New York is currently home to 4475 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Enteral Anastomosis for the Treatment of Gastric Outlet Obstruction: A Randomized Controlled Study Comparing Endoscopic Versus Surgical Gastrojejunostomy
Recruiting
Gastric outlet obstruction (GOO) occurs commonly in malignancies involving the periampullary region (cancers originating in the head of the pancreas, duodenum, bile duct, or ampulla) or the distal stomach. GOO not only causes debilitating symptoms such as nausea, vomiting, inability to tolerate oral intake, and prevents adequate nutritional intake. Therefore, providing therapy for GOO is imperative to improve the quality of life, and nutritional status of these patients, as well as allow them to... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/06/2024
Locations: North Shore University Hospital, Manhasset, New York
Conditions: Gastric Outlet Obstruction
Trisol System EFS Study
Recruiting
The objective of this early feasibility study is to gain early clinical insight into Trisol system safety and performance to treat patients with moderate or greater tricuspid regurgitation (TR).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/06/2024
Locations: Columbia University Medical Center/NYPH, New York, New York
Conditions: Tricuspid Regurgitation
Orphan Europe Carbaglu® Surveillance Protocol
Recruiting
The purpose of this study is to conduct post-marketing surveillance of carglumic acid (Carbaglu) to obtain long-term clinical safety information. Carglumic acid was approved by the United States Food and Drug Administration (FDA) for treatment of acute hyperammonemia due to N-acetylglutamate synthase (NAGS) deficiency. Much of the FDA-required data is already collected through the Longitudinal Study of Urea Cycle Disorders (RDCRN Protocol #5101). This study will collect additional data on advers... Read More
Gender:
ALL
Ages:
All
Trial Updated:
02/06/2024
Locations: Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: N-acetylglutamate Synthase (NAGS) Deficiency
Use of Ritual Epost Postnatal Multivitamins During the Postpartum Period
Recruiting
Multivitamin/multimineral supplements (MVI) provide important nutrition supplement to the diet of pregnant women to cover potential deficiencies and optimize nutrition status of both mom and baby, especially when the diet is suboptimal or nutrient demand is high while absorption is hindered by various factors such as genetic variance and gastrointestinal function. It is, however, largely unknown whether using an MVI during the lactating period helps improve nutrition status of mom and baby. In t... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
02/05/2024
Locations: Brooklyn College of City University of New York, Brooklyn, New York
Conditions: Lactation Disorder - Postpartum Condition or Complication, Nutrition, Healthy
Use of Ritual Prenatal Multivitamins for Pregnancy
Recruiting
Prenatal multivitamin/multimineral supplements (MVI) provide important nutrition supplement to the diet of pregnant women to cover potential deficiencies and optimize nutrition status of both mom and baby, especially when the diet is suboptimal or nutrient demand is high while absorption is hindered by various factors such as genetic variance and gastrointestinal function. In this double-blind, randomized, controlled trial, the investigators will recruit 70 pregnant women at gestational week 12-... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
02/05/2024
Locations: Brooklyn College of City University of New York, Brooklyn, New York
Conditions: Pregnancy Related, Nutrition, Healthy
Focal US-guided Cryo-ablation Using DynaCAD / UroNAV Preplanning / Guidance of Intermediate Risk Prostate Cancer
Recruiting
The purpose of this research study is to determine the safety and feasibility of using the UroNav software and DynaCAD software for planning and treating prostate cancer as an add on to the already approved workflow of using ultrasound only during the cryoablation of the prostate. The software application may aid doctors in locating a prior biopsy proven cancer location from the UroNav biopsy that patients previously had and then use that information to guide the treatment.
Gender:
MALE
Ages:
45 years and above
Trial Updated:
02/01/2024
Locations: The Smith Institute for Urology, Lake Success, New York
Conditions: Prostate Cancer, Prostate Disease
MR/TRUS Fusion Guided Prostate Biopsy - An Improved Way to Detect and Quantify Prostate Cancer
Recruiting
This research study is designed to determine if targeted Magnetic Resonance Imaging (MRI) Ultrasound (US) fusion biopsy is better than the standard of care ultrasound guided biopsy alone in diagnosing subjects with clinically significant prostate cancer with MRI visible lesions. This study will consist of comparing the standard of care (ultrasound guided prostate biopsy) with the protocol biopsy which consists of an ultrasound guided prostate biopsy and a MRI/US fusion tracked prostate biopsy.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
02/01/2024
Locations: The Smith Institute for Urology, Lake Success, New York
Conditions: Prostate Disease, Elevated Prostate Specific Antigen, Family History of Prostate Cancer, Positive Digital Rectal Exam, Prostate Cancer
Safety, Tolerability and Pharmacokinetics of a Monoclonal Antibody Specific to B-and T-Lymphocyte Attenuator (BTLA) as Monotherapy and in Combination With an Anti-PD1 Monoclonal Antibody for Injection in Subjects With Advanced Malignancies
Recruiting
The primary objective is to assess the safety and tolerability of TAB004 as monotherapy and in combination with toripalimab in subjects with selected advanced solid malignancies, including lymphoma, and to evaluate the recommended Phase 2 dose. The secondary objectives are to: 1) describe the pharmacokinetic (PK) profile of TAB004 monotherapy and in combination with toripalimab and to describe the PK profile of toripalimab when administered with TAB004, 2) evaluate antitumor activity of TAB004... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/01/2024
Locations: Northwell Health, New Hyde Park, New York
Conditions: Advanced Unresectable Solid Tumor, Metastatic Solid Tumor
Identifai Genetics Analytic Validity Study - Compound Heterozygosity and Samples Collection
Recruiting
The purpose of this study is to validate a noninvasive prenatal diagnosis procedure for genetic conditions in the developing fetus by analyzing fetal genetic material present in the pregnant mother's blood.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
01/31/2024
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Prenatal Diagnosis, Genetics
The Acute Burn ResUscitation Multicenter Prospective Trial
Recruiting
This is a prospective randomized multi-center study which will compare acute fluid resuscitation using a colloid strategy (LR + 5% Albumin) to a crystalloid strategy (LR alone), in adults with an acute burn involving at least 25% of their total body surface area.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/31/2024
Locations: Erie County Medical Center, Buffalo, New York
Conditions: Burn Injury
Study Evaluating Safety and Efficacy of UCART123v1.2 in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Recruiting
Phase I, open-label, dose-escalation and dose-expansion study evaluating the safety and efficacy of Universal Chimeric Antigen Receptor T-cell (UCART) targeting the Cluster of Differentiation 123 (CD123) in patients with relapsed/refractory acute myeloid leukemia (AML). The purpose of this study is to evaluate the safety and clinical activity of Universal Chimeric Antigen Receptor T-cells targeting CD123 (UCART123v1.2) and determine the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/31/2024
Locations: Roswell Park Cancer Institute, Buffalo, New York
Conditions: Relapsed/Refractory Acute Myeloid Leukemia
Socialization To Enrich Participation & Support Sexuality for Young People With I/DD
Recruiting
The goal of this clinical trial is to test the effectiveness of a 6-week socialization and sex education curriculum (STEPS2) in young people (aged 16-27 years) with intellectual and developmental disabilities (I/DD), including people with Down syndrome. The main question it aims to answer is: Does the STEPS2 health education curriculum increase the proportion of individuals who: 1. have had a discussion with a medical professional about their sexual health (including sexually transmitted infe... Read More
Gender:
ALL
Ages:
Between 16 years and 27 years
Trial Updated:
01/29/2024
Locations: CUNY School of Public Health (but interventions are virtual), New York, New York
Conditions: Knowledge, Behavior