalog... Read More
Gender:
ALL
Ages:
60 weeks and below
Trial Updated:
04/15/2025
Locations: Children's Hospital at Montefiore/Albert Einstein College of Medicine, New York, New York
Conditions: Congenital Disorders, Cerebral Desaturation, Neonatal Surgery
A Single-Arm Phase II Study of Neoadjuvant Intensified Androgen Deprivation (Leuprolide and Abiraterone Acetate) in Combination With AKT Inhibition (Capivasertib) for High-Risk Localized Prostate Cancer With PTEN Loss
Recruiting
The purpose of this study is to learn about how an investigational drug intervention completed before doing prostate surgery (specifically, radical prostatectomy with lymph node dissection) may help in treatment of high risk localized prostate cancers that are most resistant to standard treatments. This is a phase II research study. For this study, capivasertib, the study drug, will be taken with intensified androgen deprivation drugs (iADT; abiraterone and leuprolide) prior to radical prostatec... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
04/15/2025
Locations: James J. Peters VA Medical Center, Bronx, NY, Bronx, New York
Conditions: High-Risk Prostate Cancer
CEM-Plate and CEM-Cage First-In-Human Use Efficacy Study
Recruiting
The study is a prospective, first-in-human, multi-center, non-randomized, single-arm study to assess the safety and efficacy of the CEM-Cage used with the CEM-Plate in patients who are appropriate candidates for a 2-level anterior cervical discectomy and fusion (ACDF). Fifty patients will be enrolled in the study and, after undergoing a 2-level ACDF, will be evaluated at 4 weeks, 3 months, 6 months, 12 months, 18 months, and 24 months.
Gender:
ALL
Ages:
Between 22 years and 79 years
Trial Updated:
04/15/2025
Locations: Albany Medical College, Albany, New York
Conditions: Neck Pain, Spondylosis, Spondylosis With Myelopathy, Spondylosis With Radiculopathy, Spondylosis With Radiculopathy Cervical Region, Intervertebral Disc Disorder Cervical