New York is currently home to 4503 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Venetoclax Plus Intensive Chemotherapy in AML and Advanced MDS
Recruiting
This is a Phase 1b, open-label study evaluating Venetoclax in combination with intensive induction and consolidation chemotherapy in previously untreated, adult patients with acute myeloid leukemia. In Part 1, the dose escalation phase, the safety and tolerability of the combination with Venetoclax at different doses and duration will inform the appropriate dose(s) and regimen(s) for Part 2. In Part 2, the dose expansion phase, a maximum of 28 additional patients will be randomized 1:1 to the MT... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
07/31/2024
Locations: Montefiore Einstein Cancer Center, Bronx, New York
Conditions: Acute Myeloid Leukemia, Myelodysplastic Syndromes
Medical Residents Learning Weight Management Counseling Skills
Recruiting
The goal of this study is to addresses the lack of weight management training physicians receive during their residency training. The main questions it aims to answer are: * How affective is the MRWeight curriculum at increasing medical residents weight management counseling (WMC) skills. * Evaluate residents' adoption of WMC skills in encounters with their patients * what would be the best way to get residents to adopt the WMC skills Residents in the comparison group will receive a course on o... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/30/2024
Locations: Albert Einstein College of Medicine, Bronx, New York
Conditions: Weight Management, Patient Counseling, Video Communication Asssessments
Efficacy of the Dreem 3S Ambulatory Sleep Monitoring Device for the Evaluation of Narcolepsy
Recruiting
This study intends to examine the utility of a home-use EEG-based sleep monitor for the diagnosis and evaluation of disorders of excessive sleepiness, specifically the neurological disorder Narcolepsy Type 1.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/29/2024
Locations: Sleep Insights Medical Associates PLLC, Rochester, New York
Conditions: Narcolepsy Type 1, Hypersomnia, Sleep Disorder
Study of Iadademstat and Gilteritinib in Patients With R/R AML With FMS-like Tyrosine Kinase Mutation (FLT3 Mut+)
Recruiting
Iadademstat is being studied as a treatment for subjects with Relapsed or Refractory Acute Myeloid Leukemia (R/R AML) with FMS-like tyrosine kinase mutation (FLT3 mut+). During the trial, iadademstat will be given in combination with gilteritinib, a drug that is already approved to treat patients with FLT3-mutated R/R AML.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/26/2024
Locations: Icahn School of Medicine at Mount Sinai and Mount Sinai Hospital, New York, New York
Conditions: Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia Refractory
Music Therapy Experiences in Patients With Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD)
Recruiting
This study compares different music therapy (MT) experiences and their impact on memory and language in patients with Alzheimer's disease and Mild Cognitive Impairment. The 12-month study will assess the role of common experiences involving familiar music and other pleasant events (blinded control) to benefit cognition and measure the quality of life for people with Alzheimer's disease and Mild Cognitive Impairment. Following screening, all participants will meet with a licensed music therapis... Read More
Gender:
ALL
Ages:
55 years and above
Trial Updated:
07/26/2024
Locations: Louis Armstrong Center for Music and Medicine, Mount Sinai Beth Israel, New York, New York
Conditions: Alzheimer's Disease, Mild Cognitive Impairment
Impact of Direct Current Electrical Stimulation on Treatment of Lumbosacral Radiculopathy
Recruiting
This study will compare two methods of electrical stimulation (alternating current and direct current) as an adjunctive therapy to treating lumbosacral radiculopathy. Both types of electrical stimulation have been used in clinical practice for physical therapy, however direct current stimulation is much less common and there is less known about its impact on physical therapy outcomes. The aim of this project is to show the efficacy of a novel device, the Neubie direct current device, compared to... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/25/2024
Locations: Hands On Physical Therpay, Astoria, New York
Conditions: Radiculopathy Lumbar, Radiculopathy Sacral, Radiculopathy Multiple Sites
Stick2PrEP Cisgender Women and Trans Individuals
Recruiting
Taking a daily anti-HIV pill can protect people from HIV infection. This is called preexposure prophylaxis \[PrEP\]. Many cisgender women and trans individuals do not know this medication is available; others struggle to take the pill every day. It is important to understand attitudes and preferences about HIV prevention options, especially as new options become available. This study plans to evaluate preferences over time among cisgender women and trans individuals who are taking medication to... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/25/2024
Locations: Columbia University Medical Center, New York, New York
Conditions: HIV Prevention, Pre-exposure Prophylaxis
Efficacy of Non-invasive Vagus Nerve Stimulation for Treatment of Low Weight Eating Disorders
Recruiting
This project includes a 4-week randomized trial comparing pre-meal vagal nerve stimulation (taVNS) to pre-meal sham stimulation. The aims will assess if taVNS results in greater satisfaction, greater calorie consumption, less self-reported fullness, decrease in eating disorder symptoms, and less anxiety than sham stimulation.
Gender:
ALL
Ages:
Between 14 years and 22 years
Trial Updated:
07/24/2024
Locations: Department of Psychiatry, Eating and Weight Disorders Program, New York, New York
Conditions: Anorexia Nervosa
Selinexor (KPT-330) in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
Recruiting
A multicenter, open-label Phase 2b study of selinexor (KPT-330) in participants with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) who have no therapeutic options of demonstrated clinical benefit.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/23/2024
Locations: Clinical Research Alliance, Lake Success, New York
Conditions: Diffuse Large B-cell Lymphoma
Study to Assess Safety of HDP-101 in Patients With Relapsed Refractory Multiple Myeloma
Recruiting
This study will assess the safety, tolerability, pharmacokinetics (PK) and the therapeutic potential of HDP-101 in patients with plasma cell disorders including multiple myeloma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/22/2024
Locations: Mount Sinai, The Tisch Cancer Instutute, New York, New York
Conditions: Multiple Myeloma, Plasma Cell Disorder
Study to Determine the Pharmacokinetics and Pharmacodynamic Effects of Phenylephrine on BP Via IV
Recruiting
The primary objective of this study is to evaluate the dose effect of Phenylephrine Hydrochloride Injection on the treatment of clinically relevant decreased blood pressure in the pediatric population, ≥12 to 16 year old patients undergoing general and neuraxial anesthesia. The secondary objectives are to describe changes in blood pressure and heart rate, time to onset and to maximal response, and the duration of response; to assess the safety of the product in this population; and to character... Read More
Gender:
ALL
Ages:
Between 12 years and 16 years
Trial Updated:
07/22/2024
Locations: Stony Brook Medicine, Stony Brook, New York
Conditions: Hypotension
Evaluation of Outcomes Following In-office Tympanostomy Using the Tula® System: a Prospective, Multi-center Registry
Recruiting
This prospective, single-arm, multicenter registry is being conducted to collect real world post-market data from patients aged from 6 months to 17 years of age who are undergoing an in-office ear tube placement procedure (tympanostomy) using the Tula® System. The Registry will include up to 20 centers in the US and up to 200 patients for the initial evaluation. The FDA-approved Tula System includes the Tula Iontophoresis System (IPS) with TYMBION™ otic anesthetic for local anesthesia of the ea... Read More
Gender:
ALL
Ages:
Between 6 months and 17 years
Trial Updated:
07/19/2024
Locations: Columbia University Vagelos College of Physicians and Surgeons, New York, New York
Conditions: Otitis Media With Effusion, Acute Otitis Media, Otitis Media