New York is currently home to 4475 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
The Tetherâ„¢ - Vertebral Body Tethering System Post Approval Study
Recruiting
This study is an opportunity to provide continued reasonable assurance of the safety and probable benefit of The Tether HUD. The study will collect long term safety and efficacy information from patients who have had their idiopathic scoliosis treated via anterior vertebral body tethering (AVBT) with The Tether.
Gender:
ALL
Ages:
All
Trial Updated:
02/21/2024
Locations: Mount Sinai, New York, New York
Conditions: Scoliosis Idiopathic
Comparing Hypothermic Temperatures During Hemiarch Surgery
Recruiting
Hypothermic circulatory arrest is an important surgical technique, allowing complex aortic surgeries to be performed safely. Hypothermic circulatory arrest provides protection to cerebral and visceral organs, but may result in longer cardiopulmonary bypass times during surgery, increased risks of bleeding, inflammation, and neuronal injury. To manage these consequences, a trend towards warmer core body temperatures during circulatory arrest has emerged. This trial will randomize patients to eith... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/21/2024
Locations: Mount Sinai Hospital, New York, New York
Conditions: Thoracic Aortic Disease
A Study of hSTC810 in Combination With Paclitaxel in Relapsed or Refractory Extensive Stage Small Cell Lung Cancer
Recruiting
The purpose of this clinical study is to assess the safety and efficacy of hSTC810 and paclitaxel combination therapy in patients with relapsed or refractory extensive stage small cell lung cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/20/2024
Locations: Tisch Cancer Institute at Mount Sinai, New York, New York
Conditions: Extensive Stage Small Cell Lung Cancer
Evaluation of OLX10212 in Patients With Neovascular Age-related Macular Degeneration
Recruiting
This is a Phase 1, multicenter, open-label, single- and multi-dose, dose-escalating study of OLX10212 in patients with neovascular age-related macular degeneration (AMD). This study is composed of 2 parts: Part A and Part B. Part A is a single ascending dose study, and Part B is a multiple ascending dose study. The primary objective is to evaluate the safety and tolerability of single and multiple intravitreal injection(s) of OLX10212 in patients with neovascular AMD. The exploratory objectives... Read More
Gender:
ALL
Ages:
50 years and above
Trial Updated:
02/20/2024
Locations: Ophthalmic Consultants of the Capital Region, Troy, New York
Conditions: Neovascular Age-related Macular Degeneration
Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease
Recruiting
COMPLETE-2 is a prospective, multi-centre, randomized controlled trial comparing a strategy of physiology-guided complete revascularization to angiography-guided complete revascularization in patients with acute ST-segment elevation myocardial infarction (STEMI) or non-ST-segment elevation myocardial infarction (NSTEMI) and multivessel coronary artery disease (CAD) who have undergone successful culprit lesion Percutaneous Coronary Intervention (PCI). COMPLETE-2 OCT is a large scale, prospective... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/14/2024
Locations: Bassett Medical Center, Cooperstown, New York
Conditions: Acute Myocardial Infarction, Coronary Artery Disease
An Open Label, Randomized Study of Neoadjuvant Nivolumab and Chemotherapy, With or Without Sub-ablative Stereotactic Body Radiation Therapy, for Resectable Stage IIA to IIIB Non-small Cell Lung Cancer
Recruiting
An open label, randomized study of neoadjuvant nivolumab and chemotherapy, with or without sub-ablative stereotactic body radiation therapy, for resectable stage IIA to IIIB non-small cell lung cancer
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/13/2024
Locations: Montefiore Medical Center-Albert Einstein College of Medicine, Bronx, New York
Conditions: Resectable Stage IIA to IIIB Non-small Cell Lung Cancer
Trial of Belimumab in Early Lupus
Recruiting
This two year study will evaluate the effects of giving belimumab (Benlysta) to patients with Early Lupus. Early lupus is a diagnosis of lupus within 2 years. Subjects will be randomized to receive belimumab or placebo during the first year. During the second year, subjects who were randomized to belimumab will be rerandomized to continue to receive belimumab or to receive placebo. The study will look at clinical effects as well as effects on the immune system.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/13/2024
Locations: Feinstein Institute, Manhasset, New York
Conditions: Lupus Erythematosus, Systemic, Lupus Erythematosus
Longitudinal Study of Urea Cycle Disorders
Recruiting
Urea cycle disorders (UCD) are a group of rare inherited metabolism disorders. Infants and children with UCD commonly experience episodes of vomiting, lethargy, and coma. The purpose of this study is to perform a long-term analysis of a large group of individuals with various UCDs. The study will focus on the natural history, disease progression, treatment, and outcome of individuals with UCD.
Gender:
ALL
Ages:
All
Trial Updated:
02/10/2024
Locations: Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: Brain Diseases, Metabolic, Inborn, Amino Acid Metabolism, Inborn Errors, Urea Cycle Disorders
Strength and Muscle Related Outcomes for Nutrition and Lung Function in CF
Recruiting
The goal of the study is to examine multiple markers of anthropometrics, body composition, sarcopenia and frailty and compare them to dual energy X-ray absorptiometry (DXA) output, which is considered the current clinical gold-standard tool to measure body composition. The result of this study will provide detailed data regarding the nutrition and body composition within this Cystic Fibrosis population and also provide a baseline evaluation for use of these biomarkers in the future studies inclu... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/09/2024
Locations: New York Medical College (NYMC), Hawthorne, New York
Conditions: Cystic Fibrosis
Comparison of Intraocular Pressure Measurement With the Novel TonoVera Device With Other Commonly Used Devices
Recruiting
We are testing the accuracy of Reichert's Tono-Vera tonometer by comparing measurements of IOP with this device and measurements with other commonly-used tonometers, including Goldmann Applanation and iCare.
Gender:
ALL
Ages:
All
Trial Updated:
02/08/2024
Locations: Ross Eye Institute, Buffalo, New York
Conditions: Glaucoma
Pedometer Coaching to Promote Postoperative Ambulation
Recruiting
The goal of this randomized controlled trial is to evaluate whether remote pedometer follow-up and virtual coaching can improve ambulation after major abdominopelvic surgery, and how this affects key postoperative outcomes. The main questions it aims to answer are: * Does pedometer-guided ambulation coaching increases ambulation after surgery? * Does pedometer-guided coaching improve satisfaction, quality of recovery, while reducing postoperative complications? Participants will be asked to i... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/06/2024
Locations: Stony Brook University Hospital, Stony Brook, New York
Conditions: Postoperative Outcomes
Vagus Nerve Stimulator for Autism and Other Developmental Disorders
Recruiting
The goal of this flexible single-subject design vagus nerve stimulation (VNS) study is to examine the behavioral, cognitive, and biorhythmic effects of VNS in children and adults with autism and developmental disabilities. The main aims are: * Pilot the creation of a profile for those who will respond to VNS with the long-term goal of designing clinical trials. * Examine the effects of VNS on a broad range of symptoms. Participants will select between 1, 2, or 3 months of daily VNS treatment a... Read More
Gender:
ALL
Ages:
Between 12 years and 40 years
Trial Updated:
02/06/2024
Locations: New York State Psychiatric Institute, New York, New York
Conditions: Autism Spectrum Disorder, Intellectual Disability, Autonomic Nervous System, Developmental Disability