New York is currently home to 4602 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Using MOST to Optimize an Intervention to Increase COVID-19 Testing for Frontline Essential Workers
Recruiting
COVID-19 testing is essential to controlling the COVID-19 pandemic to break transmission chains and reduce community transmission. However, Black and Latino/Hispanic populations in lower status frontline essential occupations such as food preparation, retail, building maintenance, personal services, and in-home health care have serious barriers to COVID-19 testing and, therefore, insufficient testing rates. The proposed study will use the multiphase optimization strategy framework to address the... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
05/12/2023
Locations: New York University Silver School of Social Work, New York, New York
Conditions: COVID-19, COVID-19 Testing
ROSE-Longitudinal Assessment With Neuroimaging
Recruiting
The investigators will perform follow-up on 250 of 500 cases recruited into the ROSE study of cases with deep and lobar intracerebral hemorrhage to perform advanced neuroimaging at 12-24 months post stroke, and evaluations of motor and cognitive function at baseline, 6 months after baseline, and 12 months after baseline to determine predictors of recovery, progressive cognitive or functional impairment. The investigators propose to leverage the recruitment, DNA, RNA-seq and baseline advanced neu... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/11/2023
Locations: Columbia University, New York, New York
Conditions: Intracerebral Hemorrhage
Tislelizumab Consolidation After Liver-Directed Therapy for Hepatocellular Carcinoma
Recruiting
The investigators hypothesize that the addition of Tislelizumab after definitive local therapy for locally advanced inoperable Hepatocellular carcinoma (HCC) will synergize with local therapy as well as treat micro metastatic disease and improve one year progression-free survival rates for participants and optimize local control.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/10/2023
Locations: Montefiore Medical Center, Bronx, New York
Conditions: Carcinoma, Hepatocellular, Liver Cell Carcinoma
COVID-19 Outcome Prediction Algorithm
Recruiting
Severe acute respiratory syndrome coronavirus 2-mediated coronavirus disease (COVID-19) is an evolutionarily unprecedented natural experiment that causes major changes to the host immune system. We propose to develop a test that accurately predicts short- and long-term (within one-year) outcomes in hospitalized COVID-19 patients broadly reflecting US demographics who are at increased risk of adverse outcomes from COVID-19 using both clinical and molecular data. We will enroll patients from a hos... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/09/2023
Locations: Bronx VA Medical Center, Bronx, New York
Conditions: COVID-19, Post Acute Sequelae of COVID-19, Long COVID, Organ Dysfunction Syndrome, Multiple, Frailty Syndrome
Mobility Opportunities Via Education/Experience (MOVE): Healthcare Impact Assessment
Recruiting
The purpose of this study is to determine whether participation in the Mobility Opportunities Via Education (MOVE) program is associated with reduced use of healthcare for individuals with developmental disabilities.
Gender:
All
Ages:
Between 5 years and 65 years
Trial Updated:
05/08/2023
Locations: Center for Disability Services, Albany, New York
Conditions: Quality of Life, Health Care Utilization
Eye Movement Rehabilitation in Low Vision Patients
Recruiting
Approximately 217 million people worldwide currently suffer from low vision, which impacts a broad range of activities of daily living and is associated with depression and increased mortality. Over half of the patients presenting for low vision services have eye disease that affects the fovea and surrounding macula and leads to central vision loss (CVL). People with CVL are forced to use eccentric vision as a substitute for their impaired fovea, however eye movement control and visual function... Read More
Gender:
All
Ages:
Between 14 years and 99 years
Trial Updated:
05/02/2023
Locations: Lighthouse Guild, New York, New York
Conditions: Low Vision, Age Related Macular Degeneration
BS01 in Patients With Retinitis Pigmentosa
Recruiting
Non-randomized, open label, Phase 1/2 dose escalation study of BS01, a non-replicating, rep/cap-deleted, recombinant adeno-associated virus vector expressing an enhanced light-sensitive channelrhodopsin gene (ChronosFP).
Gender:
All
Ages:
18 years and above
Trial Updated:
05/01/2023
Locations: OCLI, New York, New York
Conditions: Retinitis Pigmentosa
Evaluation of Closed Incision Negative Pressure Dressing (PREVENA) to Prevent Lower Extremity Amputation Wound Complications
Recruiting
This study is a prospective, multi-center, two-arm, unblinded, and randomized controlled trial with a goal of evaluating the impact of a closed incision negative pressure dressing (PREVENA) on incidence of post-operative wound complications and medical costs in patients undergoing lower extremity amputation.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/01/2023
Locations: Westchester Medical Center, Valhalla, New York
Conditions: Amputation, Amputation; Postoperative, Sequelae, Wound Dehiscence, Seroma, Wound Infection, Surgical, Lymph Leakage
Reducing Self-Stigma Among Individuals With History of Childhood Maltreatment
Recruiting
Individuals who report experiencing any kind of abuse during childhood report shame and self-blame, often leading to self-stigma and a reluctance to reveal their experiences and seek help. Such stigma may aggravate the mental health consequences of child maltreatment (CM). The aim of the proposed study is twofold: (1) to evaluate the effectiveness of a brief video-based intervention in reducing self-stigma among individuals who experienced childhood abuse and/or maltreatment, and (2) to increas... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
04/26/2023
Locations: New York State Psychiatric Institute, New York, New York
Conditions: Stigma, Social, Child Abuse, Child Neglect, Help-Seeking Behavior
KRT-232 Versus Best Available Therapy for the Treatment of Subjects With Myelofibrosis Who Are Relapsed or Refractory to JAK Inhibitor Treatment
Recruiting
This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2, for the treatment of patients with myelofibrosis (MF) who no longer benefit from treatment with a JAK inhibitor. Inhibition of MDM2 is a novel mechanism of action in MF. This study will be conducted in 2 phases. Phase 2 will determine the KRT-232 recommended dose and dosing schedule; Phase 3 will test KRT-232 vs Best Available Therapy (BAT). Patients in the Phase 3 part of the study will be randomized 2:1 to receive ei... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/26/2023
Locations: Brookdale University Hospital and Medical Center, Brooklyn, New York
Conditions: Primary Myelofibrosis (PMF), Post-Polycythemia Vera MF (Post-PV-MF), Post-Essential Thrombocythemia MF (Post-ET-MF)
MIT-001 for Prevention of CCRT-Induced OM in HNSCC Patients
Recruiting
The proposed study in patients with previously untreated locally advanced head and neck squamous cell carcinoma (HNSCC) is designed to evaluate the efficacy and safety of three different doses of MIT-001 compared to the placebo in prevention of oral mucositis (OM) in patients with HNSCC who are undergoing concurrent chemoradiotherapy (CCRT).
Gender:
All
Ages:
18 years and above
Trial Updated:
04/21/2023
Locations: James P. Wilmot Cancer Center, Rochester, New York
Conditions: Oral Mucositis, Head and Neck Squamous Cell Carcinoma
HIIT Effects on Cardiometabolic Health
Recruiting
The primary aim of this randomized clinical trial is to compare the effects of three different HIIT protocols and a control group on cardiometabolic health in young adults with obesity. Participants will be randomly assigned to one of the following three groups, with each having varying work-to-rest ratios: 1) HIIT-A, 2) HIIT-B, 3) HIIT-C, and 4) control group. HIIT-A, HIIT-B, and HIIT-C groups will participate in six sessions of a running based HIIT program over a 2-week training period. Pre-cl... Read More
Gender:
All
Ages:
Between 18 years and 25 years
Trial Updated:
04/19/2023
Locations: Women's Building, Syracuse, New York
Conditions: Obesity, Cardiovascular Diseases, Metabolic Disease, High-intensity Interval Training