New York is currently home to 4473 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Extended-release Tablets in Pediatric Subjects Aged 5 to 17 Years With Active, Mild to Moderate Ulcerative Colitis
Recruiting
This is a randomized, double-blind, placebo-controlled, multicenter, study to evaluate the efficacy, safety, and pharmacokinetics (PK) of budesonide extended-release tablets for the induction of remission in pediatric subjects, with active, mild to moderate ulcerative colitis (UC). Subjects will be permitted to continue taking background oral or rectal 5-aminosalicylate (5-ASA) products.
Gender:
ALL
Ages:
Between 5 years and 17 years
Trial Updated:
10/05/2023
Locations: Bausch Health Site 006, Bronx, New York
Conditions: Ulcerative Colitis
CAN-Stim Compared to SNS in Treatment of Urinary Urgency Incontinence With Wireless Neuromodulation Technology
Recruiting
This is a prospective, randomized, controlled, multi-center, study in which 150 evaluable subjects will be randomized 1:1 to receive either a Protect CAN-Stim or SNS InterStim® system. Subjects from both groups will immediately start with therapy. The primary endpoint is a ≥ 50% reduction in number of incontinence episodes associated with urgency at the 3-month visit, with additional measurements assessed at 14 days, 1, 6, 9 and 12-months.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/03/2023
Locations: Urology - Iris Cantor Men's Health Center, New York, New York
Conditions: Urinary Incontinence, Urge
Triple-masking v Double-masking: a Trial of Scientific Publication in Public Health
Recruiting
The trial is designed to determine whether knowledge of the identity of the authors, their institutions and of the reviewers of a given article submitted to American Journal of Public Health impacts the final editorial decision. The concept of triple masked editorial process (where editors are unaware of author identities and affiliations in addition to the authors' and reviewers' identities being masked from one another) compared to a double masked process (only authors' and reviewers' identiti... Read More
Gender:
ALL
Ages:
All
Trial Updated:
10/02/2023
Locations: QueensC, New York, New York
Conditions: Publication of Articles Submitted to the American Journal of Public Health
Imaging of T-cell Activation With [18F]F-AraG in Advanced Non Small Cell Lung Cancer
Recruiting
This is a pilot study using \[18F\]F AraG PET imaging to evaluate the immunological response to checkpoint inhibitor therapy (CkIT) in patients with advanced NSCLC tumors at multiple study sites. The main objectives of the study are to quantify the change in \[18F\]F AraG PET signal before and after CkIT therapy, and to correlate this change in \[18F\]F AraG PET signal with a radiographic response.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/27/2023
Locations: Stony Brook University, Stony Brook, New York
Conditions: Non Small Cell Lung Cancer
Post-Approval Study of the TREO Abdominal Stent-Graft System
Recruiting
The purpose of this study is to determine the long-term performance of the TREO Abdominal Stent-Graft as a treatment for patients with Infrarenal Abdominal Aortic Aneurysms or Aorto-iliac Aneurysms.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/27/2023
Locations: Montefiore Medical Center, Bronx, New York
Conditions: Abdominal Aortic Aneurysm
ImPACT Normative Extension
Recruiting
The researchers want to find out more about a standalone software application, ImPACT Online and how it relates to other commonly used tests of memory, attention and reaction time. ImPACT Online is a computer-based neurocognitive test for concussion management. The test was designed to help measure the effects of concussion on cognitive processes (for example, memory, attention, brain speed) and visual functioning.
Gender:
ALL
Ages:
Between 60 years and 80 years
Trial Updated:
09/27/2023
Locations: University of Albany, Albany, New York
Conditions: Brain Concussion
Accuracy of Doppler Ultrasound Versus Manual Palpation of Pulse in Cardiac Arrest
Recruiting
The FloPatch FP120 device is indicated for use for the noninvasive assessment of blood flow in the carotid artery. The FloPatch FP120 device uses ultrasound and the Doppler effect to non-invasively assess the flow of flood. In this study, the FloPatch FP120 will be applied to the neck at the location of the carotid artery on cardiac arrest patients in the emergency department. FloPatch FP120 data will be compared with arterial line blood pressure to assess for accuracy of pulse checks among card... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/26/2023
Locations: North Shore University Hospital, Manhasset, New York
Conditions: Cardiac Arrest
Operant Conditioning of the Soleus Stretch Reflex in Adults With Cerebral Palsy
Recruiting
12 adults with spastic CP will complete 6 baseline sessions and 24 down conditioning sessions held 3 times/week. All clinical and physiological assessments collected at baseline will be reassessed after study completion, and follow ups after 2 weeks, 1 month and 3 months. The soleus H reflex (electric analogue of the stretch reflex) will be elicited in all sessions. In each session, participants will complete 20 baseline trials and 225 down conditioning trials to decrease the magnitude of the H-... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/25/2023
Locations: Burke Neurological Institute, White Plains, New York
Conditions: Cerebral Palsy, Spastic Cerebral Palsy
Multi-site Study for Evaluation of Clinical Ranges of Whole Blood Clotting Times of Patients on Anticoagulants and Verification of Measurement Precision of Liquid Quality Controls With the Perosphere Technologies' PoC Coagulometer
Recruiting
The Perosphere Technologies' PoC Coagulometer measures clotting times of fresh whole blood samples. Clotting is initiated by glass surface activation and terminates on optical detection of fibrin assembly, the final step in the coagulation cascade. Since activation occurs at the top of the intrinsic pathway and detection occurs at the bottom of the final common pathway, the Perosphere Technologies' PoC Coagulometer has shown sensitivity to a broad range of drugs and reagents that affect blood cl... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
09/25/2023
Locations: Perosphere Technologies Inc., White Plains, New York
Conditions: Coagulation
Neuroimaging and CBD for Opiod Use Disorder
Recruiting
The investigators propose an imaging study to investigate the neurobiological effects of CBD (vs placebo) in participants with opioid use disorder who are maintained on methadone. The purpose of the study is to determine the neural circuits and transmitters associated with the effects of CBD on to reduce craving and anxiety. The neuroimaging will be conducted in participants immediately following their first administration of CBD (800mg or placebo) and one week after the last administration (3 d... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
09/25/2023
Locations: Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: Heroin Abuse, Opioid Use Disorder, Substance-Related Disorders, Opioid-Related Disorders
Artificial Intelligence (AI) Enabled, Cloud-based ECG Diagnostic Solution (ZBPro) Feasibility Testing
Recruiting
The proposed research is to address the accessibility and affordability of technology to capture symptomatic and asymptomatic cardiac events via Long-Term Continuous Electrocardiogram Monitoring (LTCM), and to provide physicians with full access to their patients' recorded data in a timely manner. We adopt an FDA cleared single- lead OEM patch Holter made of flexible material to make long-term wearing more comfortable and more patient compliant. The patch transmits the recorded data to our cloud... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/23/2023
Locations: Stony Brook University, Stony Brook, New York
Conditions: Arrhythmias, Cardiac
OPN-375 Efficacy and Safety in Adolescents With Bilateral Nasal Polyps
Recruiting
This is a 16-Week Randomized, Double-Blind, Placebo Controlled, Parallel-Group, Multicenter Study Evaluating the Efficacy and Safety of OPN-375 186 μg Twice a Day (BID) in Adolescents with Bilateral Nasal Polyps followed by a 12-Week Open-Label Treatment Phase. The total planned number of subjects is approximately 120 adolescents (12-17 years of age) who will be randomly assigned to receive 1 of 2 study treatments using a 2:1 ratio (OPN-375 186 μg: Placebo). For the PK sub-study, up to 14 subjec... Read More
Gender:
ALL
Ages:
Between 12 years and 17 years
Trial Updated:
09/22/2023
Locations: University of Rochester, Rochester, New York
Conditions: Bilateral Nasal Polyposis