New York is currently home to 4476 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Longitudinal Cortical Demyelination in Multiple Sclerosis and Related Disorders
Recruiting
In this protocol, a combination of MRI, blood, and cerebrospinal fluid (CSF) analysis will be used to understand the natural history, underlying immunologic mechanisms, and clinical implications of central nervous system (CNS) lesions, in particular lesions in the cerebral cortex, in multiple sclerosis (MS) and other inflammatory and autoimmune disorders affecting the CNS. Patients with these disorders, as well as healthy controls, will undergo baseline clinical evaluation and testing, bloodwork... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/27/2024
Locations: Mount Sinai Hospital, New York, New York
Conditions: Multiple Sclerosis, Neuromyelitis Optica, Demyelinating Autoimmune Diseases, CNS
Postpartum Low-Dose Aspirin and Preeclampsia
Recruiting
The purpose of this research study is to find out whether women with severe preeclampsia taking low-dose aspirin (LDA) for 3 weeks post-delivery will experience an improvement in endothelial function (measured as flow-mediated dilation - FMD) and severity of disease, as the effects of preeclampsia can persist postpartum. Women diagnosed with severe preeclampsia prior to delivery will be enrolled and randomized to receive either low-dose aspirin (81mg) or placebo to take daily for up to 3 weeks p... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
06/27/2024
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Preeclampsia Postpartum
Evaluation and Optimization of Ultrasound and/or MRI Hardware and Software
Recruiting
The purpose of this study is to evaluate and optimize ultrasound and/or MRI hardware and software in both existing ultrasound/MRI units as well as in newly installed commercially available ultrasound/MRI units. The study also serves to familiarize the ultrasound/MRI technician staff with how to operate newly installed software sequences or hardware. The information obtained from this study will be utilized to optimize new software sequences and hardware that have been installed on the UMU ultras... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
06/27/2024
Locations: SUNY Upstate Medical University, Syracuse, New York
Conditions: Healthy
Effectiveness of Task Specific Home Exercise Program
Recruiting
The purpose of this study is to compare the effectiveness of 2 different types of Home Exercise Programs (HEP) on mobility in persons with Multiple Sclerosis (MS). Specifically, we will be comparing the Standard of Care (SOC) a program based on aerobic conditioning and calisthenics to a Task Specific Program (TSP). Primary Question: Will persons with who receive a Task Specific HEP have greater improvement in mobility than those who receive the SOC? Secondary question: Will a task specific HEP... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
06/26/2024
Locations: New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, New York
Conditions: Multiple Sclerosis
Venetoclax-Dexamethasone in Relapsed and/or Refractory t(11;14) Amyloidosis
Recruiting
The purpose of this study is assess safety, safest dose, and effectiveness of venetoclax in combination with dexamethasone in participants with t(11;14) positive relapsed (comes back) or refractory (did not get better) light chain amyloidosis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/26/2024
Locations: New York Presbyterian Hospital/Columbia University Irving Medical Center, New York, New York
Conditions: AL Amyloidosis
MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
Recruiting
The FLEX Registry will be implemented to operate as a large-scale, population based, prospective registry. All patients with stage I to III breast cancer who receive MammaPrint® and BluePrint testing on a primary breast tumor are eligible for entry into the FLEX Registry, which is intended to enable additional study arms at low incremental effort and cost. FLEX Registry will utilize an adaptive design, where additional targeted substudies and arms can be added after the initial study is opened.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/26/2024
Locations: New York Oncology Hematology, Albany, New York
Conditions: Breast Cancer
InterNatIonal CHildhood Leukemia Microbiome/MEtabolome Cohort
Recruiting
Nutritional status is a measurable and modifiable factor that is often not considered during treatment and its clinical impact undervalued due in part to the heavy demands on clinicians in low and middle income countries to deliver therapy to large numbers of patients. The proposed study will create a biobank of clinical data and biological specimens which will foster future studies on cancer progression and prognosis as well as toxicities during treatment which may impact survivorship and late-... Read More
Gender:
ALL
Ages:
Between 3 years and 18 years
Trial Updated:
06/25/2024
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Acute Lymphoblastic Leukemia, Nutrition Aspect of Cancer, Microtia, Genetic Predisposition
Decision Aid (DA) for Renal Patients
Recruiting
The objective of this study is to understand how patients make decisions about treating their kidney masses, and to identify key values and preferences for treating their kidney masses. The study team will develop a decision aid (DA) using the decision-analytic model to communicate personalized benefit/harm estimates to patients and promote patient-centered treatment of renal tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/25/2024
Locations: NYU Langone Health, New York, New York
Conditions: Kidney Tumor, Renal Cancer
A Study of Changes in Heart Function and Blood Flow in People Receiving Anesthesia
Recruiting
The purpose of this study is to understand changes in heart function (how the heart pumps blood) and blood flow in people who receive general anesthesia during surgery. The researchers are particularly interested in the heart function and blood flow changes in people who experience low blood pressure (hypotension) after receiving anesthesia.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/24/2024
Locations: Memorial Sloan Kettering Cancer Center (All protocol activites), New York, New York
Conditions: Anesthesia
taVNS for FRNS in Children
Recruiting
Children with frequently relapsing nephrotic syndrome (FRNS) are exposed to prolonged courses of steroids and other immunosuppressant medications. Given the adverse side effect profiles and variable efficacy of these medications, there is an urgent need to identify novel and safe therapies to treat nephrotic syndrome in children. Stimulation of the vagus nerve, which can be activated non invasively by transcutaneous auricular vagus nerve stimulation (taVNS), has immunomodulatory effects mediated... Read More
Gender:
ALL
Ages:
Between 3 years and 17 years
Trial Updated:
06/24/2024
Locations: Cohen Children's Medical Center, New Hyde Park, New York
Conditions: Nephrotic Syndrome in Children, Minimal Change Disease, Focal Segmental Glomerulosclerosis
A Pilot Trial of taVNS for SRNS in Children (kidNEY-VNS)
Recruiting
Children with steroid resistant nephrotic syndrome (SRNS) are exposed to prolonged courses of immunosuppressant medications. Given the adverse side effect profiles and variable efficacy of these medications, there is an urgent need to identify novel and safe therapies to treat nephrotic syndrome in children. Stimulation of the vagus nerve, which can be activated noninvasively by transcutaneous auricular vagus nerve stimulation (taVNS), has immunomodulatory effects mediated by the inflammatory re... Read More
Gender:
ALL
Ages:
Between 3 years and 17 years
Trial Updated:
06/24/2024
Locations: Cohen Children's Medical Center, New Hyde Park, New York
Conditions: Nephrotic Syndrome in Children, Minimal Change Disease, Focal Segmental Glomerulosclerosis
Registry of Asthma Characterization and Recruitment 3 (RACR3)
Recruiting
This is a multi-center, non-interventional registry to create and maintain a database of participants to serve as a recruitment source for current and future DAIT NIAID-sponsored Childhood Asthma in Urban Settings (CAUSE) studies.
Gender:
ALL
Ages:
All
Trial Updated:
06/24/2024
Locations: Icahn School of Medicine at Mount Sinai: Division of Clinical Immunology, Immunology Institute, New York, New York
Conditions: Asthma