New York is currently home to 4504 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Upfront Surgical Resection for Osteosarcoma
Recruiting
The goal of this pilot study is to learn about patients with newly diagnosed osteosarcoma of an extremity, and whether surgically removing the tumor prior to the administration of any chemotherapy will improve functional outcomes. In order to learn about the patient's experience, the study team will administer questionnaires to the patient and surgeon at various timepoints to assess recovery and the function of the extremity.
Gender:
ALL
Ages:
Between 5 years and 40 years
Trial Updated:
03/03/2025
Locations: Montefiore Medical Center, Bronx, New York
Conditions: Osteosarcoma
The Effects of an Acute High-intensity Exercise on Heart and Brain Function in People with Spinal Cord Injury
Recruiting
The heart and brain are regulated by the autonomic nervous system. Control of these organs can be disrupted in people with spinal cord injury (SCI). This may affect their ability to regulate blood pressure during daily activities and process the high-level information. Previous studies show that high-intensity exercise induces better outcomes on heart and information processing ability in non-injured people compared to moderate-intensity exercise. However, it is unknown the effects of high-inten... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
03/03/2025
Locations: University at Buffalo, South Campus, Buffalo, New York
Conditions: Autonomic Nervous System Disease, Spinal Cord Injuries, Cognition
Sustained Acoustic Medicine for Symptomatic Treatment of Knee Pain Related to Osteoarthritis
Recruiting
The purpose of this study is to assess the ability of long-duration low intensity therapeutic ultrasound (LITUS) to alleviate knee Osteoarthritis pain over a 24-week period. The primary objective of this study is to evaluate the analgesic effect of LITUS in subjects suffering from knee Osteoarthritis pain. Secondary objectives are to assess the ability of LITUS to improve joint function.
Gender:
ALL
Ages:
Between 50 years and 85 years
Trial Updated:
03/03/2025
Locations: Cayuga Medical Center - Medical Pain Consultants, Dryden, New York
Conditions: Osteo Arthritis Knee, Arthritis
The Role of Neutrophils in the Age-driven Decline in Anti-pneumococcal Vaccine Responses
Recruiting
This study focuses on the role of neutrophils in shaping the adaptive immune response to the anti-pneumococcal vaccine Prevnar-13 in young and elderly adults.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
03/03/2025
Locations: University at Buffalo, Buffalo, New York
Conditions: Aging
Real World Registry for Use of the Ion Endoluminal System
Recruiting
The primary objective of this study is to evaluate the performance of the Ion Endoluminal System with real-world use for pulmonary lesion localization or biopsy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/03/2025
Locations: Mercy Hospital of Buffalo, Buffalo, New York
Conditions: Lung Cancer, Multiple Pulmonary Nodules, Lung Neoplasms, Respiratory Tract Neoplasms, Thoracic Neoplasms, Neoplasms by Site, Neoplasms, Lung Diseases, Respiratory Tract Diseases
Two Fraction Prostate SBRT With DIL SIB
Recruiting
Phase I/Ib, single arm trial of Two-Fraction Stereotactic Body Radiation Therapy (SBRT) with an MRI directed, dominant intraprostatic lesion (DIL), simultaneous integrated boost (SIB) based on genomic classification in the treatment of localized prostate cancer. The primary purpose of this study is to determine the feasibility and safety of two fraction SBRT in patients with localized prostate cancer.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
03/03/2025
Locations: NYU Langone Hospital - Long Island, Mineola, New York
Conditions: Prostate Cancer
A Study of Gilteritinib in Combination With Ivosidenib or Enasidenib in People With Acute Myeloid Leukemia (AML)
Recruiting
The researchers are doing this study to see if the combination of gilteritinib with ivosidenib or enasidenib is a safe and effective treatment for people with relapsed/refractory AML with FLT3/IDH1 or FLT3/IDH2 gene mutations. The researchers will also look for the highest dose of the combination of gilteritinib with ivosidenib or enasidenib that causes few or mild side effects. When the highest safe dose is found, they will test that dose in new groups of participants.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/03/2025
Locations: Memorial Sloan Kettering Suffolk-Commack, Commack, New York
Conditions: Acute Myeloid Leukemia (AML)
Study of Peripheral Arterial Disease (PAD) in People With Cancer Who Will Be Having Surgery
Recruiting
Researchers are studying whether people with risk factors for blood circulation disease have a condition called peripheral arterial disease (PAD). People with PAD have poor blood circulation because of narrowing or blocks in blood vessels caused by fat or calcium deposits (atherosclerosis). The study researchers think that PAD may lead to worse outcomes in cancer treatment, but people with cancer are not routinely tested for the disease. The purpose of this study is to find out how common PAD i... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
03/03/2025
Locations: Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York, New York
Conditions: Peripheral Arterial Disease (PAD) in Cancer Patients
Leveraging Regulatory Flexibility for Methadone Take-Home Dosing to Improve Retention in Treatment for Opioid Use Disorder
Recruiting
Using a stepped-wedge randomized controlled trial, the study will test whether a clinic-level multidimensional intervention conducted in 36 opioid treatment programs (OTPs) will improve clinical decision making, regulatory confusion, legal liability concerns, capacity for clinical practice change, and financial barriers to take- home dosing (THD) for methadone as compared to treatment as usual.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/03/2025
Locations: University at Buffalo, Buffalo, New York
Conditions: Problems Related to Social Environment
A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused Etentamig (ABBV-383) in Combination With Anti-Cancer Regimens for the Treatment of Adult Participants With Relapsed/Refractory Multiple Myeloma
Recruiting
Multiple myeloma (MM) is a plasma cell disease characterized by the growth of clonal plasma cells in the bone marrow. The purpose of this study is to assess the safety and toxicity of etentamig (ABBV-383) when co-administered with pomalidomide-dexamethasone (Pd), lenalidomide-dexamethasone (Rd), or daratumumab-dexamethasone (Dd), in adult participants with relapsed/refractory (R/R) multiple myeloma (MM). Adverse events and change in disease activity will be assessed. Etentamig is an investigati... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/03/2025
Locations: Rutenberg Cancer Center /ID# 244647, New York, New York
Conditions: Relapsed/Refractory Multiple Myeloma
Novel Imaging Technique to Assess Gynecologic Cancer
Recruiting
This study will test a new type of DCE (dynamic contrast-enhanced) MRI (magnetic resonance imaging) to see whether, compared with traditional MRI, it produces better images that provide more information about tumors, which may help doctors make better decisions about treating women who have gynecologic cancer. MRI is commonly used to detect and evaluate many types of cancer, but its slow processing speed and the risk that images will be blurred if the patient moves inside the scanner can limit... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
03/03/2025
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Gynecologic Cancer
Poly-omic Predictors of Symptom Duration and Recovery for Adolescent Concussion
Recruiting
The purpose of this study is to identify changes in salivary micro ribonucleic acid (miRNA) levels that are predictive of symptom duration and character following mild traumatic brain injury (mTBI) in children.
Gender:
ALL
Ages:
Between 13 years and 18 years
Trial Updated:
03/03/2025
Locations: Weill Cornell Medicine/ New York Presbyterian Hospital, New York, New York
Conditions: Concussion, Mild