Wisconsin is currently home to 1328 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Milwaukee, Madison, Green Bay and Marshfield. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Artisan Aphakia Lens for the Correction of Aphakia in Children
Recruiting
The purpose of this study is to determine the safety and effectiveness of the Artisan Aphakia Lens in the treatment of aphakia in children.
Gender:
All
Ages:
Between 2 years and 21 years
Trial Updated:
06/24/2022
Locations: UW-Madison, Madison, Wisconsin
Conditions: Aphakia
Artisan Aphakia Lens for the Correction of Aphakia (Secondary) in Adults
Recruiting
This study will determine the safety and effectiveness of the Artisan Aphakia Lens when used as a secondary implant to correct aphakia in adults.
Gender:
All
Ages:
22 years and above
Trial Updated:
06/24/2022
Locations: Valley Eye Associates, Appleton, Wisconsin
Conditions: Aphakia
Tabelecleucel for Solid Organ or Allogeneic Hematopoietic Cell Transplant Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease (EBV+ PTLD) After Failure of Rituximab or Rituximab and Chemotherapy
Recruiting
The purpose of this study is to determine the clinical benefit and characterize the safety profile of tabelecleucel for the treatment of Epstein-Barr virus-associated post-transplant lymphoproliferative disease (EBV+ PTLD) in the setting of (1) solid organ transplant (SOT) after failure of rituximab and rituximab plus chemotherapy or (2) allogeneic hematopoietic cell transplant (HCT) after failure of rituximab.
Gender:
All
Ages:
All
Trial Updated:
06/23/2022
Locations: Froedtert Hospital & the Medical College of Wisconsin (Adults only), Milwaukee, Wisconsin
Conditions: Epstein-Barr Virus+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD), Solid Organ Transplant Complications, Lymphoproliferative Disorders, Allogeneic Hematopoietic Cell Transplant, Stem Cell Transplant Complications
Non-Guided vs. Guided Surgery to Immediately Loaded PrimeTaper Implants in Partially Edentulous Patients
Recruiting
A 510k approved dental device for subjects requiring single or multiple tooth replacement with implants where immediate restoration/loading is preferred.
Gender:
All
Ages:
25 years and above
Trial Updated:
05/25/2022
Locations: WisNova Institute of Dental Specialists, Kenosha, Wisconsin
Conditions: Partially Edentulous Maxilla or Mandible
Renal Metabolism in Salt-sensitive Human Blood Pressure
Recruiting
Salt sensitive hypertension is a significant health problem worldwide and a primary modifiable risk factor for renal, cardiovascular, and cerebrovascular diseases. Yet, the underlying mechanisms remain poorly understood. The proposed study determines how renal oxygenation and substrate metabolism differs between individuals with and without salt sensitivity, with the ultimate goal of identifying mechanisms, diagnostic criteria, and treatment strategies for salt sensitive hypertension.
Gender:
All
Ages:
Between 30 years and 65 years
Trial Updated:
05/23/2022
Locations: Medical College of Wisconsin /Froedtert Hospital, Milwaukee, Wisconsin
Conditions: Hypertension
Engaging Patients in Mutual Goal-Setting in Hospitalized Patients
Recruiting
Mutual goal setting and action planning in patients with long-term conditions in outpatient settings is associated with favorable effects on measures of physical health, psychological health, subjective health status, self-management self-efficacy levels, activation levels, and perceived empowerment. The purpose of this study is to examine the impact of an educational intervention delivered to the staff nurses of two surgical units on how to engage patients in mutual goal-setting in the acute ca... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/19/2022
Locations: Froedtert Memorial Hospital, Milwaukee, Wisconsin
Conditions: Goals
Dipraglurant (ADX48621) for the Treatment of Patients With Parkinson's Disease Receiving Levodopa-based Therapy
Recruiting
This study is designed to evaluate the safety and efficacy of dipraglurant in PD patients with dyskinesia (randomized 1:1 to receive active or placebo) for 12 weeks (1 week at 150 mg per day and 11 weeks at 300 mg per day). The primary efficacy assessment will be based on the Unified Dyskinesia Rating Scale (UDysRS). Patients who complete the 12-week blinded treatment period may have the option to roll into an open-label safety extension study for an additional 12-month treatment period.
Gender:
All
Ages:
Between 30 years and 85 years
Trial Updated:
05/18/2022
Locations: University of Wisconsin Hospitals and Clinics, Madison, Wisconsin
Conditions: Parkinson Disease, Dyskinesia, Drug-Induced, Dyskinesias
EMST and Swallowing in Long-Term Survivors of HNCA
Recruiting
This study is a randomized trial examining the impact of expiratory muscle strength training (EMST) on oral intake, swallowing function, and swallow-related quality of life in persons treated for cancer of the head and neck (HNCA) with radiation therapy or chemoradiotherapy (RT/CRT) at least 5 years previously.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/16/2022
Locations: University of Wisconsin Milwaukee, Milwaukee, Wisconsin
Conditions: Head and Neck Neoplasms, Deglutition Disorders
Study of ISB 1342, a CD38/CD3 Bispecific Antibody, in Subjects With Previously Treated Multiple Myeloma
Recruiting
The purpose of this study is to assess safety, efficacy, pharmacokinetic (PK)/pharmacodynamic (PD), and immunogenicity with ISB 1342 in subjects with relapsed/refractory multiple myeloma.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/10/2022
Locations: University of Wisconsin Hospital and Clinics, Madison, Wisconsin
Conditions: Relapsed/Refractory Multiple Myeloma
Peri-neural Electrical Dry Needling Migraine Treatment Study
Recruiting
This study seeks to determine the effectiveness of a specific treatment protocol using dry needling with perineural electrical stimulation in comparison to standard treatment in physical therapy for patients with migraine headaches. This will be a randomized cross-over study in which participants will be in the first arm of the study, have a washout period, then cross over to the other arm of the study.
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
05/06/2022
Locations: Ascension Rehabilitation Services, Milwaukee, Wisconsin
Conditions: Migraine Headache
Study of the Effects of Fabrazyme Treatment on Lactation and Infants
Recruiting
The study will last for up to 2 years (24 months). Full participation for both mother and infant is 24 months, full participation of mother and development of infant is 24 months, while full participation of mother and no infant participation is 6 months
Gender:
All
Ages:
All
Trial Updated:
05/04/2022
Locations: investigational site number 01Rhead, Milwaukee, Wisconsin
Conditions: Fabry Disease, Alpha Galactosidase A Deficiency
A Study to Evaluate the Efficacy and Safety of Rosnilimab (ANB030) in Treatment of Subjects With Moderate-to-Severe Alopecia Areata
Recruiting
Efficacy and safety of rosnilimab (ANB030) in subjects with moderate-to-severe Alopecia Areata
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/03/2022
Locations: Site 10-114, Kenosha, Wisconsin
Conditions: Alopecia Areata