New York is currently home to 4476 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including New York, Rochester, Bronx and Buffalo. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Study of Voruciclib Alone or in Combination With Venetoclax in Subjects With B-Cell Malignancies or AML
Recruiting
This is a Phase 1, open-label, dose escalation study to determine the safety and preliminary efficacy of voruciclib monotherapy in subjects with relapsed/refractory B cell malignancies or AML after failure of standard therapies or voruciclib in combination with venetoclax in subjects with relapsed or refractory AML
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/03/2023
Locations: New York University, New York, New York
Conditions: Follicular Lymphoma (FL), Mantle Cell Lymphoma (MCL), Marginal Zone Lymphoma (MZL), Small Lymphocytic Lymphoma (SLL), Chronic Lymphocytic Leukemia (CLL), Diffuse Large B-cell Lymphoma (DLBCL), Acute Myeloid Leukemia (AML)
Venetoclax and Lintuzumab-Ac225 in AML Patients
Recruiting
The study is a multicenter, open label Phase I/II trial. 1. To determine the maximum tolerated dose (MTD) of lintuzumab-Ac225 added to venetoclax for patients with CD33 positive relapsed/refractory AML. (Phase 1 portion) 2. To assess the percentage of patients with CR, CRh, or Overall Response (CR + CRh), up to 6 months after the start of treatment without receiving other AML therapies. (Phase 2 portion)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/02/2023
Locations: Weill Cornell Medicine, New York, New York
Conditions: Acute Myeloid Leukemia, Relapsed Adult AML
CT for Personalized Mechanical Ventilation
Recruiting
The goal of this study is to compare two different ways of helping patients with a condition called sepsis who need help breathing using a machine called a ventilator. The investigators want to study which way of setting the ventilator is better for the lungs. Here are the main questions the investigators want to answer: 1. How does the amount of air in the lungs and the way it moves differ between the two ways? 2. How does the way air spreads out in different parts of the lungs differ between... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/28/2023
Locations: Columbia University, New York, New York
Conditions: Ventilator-Induced Lung Injury, Sepsis Syndrome, Mechanical Ventilation Complication
Groningen International Study on Sentinel Nodes in Vulvar Cancer-III
Recruiting
Vulvar cancer patients with SN-metastasis \> 2mm will receive chemoradiation instead of an inguinofemoral lymphadenectomy.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/27/2023
Locations: Memorial Sloan Kettering Commack, Commack, New York
Conditions: Vulvar Cancer, Sentinel Lymph Node, Lymph Node Metastases
Total Shoulder Arthroplasty Multi-Center Registry
Recruiting
The objective of the study is a multi-center prospective registry to collect clinical outcomes of anatomic and reverse total shoulder arthroplasty.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
07/27/2023
Locations: The Rothman Institute, New York, New York
Conditions: Shoulder Arthroplasty
A Novel Virtual Reality Task in Parkinson's Disease
Recruiting
The purpose of this study is to compare experiences and effects of a virtual reality physical program to an in-person Rock Steady Boxing Program. People with Parkinson's disease, age 18 and up, who participate in Rock Steady Boxing weekly may join this study.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/24/2023
Locations: NYIT, Old Westbury, New York
Conditions: Parkinson Disease
Simple Bone Cysts in Kids
Recruiting
Simple bone cysts (SBCs) are cysts filled with fluid that occur most frequently in the long bones (arms or legs) of children. There are many ways to treat SBCs but it is unclear if one is better than another. The purpose of this research trial is to compare the effectiveness of two common treatments that are used by surgeons today.
Gender:
ALL
Ages:
Between 2 years and 21 years
Trial Updated:
07/10/2023
Locations: The Children's Hospital at Montefiore, Bronx, New York
Conditions: Bone Cyst
Injury Prevention Model For K-1 Students
Recruiting
There is no educational injury prevention model uniquely suited for kindergarten and first grade (K-1) students. The Teddy Bear Injury Clinic (TBIC) is a unique modification of the teddy bear clinic to facilitate classroom injury prevention teaching The TBIC will be administered to K-1 students, aged 5-7 years. Initial analysis will be descriptive and qualitative. Subsequent randomization of students to test and control groups followed by statistical analysis will be done to evaluate for effect... Read More
Gender:
ALL
Ages:
Between 5 years and 7 years
Trial Updated:
07/06/2023
Locations: Good Samaritan Hospital, West Islip, New York
Conditions: Trauma Injury, Child Behavior
Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working
Recruiting
This phase II/III trial compares the effect of the combination of olaparib and temozolomide to the usual treatment (trabectedin and pazopanib) for uterine leiomyosarcoma that has spread to other places in the body (advanced) after initial chemotherapy has stopped working. Olaparib is a PARP inhibitor. PARP is a protein that helps repair damaged deoxyribonucleic acid (DNA). Blocking PARP may prevent tumor cells from repairing their damaged DNA, causing them to die. PARP inhibitors are a type of t... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/05/2023
Locations: Columbia University/Herbert Irving Cancer Center, New York, New York
Conditions: Locally Advanced Leiomyosarcoma, Metastatic Leiomyosarcoma, Stage III Uterine Corpus Leiomyosarcoma AJCC v8, Stage IV Uterine Corpus Leiomyosarcoma AJCC v8, Unresectable Leiomyosarcoma, Uterine Corpus Leiomyosarcoma
Diabetic Foot Ulcers-Comparing Transforming Powder to Standard of Care
Recruiting
Phase IV, randomized, prospective, multi-center, open-label, comparison of transforming powder dressing to standard of care dressing for healing diabetic foot ulcers.
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
06/27/2023
Locations: Bronx Foot Care, Bronx, New York
Conditions: Diabetic Foot Ulcer
Chemoreflex and Baroreflex Alterations Causing Postural Tachycardia Syndrome With Orthostatic Hyperpnea and Hypocapnia
Recruiting
Postural tachycardia syndrome (POTS) is the most common chronic cause of postural lightheadedness, and upright confusion afflicting many Americans, mostly young women. Many POTS patients hyperventilate by increasing their depth of breathing that produces tachycardia, alters blood flow and blood pooling in the body and importantly reduces brain blood flow causing "brain fog". In this proposal the investigators will demonstrate in young women that abnormal repeated brief impairment of blood pressu... Read More
Gender:
FEMALE
Ages:
Between 15 years and 39 years
Trial Updated:
06/20/2023
Locations: NewYork Medical College, Hawthorne, New York
Conditions: Postural Orthostatic Tachycardia Syndrome, Hypocapnia, Hyperventilation
TRIAD Appendicitis Decision-making Surveys
Recruiting
While appendectomy has been the main treatment of appendicitis for over 100 years, recent European studies found that, at least among highly selected patients, antibiotics alone can be an effective alternative. Surgeons and patients alike have a difficult time deciding if surgery or antibiotics are the best choice to treat appendicitis. The goal of the TRIAD is to evaluate the patients who are a part of the TRIAD implementation program and assess satisfaction and decisional regret for patients w... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/13/2023
Locations: Columbia University Medical Center, New York, New York
Conditions: Appendicitis