New York is currently home to 4476 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Neuroimaging and CBD for Opiod Use Disorder
Recruiting
The investigators propose an imaging study to investigate the neurobiological effects of CBD (vs placebo) in participants with opioid use disorder who are maintained on methadone. The purpose of the study is to determine the neural circuits and transmitters associated with the effects of CBD on to reduce craving and anxiety. The neuroimaging will be conducted in participants immediately following their first administration of CBD (800mg or placebo) and one week after the last administration (3 d... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
09/25/2023
Locations: Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: Heroin Abuse, Opioid Use Disorder, Substance-Related Disorders, Opioid-Related Disorders
Artificial Intelligence (AI) Enabled, Cloud-based ECG Diagnostic Solution (ZBPro) Feasibility Testing
Recruiting
The proposed research is to address the accessibility and affordability of technology to capture symptomatic and asymptomatic cardiac events via Long-Term Continuous Electrocardiogram Monitoring (LTCM), and to provide physicians with full access to their patients' recorded data in a timely manner. We adopt an FDA cleared single- lead OEM patch Holter made of flexible material to make long-term wearing more comfortable and more patient compliant. The patch transmits the recorded data to our cloud... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/23/2023
Locations: Stony Brook University, Stony Brook, New York
Conditions: Arrhythmias, Cardiac
OPN-375 Efficacy and Safety in Adolescents With Bilateral Nasal Polyps
Recruiting
This is a 16-Week Randomized, Double-Blind, Placebo Controlled, Parallel-Group, Multicenter Study Evaluating the Efficacy and Safety of OPN-375 186 μg Twice a Day (BID) in Adolescents with Bilateral Nasal Polyps followed by a 12-Week Open-Label Treatment Phase. The total planned number of subjects is approximately 120 adolescents (12-17 years of age) who will be randomly assigned to receive 1 of 2 study treatments using a 2:1 ratio (OPN-375 186 μg: Placebo). For the PK sub-study, up to 14 subjec... Read More
Gender:
ALL
Ages:
Between 12 years and 17 years
Trial Updated:
09/22/2023
Locations: University of Rochester, Rochester, New York
Conditions: Bilateral Nasal Polyposis
Whole Genome Sequencing (WGS) on IVF Embryos and Individual Patients
Recruiting
This research project aims to utilise recent advances in whole genome sequencing of preimplantation genetic diagnosis embryos to investigate the impact of paternal age on de novo mutation rates in IVF embryos. Embryos that are deemed unsuitable for transfer following preimplantation genetic testing for monogenic/single gene disorders (PGT-M) due to the detection of genetic abnormalities will be utilized for this study. These embryos will undergo re-biopsy, and both the biopsied samples as well a... Read More
Gender:
ALL
Ages:
Between 18 years and 48 years
Trial Updated:
09/21/2023
Locations: Neway Fertility, New York, New York
Conditions: Fertility Issues, Single-Gene Defects
Trial of Maintenance With Niraparib- Uterine Serous Carcinoma
Recruiting
Uterine serous carcinoma (USC) accounts for up to 40% of endometrial cancer-related deaths. Patients with USC share many genomic and clinical characteristics with patients who has serous ovarian cancer. The objective of this study is to evaluate the efficacy of maintenance Niraparib regimen in patients with advanced or platinum sensitive recurrent uterine serous carcinoma. Additionally, the investigators aim to further describe the safety of this regimen. The investigators hypothesize that Nirap... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
09/20/2023
Locations: Imbert Cancer Center Northwell Health, Bay Shore, New York
Conditions: Endometrial Cancer, Papillary Serous Endometrial Carcinoma, Uterine Serous Carcinoma, Endometrial Carcinoma, Cancer of the Endometrium
PA4Health Physical Activity App Open Pilot Study for African American Women
Recruiting
Test the acceptability of a smartphone physical activity app for African American women
Gender:
FEMALE
Ages:
Between 18 years and 64 years
Trial Updated:
09/18/2023
Locations: City University of New York School of Public Health & Health Policy, New York, New York
Conditions: Test Acceptability/Usability of a Physical Activity App Developed for African American Women
The Effect of Electronic Cigarette Use on Smoking Behaviors Among Smokers Receiving Outpatient Psychiatric Treatment
Recruiting
This study aims to establish the feasibility and acceptability of a project designed to investigate the impact of electronic cigarette use on combustible cigarette smoking and smoking-related factors among smokers with psychiatric disorders, a high-risk population, who are not yet ready to quit smoking. All participants will be instructed to switch completely from combustible cigarettes to e-cigarettes for the next 8 weeks. They will be assessed at baseline, 2 weeks, 4 weeks, 8 weeks and 12 week... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
09/15/2023
Locations: Montefiore Behavioral Health Center, Bronx, New York
Conditions: Tobacco Smoking, Psychiatric Disorders
Diagnostic Knee Needle Arthroscopy in Predicting Unicompartmental Knee Osteoarthritis
Recruiting
Plain radiographs and MRI play an important role in the diagnosis of intra-articular knee pathology and can be used to guide treatment decisions. These imaging modalities however have several limitations which can lead to misdiagnosis, incorrect treatment decisions, and suboptimal patient care. The gold standard for confirmation of intra-articular knee pathology is formal diagnostic knee arthroscopy. Diagnostic knee arthroscopy must be performed in the operating room under general anesthesia, wh... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
09/14/2023
Locations: Albany Medical Center, Albany, New York
Conditions: Arthroplasty, Replacement, Knee
Impact of Cerebellar TMS on Brain and Cognitive Functions in Schizophrenia: a Pilot Study
Recruiting
This is a single-site, sham-controlled, randomized trial in a total of 60 subjects between ages 18 and 40 years with schizophrenia. This study will investigate the effects of 4-week rTMS treatment on brain and cognitive functions in patients. Subjects will be randomized to one of the following arms: Arm 1: Standard of Care (SOC) and active rTMS Arm 2: Standard of Care (SOC) and sham rTMS Each participant will receive rTMS five days per week, for four consecutive weeks. Functional magnetic reso... Read More
Gender:
ALL
Ages:
Between 18 years and 40 years
Trial Updated:
09/12/2023
Locations: Zucker Hillside Hospital, New York, New York
Conditions: Schizophrenia, Cerebellar Function, Condition
Clinical Nurse Specialist Led Early Palliative Survivorship Care for Patients With Advanced Cancer
Recruiting
The purpose of the randomized control trial is to estimate the effect of an oncology clinical nurse specialist-led early intervention multidisciplinary approach to palliative and survivorship care within two previously identified and validated patient groups having metastatic solid tumor malignancy on patient-reported symptom burden, patient-reported overall quality of life (QOL), distress, and overall survival. The primary hypothesis is that the effect of an oncology clinical nurse specialist-... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
09/11/2023
Locations: Good Samaritan University Hospital, West Islip, New York
Conditions: Solid Tumor, Adult, Metastasis
The Effects of Respiratory Training on Voice
Recruiting
Primary muscle tension dysphonia is a voice disorder that involves excessive and poorly coordinated muscle activity affecting multiple subsystems that are involved in speech production, in the absence of structural or neurologic abnormalities of the larynx. Primary muscle tension dysphonia (MTD) is one of the most common forms of voice disorders, accounting for at least 40% of patients seen in voice clinics. Perceptually the voice sounds hoarse and strained, with reduced loudness and pitch range... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/09/2023
Locations: Syracuse University, Syracuse, New York
Conditions: Muscle Tension Dysphonia
Non-Invasive Quantification of Liver Health in NASH (N-QUAN)
Recruiting
To evaluate, in patients with suspected NASH referred for liver biopsy, the diagnostic performance of CT1 at discriminating those with NAS≥4 \& F≥2 from those without.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
09/07/2023
Locations: Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: NASH - Nonalcoholic Steatohepatitis