New York is currently home to 4507 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
AWARE: Management of ADHD in Autism Spectrum Disorder
Recruiting
This study is a pragmatic clinical trial examining the comparative effectiveness of two stimulant medications (methylphenidate and amphetamine) in the treatment of ADHD in children and adolescents with autism. Using a sequential, multiple assignment randomization trial (SMART) design the study will not only assess these two medications but also the role of an increasingly popular class of ADHD medication, the alpha-2 agonists. Findings from this study will help improve clinicians' approach to me... Read More
Gender:
ALL
Ages:
Between 4 years and 17 years
Trial Updated:
08/07/2024
Locations: University of Rochester, Rochester, New York
Conditions: ADHD, Autism Spectrum Disorder
Evaluating the Effects of a Synbiotic Versus Probiotic or Placebo on Gut Microbiota and Cardiometabolic Health: A Randomized Double-Blind Placebo Controlled Trial
Recruiting
Accordingly, the purpose of this study is to evaluate the efficacy of 1) supplementation with Synbiotic (Plexus® Triplex), 2) commercially-available Probiotic, or 3) placebo control over 30 days on the gut microbiome, cardiometabolic health, body weight and body composition in healthy individuals.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
08/06/2024
Locations: Skidmore College, Saratoga Springs, New York
Conditions: Blood Pressure, Body Composition, Immune Function
Rectus Sheath Block in Cardiac Surgery
Recruiting
This is a prospective, randomized study. The purpose of this study is to evaluate the effect of post-surgical pain control of a type of peripheral nerve block, Rectus Sheath Block. 1. Does the rectus sheath block decrease opioid consumption postoperatively after cardiac surgery? 2. Does the rectus sheath block decrease VAS pain scores postoperatively after cardiac surgery? Study participants will be assigned to receive either rectus sheath block or no block.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
08/06/2024
Locations: Mount Sinai Morningside Hospital Center, New York, New York
Conditions: Cardiac Disease, Postoperative Pain
ABTECT - Maintenance
Recruiting
This is a multicenter, randomized, placebo-controlled study to evaluate the long-term efficacy and safety of ABX464 50mg and 25mg administered once daily (QD) as maintenance therapy in subjects with moderately to severely active ulcerative colitis who have inadequate response, no response, a loss of response, or an intolerance to either conventional therapies \[corticosteroids, immunosuppressant (i.e. azathioprine, 6-mercaptopurine, methotrexate)\] and/or advanced therapies \[biologics (TNF inhi... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
08/06/2024
Locations: NY Scientific Corp., Brooklyn, New York
Conditions: Ulcerative Colitis
Stimulant vs. Non-stimulant Treatments and Reward Processing in Drug-naive Youth at SUD Risk
Recruiting
The study team will examine the effects of FDA approved stimulant and non-stimulant medications for ADHD, among youth with ADHD and with and without Oppositional Defiant Disorder (ODD) or Conduct Disorder (CD), on reward systems of the brain using fMRI.
Gender:
ALL
Ages:
Between 7 years and 12 years
Trial Updated:
08/06/2024
Locations: Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: ADHD, Attention Deficit Hyperactivity Disorder
Carboxylesterase 1 Genetic Variation and Methylphenidate in ADHD
Recruiting
The study team will determine the association between d,l-methylphenidate (MPH) therapeutic outcomes in ADHD patients and genetic variants of CES1 and reveal key associations between CES1 genotypes and the PK and PD of MPH.
Gender:
ALL
Ages:
Between 6 years and 17 years
Trial Updated:
08/06/2024
Locations: Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: ADHD, Attention Deficit Hyperactivity Disorder
Home Rehabilitation Improves Cardiac Effort in Pulmonary Arterial Hypertension
Recruiting
The purpose of this study is to evaluate whether a home rehabilitation program for patients diagnosed with Pulmonary Arterial Hypertension (PAH) will decrease Cardiac Effort (number of heart beats used during 6-minute walk test/walk distance) and improve quality of life. Ultimately, this information could help improve the management of patients with PAH.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/05/2024
Locations: University of Rochester Medical Center, Rochester, New York
Conditions: Pulmonary Arterial Hypertension PAH
Physical Activity: Feasibility Study
Recruiting
The Physical Activity Self-efficacy (PAS) intervention is a web-based behavioral intervention newly developed to promote physical activity in adults with obesity. The conceptual framework for the PAS intervention is based on self-efficacy theory. The objective of this study is to investigate the feasibility and acceptability of implementing the PAS online intervention for adults with obesity recruited from a local weight management center in the United States of America (USA). The study design i... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
08/05/2024
Locations: Guthrie, Binghamton, New York
Conditions: Obesity, Physical Activity, Self-efficacy, Online Intervention, Accelerometers
Effects Of Osteopathic Manipulative Medicine(OMM) On Lower Extremity Muscle Characteristics In Parkinson's Disease(PD) Patients
Recruiting
The purpose of the study is to investigate the effects that Osteopathic Manipulative Medicine has on lower extremity muscle characteristics in PD. Muscle stiffness, range of motion, and gait will be measured. Participants will be asked to attend one in person session at the NYIT Academic Health Care Center. Participants will be randomly assigned to a control or experimental group. After a visit with the treating physician, both groups will have muscle stiffness tested using a myotonometry meter... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/05/2024
Locations: NYIT College of Osteopathic Medicine, Old Westbury, New York
Conditions: Parkinson Disease, Osteopathy in Diseases Classified Elsewhere
Pharmacological Agents for Chronic Spinal Cord Injury (SCI)
Recruiting
The purpose of this study is to investigate the short-term effects of 3 approved FDA drugs (cyproheptadine (CPH), carbidopa-levodopa (CD-LD), and atomoxetine (ATX)) on motor responses when delivered in combination with hand training exercises in people with chronic spinal cord injury. The goal is to learn how to better strengthen connections between the brain and spinal cord after spinal cord injury, and if this connection is improved by one(or more) of the drugs. Multiple aspects of nerve trans... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
08/05/2024
Locations: James J. Peters Veterans Affairs Medical Center, Bronx, New York
Conditions: Spinal Cord Injuries
PROMISE Registry: A Prostate Cancer Registry of Outcomes and Germline Mutations for Improved Survival and Treatment Effectiveness
Recruiting
PROMISE aims to create a comprehensive nationwide registry of prostate cancer patients with germline pathogenic variants by prospectively screening approximately 5,000 subjects with a confirmed prostate cancer diagnosis, either through tissue biopsy, PSA greater than 100 ng/dL and/or radiographic evidence of disease and receiving systemic therapy for prostate cancer. Patients at all stages of disease will be welcome to participate in the PROMISE Registry. Participants will be recruited \& scree... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
08/05/2024
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Prostate Cancer
Efficacy of Osteopathic Manipulative Medicine (OMM) and Phototherapy for Patients With Chronic Lower Back Pain
Recruiting
The purpose of the research study entitled "Efficacy of Osteopathic Manipulative Medicine (OMM) and Phototherapy for Patients with Chronic Lower Back Pain" is to investigate the hypothesis that combined treatment with both osteopathic manipulative medicine (OMM) and phototherapy will provide greater pain relief for patients with chronic lower back pain, as compared with standard medical management or either treatment alone.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
08/05/2024
Locations: New York Institute of Technology, Old Westbury, New York
Conditions: Chronic Lower Back Pain