New York is currently home to 4500 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Craniomaxillofacial and Upper Extremity Allotransplantation
Recruiting
The purpose of this study is to evaluate functional and aesthetic outcomes of combined facial and upper extremity composite tissue allografts on patients who have not achieved functional and aesthetic outcomes with conventional reconstructive surgical strategies and prosthetic devices.
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
01/30/2025
Locations: NYU Langone Health, New York, New York
Conditions: Face Injuries, Hand Injuries, Craniofacial Injuries, Upper Extremity Injuries, Facial Injuries, Facial Deformity
Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma
Recruiting
This is a multicenter, randomized, open label phase lll trial to assess whether preoperative chemotherapy, as an adjunct to curative-intent surgery, improves the prognosis of high risk DDLPS (dedifferentiated Liposarcoma) and LMS (Leiomyosarcoma) patients as measured by disease free survival. After confirmation of eligibility criteria, patients will be randomized to either the standard arm or experimental arm.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/30/2025
Locations: Roswell Park Cancer Institute, Buffalo, New York
Conditions: Retroperitoneal Sarcoma, Liposarcoma, Leiomyosarcoma
A Study of Valemetostat in Combination With Atezolizumab in People With Lung Cancer
Recruiting
This study will test whether valemetostat in combination with atezolizumab is a safe treatment that causes few or mild side effects in people with extensive-stage small cell lung cancer (SCLC). The researchers will test different doses of valemetostat to find the highest dose that causes few or mild side effects in participants. After the dose is found, researchers will test it in a new group of participants to learn more about the safety of the study treatment and see if it is an effective trea... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/29/2025
Locations: Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities), Commack, New York
Conditions: Extensive-stage Small-cell Lung Cancer
A Study of OnCARlytics (CF33-CD19) in Combination with Blinatumomab in Adults with Advanced or Metastatic Solid Tumors (OASIS)
Recruiting
This is an open-label, dose escalation and dose expansion, multi-center phase I study evaluating the safety and tolerability of CF33-CD19 administered intravenously (IV) or intratumorally (IT) in combination with blinatumomab in adults with advanced or metastatic solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/29/2025
Locations: Roswell Park Comprehensive Cancer Center, Buffalo, New York
Conditions: Solid Tumor, Adult
Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)
Recruiting
The main objective of the study is to evaluate the safety, performance and clinical benefits of the Persona implant and its instrumentation in primary total knee arthroplasty
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/29/2025
Locations: Syracuse Orthopaedic Specialists, DeWitt, New York
Conditions: Knee Pain Chronic, Osteoarthritis, Knee, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Varus Deformity, Valgus Deformity, Flexion Deformity of Knee, Avascular Necrosis
NYC Cancer Outreach Network in Neighborhoods for Equity and Community Translation
Recruiting
NYC CONNECT will carry out a randomized controlled trial (RCT) which will assess the relative effectiveness of two evidence-based strategies to increase cancer screening rates for breast, cervical, and colorectal cancer. The RCT will compare the effectiveness of using a combination of 1) culturally and linguistically tailored cancer education materials and 2) community health workers (CHWs) to provide navigation services for cancer screening (the "patient navigation" \[PN\] arm) versus providing... Read More
Gender:
ALL
Ages:
Between 21 years and 75 years
Trial Updated:
01/29/2025
Locations: Albert Einstein College of Medicine, Bronx, New York
Conditions: Cancer Screening
PhytoSERM to Prevent Menopause Associated Decline in Brain Metabolism and Cognition
Recruiting
This is a proof-of-concept phase 2 clinical trial to investigate the safety and effect of the phytoestrogenic supplement PhytoSERM on regional brain metabolism by fluorine-18 fluorodeoxyglucose positron emission tomography (18F-FDG-PET) in peri- and postmenopausal women. The investigators hypothesize that there will be a significant difference between the PhytoSERM group and placebo group in glucose brain metabolism.
Gender:
ALL
Ages:
Between 45 years and 60 years
Trial Updated:
01/29/2025
Locations: The Alzheimer's Prevention Program / Weill Cornell Medicine, New York, New York
Conditions: Menopause, Cognitive Change, Brain Disorder, Metabolic
Mechanisms of Resistance to PSMA Radioligand Therapy
Recruiting
This is a multicenter, correlative study to existing Lutetium based prostate-specific membrane antigen (PSMA)-targeted radioligand therapy (RLT) trials and uses.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/29/2025
Locations: Memorial Sloan Kettering, New York, New York
Conditions: Prostate Cancer
taVNS on Pupillary Response and Perceptual Learning
Recruiting
This study has two parts. The study team will evaluate transcutaneous auricular vagal nerve stimulation (taVNS) and two sham settings during a passive task while measuring pupillary response. Second, the study team will assign either taVNS, sham, or no intervention during a go/no-go task and evaluate perceptual learning over three sessions which will also include measuring the pupillary response and electroencephalogram (EEG).
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/29/2025
Locations: NYU Langone Health - Bellevue Hospital, New York, New York
Conditions: Pupillary Response
BRInging the Diabetes Prevention Program to GEriatric Populations
Recruiting
Over 24 million Americans are over 65 years and have prediabetes. Prediabetes can be addressed using a public health approach: among the 20% of participants in the Diabetes Prevention Program (DPP) who were ages 60 and over, the diet and physical activity intervention conferred a 71% risk reduction of diabetes after an average follow-up of 3 years. The population of older adults is projected to more than double from 52.5 million in 2019 to \~100 million by 2060, and if projections hold, about ha... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
01/29/2025
Locations: NYU Langone Health, New York, New York
Conditions: Pre Diabetes
Use of Artificial Intelligence for Clinical Assessment of Assisted Reproductive Techniques and IVF Outcomes
Recruiting
The use of machine learning techniques using an artificial intelligence tool is proposed to analyze clinical data to predict best possible IVF/ART outcomes. This tool has been utilized to accurately predict embryo quality here at Cornell. Utilizing this tool to assess objective clinical findings and predict outcomes of assisted reproductive techniques is sought, with the ultimate goal of an automated tool to reduce implicit physician bias. Within this goal, using this tool to objectively and acc... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
01/29/2025
Locations: Weill Cornell Medicine, New York, New York
Conditions: Infertility, in Vitro Fertilization (IVF), ART
Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery
Recruiting
This is a multi center, Phase I, Phase II and surgical study of the CX-4945 drug (silmitasertib sodium) for patients with recurrent SHH (Sonic Hedgehog) medulloblastoma
Gender:
ALL
Ages:
3 years and above
Trial Updated:
01/29/2025
Locations: Memorial Sloan-Kettering Cancer Center, New York, New York
Conditions: Medulloblastoma, Childhood, Medulloblastoma Recurrent, Medulloblastoma