New York is currently home to 4503 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer
Recruiting
This phase III trial compares the effects of shorter chemotherapy (chemo)-immunotherapy without anthracyclines to usual chemo-immunotherapy for the treatment of early-stage triple negative breast cancer. Paclitaxel is in a class of medications called anti-microtubule agents. It stops cancer cells from growing and dividing and may kill them. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be bette... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/29/2024
Locations: Glens Falls Hospital, Glens Falls, New York
Conditions: Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8, Early Stage Triple-Negative Breast Carcinoma
Enhanced Nutritional Optimization in LVAD Trial
Recruiting
The goal of this clinical trial is to assess whether a peri-operative intervention with nutritional immune modulating intervention (Ensure Surgery Immunonutrition shake) has beneficial effects on the complex interplay between gut microbiome, systemic inflammation and malnutrition that is commonly present in advanced heart failure and the adverse events associated with left ventricular assist device (LVAD) placement in hospitalized advanced heart failure patients awaiting LVAD implantation. The m... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/29/2024
Locations: Columbia University Medical Center, New York, New York
Conditions: Heart Failure, Gut Microbiome, Nutritional Deficiency
Polatuzumab Vedotin in Combination With Chemotherapy in Subjects With Richter's Transformation
Recruiting
This study evaluates the effectiveness and safety of Polatuzumab vedotin plus infusional chemoimmunotherapy containing rituximab, etoposide, prednisone, cyclophosphamide and hydroxydaunorubicin. This is a single arm study. Enrolled patients will receive up to six cycles (21-day cycles) of therapy. While on study, subjects will be monitored weekly until end of treatment, then followed for 52 weeks or until disease progression or discontinuation due to toxicity or death. After completion of the 52... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/29/2024
Locations: Mount Sinai- Icahn School of Medicine, New York, New York
Conditions: Richter Syndrome, Chronic Lymphocytic Leukemia
Clinical Evaluation of Frequency Allocation for Bimodal CI Users
Recruiting
This study will examine experienced, bimodal cochlear implant (CI) patients who receive an alternative frequency allocation table (FAT) to determine how it improves sound quality, device satisfaction, and speech perception abilities with respect to the standard default FAT. The goal of this study is to investigate how improving place-pitch mismatch in bimodal CI users affects 1) sound quality, 2) satisfaction, and 3) speech perception.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/28/2024
Locations: NYU Langone Health, New York, New York
Conditions: Hearing Impairment
Enhancing Access to Supportive Services for Women of Color with Metastatic Breast Cancer
Recruiting
Black and Latina women experience disparities in supportive and palliative care access and outcomes. The goal of the proposed pilot study is to evaluate the feasibility and acceptability of a community navigator delivered supportive care intervention for historically underserved populations of women with metastatic breast cancer.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
10/28/2024
Locations: Mount Sinai Hospital, New York, New York
Conditions: Metastatic Breast Cancer, Stage IV Breast Cancer AJCC V7
Oral Nutritional Optimization in Total Joint Arthroplasty
Recruiting
The purpose of this study is to determine the effect on hematological markers of nutritional intervention on nutritionally deficient patients following total joint replacement surgery.
Gender:
ALL
Ages:
55 years and above
Trial Updated:
10/28/2024
Locations: NYU Langone Health, New York, New York
Conditions: Osteoarthritis
Natural History Study - Mitochondrial Disease
Recruiting
Carriers of the m.3242A\>G mutation often have clinical symptoms which can include migraines, seizures, strokes, hearing loss, balance issues, gastrointestinal issues, and many other symptoms. The investigators would like to learn more about these disorders and have designed a "Natural History Study" to monitor these conditions over time so that physicians and scientists can not only understand the problems that patients have, but work on developing treatments. The focus of the current work is t... Read More
Gender:
ALL
Ages:
4 years and above
Trial Updated:
10/28/2024
Locations: Columbia University, New York, New York
Conditions: MELAS or m.3243 A>G Mitochondrial DNA Mutation Carrier
Autologous Hair Follicle Derived Secretome as Adjunct to Aesthetic Procedures
Recruiting
Non-interventional, multi-site, prospective, open-label, observational, real-world study of autologous hair follicle secretome use.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
10/25/2024
Locations: Luxurgery, New York, New York
Conditions: Post Procedural Erythema
Testing the Role of Anti-fungal Therapy in Improving the Response to Therapies for Crohn's Disease
Recruiting
The goal of this clinical trial is to learn about the effects of fluconazole in patients who plan to start or are currently undergoing standard of care treatment and plan to dose-escalate an IL-23 therapy for their Crohn's disease. The main question it aims to assess is whether or not patient response to IL-23 therapies improve when simultaneously treated with fluconazole.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/24/2024
Locations: Weill Cornell Medicine, New York, New York
Conditions: Crohn's Disease, Inflammatory Bowel Diseases
PUSH-IT Continuing Enteral Feeds for Tracheostomy
Recruiting
The goal of this clinical trial is to evaluate nutrition administration in the time around the tracheostomy in patients with breathing tubes. The main questions it aims to answer are: * Will continuing nutrition up to the time of surgery (tracheostomy) decrease nutrition interruptions, thereby increasing food intake? * Does continuing nutrition up to the time of surgery increase instances of food going into the lungs or lung infections? Researchers will compare patients who have nutrition with... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/24/2024
Locations: Erie County Medical Center (University at Buffalo), Buffalo, New York
Conditions: Tracheostomy Complication, Critical Illness, Nutritional Deficiency
Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI
Recruiting
The study is a randomized trial of two different screening methods for early detection of liver cancer in patients with cirrhosis of the liver. The goal of PREMIUM is to compare an abbreviated version of the diagnostic gold standard for HCC (aMRI) +AFP to the standard-of-care screening (US+AFP) in patients at high risk of developing HCC. The investigators hypothesize that HCC will be detected at earlier stages, allowing for more curative treatments and resulting in a reduction in HCC-related mor... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
10/24/2024
Locations: James J. Peters VA Medical Center, Bronx, NY, Bronx, New York
Conditions: Carcinoma, Hepatocellular, Cirrhosis
Longitudinal Study of Neurogenetic Disorders
Recruiting
The purpose of this study is to analyze patterns in individuals with hnRNP (and other) genetic variants, including their neurological comorbidities, other medical problems and any treatment. The investigators will maintain an ongoing database of medical data that is otherwise being collected for routine medical care. The investigators will also collect data prospectively in the form of questionnaires, neuropsychological assessments, motor assessments, and electroencephalography to examine the la... Read More
Gender:
ALL
Ages:
All
Trial Updated:
10/24/2024
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Neurodevelopmental Disorders, Intellectual Disability, Developmental Delay, Autism Spectrum Disorder, Seizures, Hypertonia, Muscle, Hypotonia