New York is currently home to 4507 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Defibrotide Dose-escalation for SOS Post-HSCT
Recruiting
This research study is being done to determine the safety and tolerability of increasing doses of defibrotide within a single patient with sinusoidal obstructive syndrome (SOS)/veno-occlusive disease (VOD) after hematopoietic cell transplantation (HCT) associated with either kidney and/or lung impairment that has not obtained a complete response (CR) or progressed in severity with standard doses of defibrotide.
Gender:
ALL
Ages:
Between 1 month and 75 years
Trial Updated:
03/22/2024
Locations: New York Medical College, Valhalla, New York
Conditions: Sinusoidal Obstruction Syndrome, Veno-occlusive Disease
Neo-adjuvant Treatment for Squamous Cell Carcinoma Using Direct Tumor Injection With RP1.
Recruiting
This is a Phase 1b, single-center, open-label study, evaluating efficacy and safety of RP1 for the treatment of resectable cutaneous Squamous Cell Carcinoma in up to 12 evaluable patients. In this study, patients will receive RP1 via direct intratumoral (IT) injection into superficial cutaneous solid tumors to assess the safety and tolerability as well efficacy of RP1 treatment. The primary efficacy population is up to 12 evaluable patients with resectable CSCC. The enrollment of patients with C... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/22/2024
Locations: Rochester Dermatologic Surgery, Victor, New York
Conditions: Squamous Cell Carcinoma, RP1
The Effects of Music Therapy on Adult Patients Requiring Mechanical Ventilation in the ICU
Recruiting
While most studies in the medical literature that indicate "music" as an intervention may recognize its impact and capacity to decrease pain perception, anxiety, and/or its role in the regulation of cardiac and respiratory function in ICU patients, no identifiable studies have implemented entrained live music therapy protocols into clinical trials. Music therapy treatment is a non-pharmacological intervention that is individually tailored to the patient's needs and focuses on the assessment and... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/22/2024
Locations: Mount Sinai West, New York, New York
Conditions: Acute Respiratory Distress Syndrome, Acute Hypoxemic Respiratory Failure, Acute Hypercapnic Respiratory Failure
Concurrent Chemotherapy Plus HFR Radiation Therapy in Inoperable NSCLC
Recruiting
The standard treatment for patients with Non-Small Cell Lung Cancer (NSCLC) and clinically negative lymph nodes remains surgery per current guidelines. Five year survival for patients with stage I non-small cell lung cancer is generally greater than 50% after surgery. Many of these patients have heart and lung issues or other diseases which keep them from undergoing curative surgery. Studies have shown that majority of these patients die from their cancer and not from their other diseases. This... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/22/2024
Locations: SUNY Upstate Medical University, Syracuse, New York
Conditions: Non-small Cell Lung Cancer
Establish the Role of Premotor and Motor Cortices in tDCS-facilitated Speech Motor Learning
Recruiting
Groups of unimpaired participants will all receive speech motor training of nonwords, and six tDCS conditions will be compared: anodal tDCS over speech motor regions; cathodal tDCS over speech motor regions; anodal tDCS over left frontal regions; cathodal tDCS over left frontal regions; cathodal stimulation over non-speech motor regions (anodal already collected);and sham tDCS (no stimulation). This will address a basic science question about whether the mechanism underlying speech motor learnin... Read More
Gender:
ALL
Ages:
Between 18 years and 35 years
Trial Updated:
03/21/2024
Locations: New York University Department of Communicative Sciences and Disorders, New York, New York
Conditions: Healthy
Assessing Dynamic Reading Behaviors Using Eye-Tracking Tobii Glasses
Recruiting
HYPOTHESIS: 1. Horizontal convergence tracked with Tobii glasses is a reliable substitute for accommodation in young myopes and hyperopes with normal accommodative amplitudes 2. Young mypopes and hyperopes demonstrate different reading behaviors during near work AIMS \& OBJECTIVES: 1. Compare the accommodative responses measured with the Grand Seiko open-field autorefractor to those derived from the Tobii Glasses, when subjects wear (1) spectacle glasses, (2) single vision contact lenses (SVC... Read More
Gender:
ALL
Ages:
Between 18 years and 30 years
Trial Updated:
03/21/2024
Locations: Xiaoying Zhu, New York, New York
Conditions: Accommodation
Systems Aligning for Equity (SAFE) Spaces
Recruiting
The goal of this 2-arm cluster randomized clinical trial is to test whether an evidence-based staff training and coaching model specifically designed as a response to legal system-involved youths' and frontline staff's mental health needs can improve the safety and suicide outcomes, mental health challenges, and wellness and facility climate for youth and staff in facilities assigned to the intervention condition. Staff in facilities assigned to the intervention are eligible to receive evidence-... Read More
Gender:
ALL
Ages:
All
Trial Updated:
03/21/2024
Locations: New York University, New York, New York
Conditions: Suicide, Mental Disorder, Mental Health, Burnout, Professional, Self Harm
Treatment With Romosozumab to Improve Bone Mineral Density and Architecture in Chronic SCI
Recruiting
The objective of the proposed work is to determine whether administration for 12 months of romosozumab (evenity) followed by 12 months of denosumab (prolia) will maintain bone mass at the knee in subjects with chronic SCI.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/21/2024
Locations: James J. Peters VA Medical Center, Bronx, New York
Conditions: Osteoporosis, Spinal Cord Injuries
Evaluating the Effects of Tasimelteon in Individuals With Autism Spectrum Disorder (ASD) and Sleep Disturbances
Recruiting
This is a multicenter, open-label study to evaluate the efficacy and safety of a daily single oral dose of tasimelteon in treating sleep disturbances in pediatric and adult participants with ASD.
Gender:
ALL
Ages:
Between 2 years and 65 years
Trial Updated:
03/19/2024
Locations: Vanda Investigational Site, Staten Island, New York
Conditions: Autism Spectrum Disorder, Sleep Disorder, Neurological Disorder, Sleep Disturbance
A Study of BTX-A51 in People With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome
Recruiting
This is an open-label, dose escalation study to evaluate the safety, toxicity, and pharmacokinetics (PK) as well as preliminary efficacy of BTX-A51 capsules in participants with relapsed or refractory acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS). The study will be done in three parts. Part 1a (Monotherapy Dose Escalation) of this study is designed to determine the dose-limiting toxicities (DLTs) and maximum tolerated dose (MTD) of orally administered BTX-A51 in up to... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/19/2024
Locations: Memorial Sloan-Kettering Cancer Center, New York, New York
Conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome
Identification and Treatment Of Micrometastatic Disease in Stage III Colon Cancer
Recruiting
This research study is comparing two standard of care treatment options based on blood test results for participants who have metastatic colon cancer. The names of the potential treatments involved in this study are: * Active surveillance * FOLFIRI treatment * Nivolumab treatment * Encorafenib/Binimetinib/Cetuximab treatment * Trastuzumab + Pertuzumab
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/19/2024
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Metastatic Colon Cancer, Stage III Colon Cancer
Metastatic Tumor Research and Outcomes Network
Recruiting
The registry aims to collect patient information such as patient demographics, co-morbidities, clinical, diagnostic, and therapeutic data, as well as information on adverse events and HRQOL outcomes specific for patients with metastatic spine tumor(s).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/19/2024
Locations: Memorial Sloan-Kettering Cancer Center, New York, New York
Conditions: Metastatic Spine Tumor