New York is currently home to 4476 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Effects of MK-3475 (Pembrolizumab) on the Breast Tumor Microenvironment in Triple Negative Breast Cancer
Recruiting
Assess response to pembrolizumab in both primary tumor, normal breast stroma, circulating lymphocytes and serum exosomes in treatment naive triple negative breast cancer (TNBC) patients. Assess for change in tumor-infiltrating lymphocytes (TILS) both stromal (sTILS) and intraepithelial (iTILS) in newly diagnosed early stage TNBC patients treated with two doses of MK-3475 prior to lumpectomy.
Gender:
FEMALE
Ages:
Between 21 years and 80 years
Trial Updated:
06/17/2024
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Triple Negative Breast Cancer
The Effect of Omega-3 Fortified Smoothies on Omega-3 Index and Physical Performance Related Outcomes Among Soldiers
Recruiting
The goal of this clinical trial is to test the effect of omega-3 on physical performance and recovery of Soldiers. Objectives 1: Assess the impact of 8-weeks of daily consumption of 1600mg of omega-3 fortified smoothie on O3I response. Objective 2: Determine the relationship between O3I and measures of performance and recovery. Participants will: * Be randomly assigned to placebo group or to the omega-3 fortified smoothie group. * The intervention group will take omega-3 fortified smoothies... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
06/14/2024
Locations: Fort Drum, Fort Drum, New York
Conditions: Nutrition, Healthy
MTC Versus FMT in for RCDI
Recruiting
Investigating four different treatment of MTC or FMT
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/14/2024
Locations: Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: Clostridiodies Difficile Infections
Metabolically Optimized, Non-cytotoxic Low Dose Weekly Decitabine/Venetoclax in MDS and AML
Recruiting
Myeloid malignancies which include AML (acute myeloid leukemia) and MDS (myelodysplatic syndrome) are cancers of the bone marrow which lead to bone marrow failure. The bone marrow is the place or factory in the body where components of blood such as red cells, platelets and white cells are made. In bone marrow failure, the ability of the bone marrow to make these cells is decreased. The decreased bone marrow function is the result from abnormalities that develop in the malignant cells which prev... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/14/2024
Locations: Montefiore Medical Center, Bronx, New York
Conditions: MDS, AML, CMML
EXHIT ENTRE Implementation Trial of High Intensity Versus Low Intensity Strategy
Recruiting
This study is a multi-site, cluster randomized, two group implementation trial comparing a low- versus high-intensity implementation strategy for supporting hospital-based opioid use disorder treatment (HBOT) in community hospital settings where medication for opioid use disorder (MOUD) treatment has not been implemented.
Gender:
ALL
Ages:
All
Trial Updated:
06/14/2024
Locations: New York University, New York, New York
Conditions: Substance Use Disorders, Opioid Use Disorder, Severe, Opioid Use Disorder, Moderate
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
Recruiting
PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study. Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study conducted in community-dwelling older adults without cardiovascular disease (CVD) or dementia will demonstrate the benefit of statins for reducing the primary composite of death, dementia, and persistent disability and secondary composites including mild cognitive impairment (MCI) and cardiovascular events.
Gender:
ALL
Ages:
75 years and above
Trial Updated:
06/14/2024
Locations: Albert Einstein College of Medicine, Bronx, New York
Conditions: Cognitive Impairment, Mild, Dementia, Cardiovascular Diseases
Robotic-Assisted da Vinci System Prophylactic Nipple-Sparing Mastectomy
Recruiting
This study evaluates the safety and effectiveness of the da Vinci Surgical Systems in prophylactic Nipple Sparing Mastectomy procedures.
Gender:
FEMALE
Ages:
Between 18 years and 80 years
Trial Updated:
06/14/2024
Locations: Northwell Health, New Hyde Park, New York
Conditions: Nipple Sparing Mastectomy
Blood Collection Biorepository for Liver Disease Research
Recruiting
The purpose of establishing a biorepository is to provide high quality specimens (serum, plasma, buffy coat and liver tissue) for future researchers who are studying the effects that fatty liver and viral diseases have on the liver.
Gender:
ALL
Ages:
7 years and above
Trial Updated:
06/14/2024
Locations: University at Buffalo, Buffalo General Medical Center, Buffalo, New York
Conditions: Non-Alcoholic Steatohepatitis(NASH), Hepatitis C, Hepatitis B, Fibrosis, Cirrhosis, Fatty Liver, Obesity, Childhood, Bariatric Surgery Candidate
Vivistim Registry for Paired VNS Therapy (GRASP)
Recruiting
The purpose of the Vivistim Registry for Paired VNS Therapy (GRASP) is to gather real-world information on patients with arm and hand deficits post-stroke who are considering Vivistim System treatment. Before and after Vivistim System implant, patient data will be collected and reported throughout the therapy process. Physicians or sites will receive appropriate remuneration for the effort and cost involved in collecting and transmitting this data to MicroTransponder Inc.
Gender:
ALL
Ages:
22 years and above
Trial Updated:
06/13/2024
Locations: Mt. Sinai, New York, New York
Conditions: Upper Extremity Problem
Rehabilitation of Airway Protection in Parkinson's Disease
Recruiting
Airway protective disorders are a prevalent and progressive consequence of Parkinson's Disease (PD), and often result in aspiration pneumonia which is the leading cause of death in PD. Despite this, a large number of patients with PD do not access specialized services to address these critical deficits. The investigators will examine the comparative effectiveness of a novel treatment paradigm delivered in-person versus via telehealth in persons with PD, as well as the role of patient burden and... Read More
Gender:
ALL
Ages:
Between 50 years and 90 years
Trial Updated:
06/12/2024
Locations: Teachers College, Columbia University, New York, New York
Conditions: Parkinson Disease, Dysphagia
Abaloparatide vs. Placebo in Post-Menopausal Women and Abaloparatide in Men Receiving Initial Spinal Fusion Surgery
Recruiting
This is a prospective randomized, double-blinded, placebo-controlled, phase 2, 12-month pilot to study the efficacy of abaloparatide in postmenopausal women needing lumbar spinal fusion surgery. A total of 72 women with low bone mass who are scheduled to undergo spinal fusion surgery will be randomized 2:1 in a blinded fashion to receive either 80 mcg of abaloparatide subcutaneously (SC) every day or an identical-appearing placebo SC for 6 months. As well as a total of 24 men in an open-label de... Read More
Gender:
ALL
Ages:
50 years and above
Trial Updated:
06/12/2024
Locations: Hospital for Special Surgery, New York, New York
Conditions: Spinal Fusion
Alpha-Defensin and Synovial Proteins to Improve Detection of Pediatric Septic Arthritis
Recruiting
Differentiating between septic arthritis and other causes of joint inflammation in pediatric patients is challenging and of the utmost importance because septic arthritis requires surgical debridement as part of the treatment regimen. The current gold standard to diagnose septic arthritis in children is a positive synovial fluid culture; however, joint cultures may take several days to return. If a bacterial infection is present, it requires immediate surgical intervention in order to prevent la... Read More
Gender:
ALL
Ages:
17 years and below
Trial Updated:
06/12/2024
Locations: Hospital for Special Surgery, New York, New York
Conditions: Joint Infection, Infection of Hip Joint (Disorder), Infection of Shoulder Joint, Septic Arthritis