Wisconsin is currently home to 1348 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Milwaukee, Madison, Green Bay and Marshfield. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer
NCT05361174
Recruiting
This is a study to investigate the efficacy and safety of an infusion of IOV-4001 in adult participants with unresectable or metastatic melanoma or advanced non-small-cell lung cancer (NSCLC).
Gender:
All
Ages:
18 years and above
Trial Updated:
08/21/2023
Locations: Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Unresectable Melanoma, Metastatic Melanoma, Stage III Non-small Cell Lung Cancer, Stage IV Non-small Cell Lung Cancer
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Fractionated CO2 Laser With and Without Clobetasol for Treatment of Vulvar Lichen Sclerosus
NCT04951206
Recruiting
This is a randomized placebo-controlled trial design to determine whether combining FxCO2-laser with the traditional therapy of clobetasol propionate 0.05% ointment (combined treatment) as compared to FxCO2-laser and placebo ointment (FxCO2-laser only) will improve treatment response in women undergoing FxCO2-laser for vulvar lichen sclerosus. Primary objective: To evaluate if women with LS who undergo FxCO2 laser therapy and concomitant TCS (clobetasol group) have higher treatment success (def... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
08/21/2023
Locations: Waukesha Memorial Hospital, Waukesha, Wisconsin
Conditions: Vulvar Lichen Sclerosus
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Effects of Transcranial Direct Current Stimulation (tDCS) on Language
NCT04166513
Recruiting
This study will investigate the effects of mild electrical stimulation in conjunction with speech therapy for people with post-stroke aphasia to enhance language recovery.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
08/18/2023
Locations: Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Stroke, Aphasia
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Study of TSR-042, an Anti-programmed Cell Death-1 Receptor (PD-1) Monoclonal Antibody, in Participants With Advanced Solid Tumors
NCT02715284
Recruiting
This is a multi-center, open-label, first-in-human Phase 1 study evaluating the anti-programmed death receptor 1 (anti-PD-1) antibody dostarlimab (also known as TSR-042) n participants with advanced solid tumors who have limited available treatment options. The study will be conducted in 2 parts with Part 1 consisting of safety evaluation, pharmacokinetics (PK), and pharmacodynamics (PDy) of escalating doses of dostarlimab. Dose escalation will be based on ascending weight-based dose levels (DLs... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/18/2023
Locations: GSK Investigational Site, Milwaukee, Wisconsin
Conditions: Neoplasms
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Screening Protocol for Tumor Antigen Expression Profiling and HLA Typing for Eligibility Determination
NCT02636855
Recruiting
This screening study is intended for men and women ≥ 18 to ≤ 75 years of age who have advanced solid or hematologic malignancy. The study will assess a subject's human leukocyte antigen (HLA) subtype and tumor antigen expression profile. Based on the results, it will be determined if a subject is eligible to be considered for Adaptimmune sponsored clinical trials testing the safety and efficacy of genetically changed T cells targeting specific tumor antigens. No treatment intervention will occur... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/18/2023
Locations: Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Solid and Hematological Malignancies
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A Study Evaluating the Efficacy and Safety of IV L-Citrulline for the Prevention of Clinical Sequelae of Acute Lung Injury Induced by Cardiopulmonary Bypass in Pediatric Patients Undergoing Surgery for Congenital Heart Defects
NCT05253209
Recruiting
This is a randomized, double-blind, placebo controlled, multicenter study to compare the efficacy and safety of L-citrulline versus placebo in patients undergoing surgery for congenital heart defects. Eligible patients undergoing repair of a large unrestrictive ventricular septal defect (VSD), a partial or complete atrioventricular septal defect (AVSD), or an ostium primum atrial septal defect (primum ASD) will be eligible for enrollment.
Gender:
All
Ages:
18 years and below
Trial Updated:
08/17/2023
Locations: University of Wisconsin-Madison, Madison, Wisconsin
Conditions: Ventricular Septal Defect, Atrioventricular Septal Defect, Primum Atrial Septal Defect
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Pancreatic Cancer Adaptive Neoadjuvant Chemotherapy Trial
NCT03322995
Recruiting
This is an open-label, phase II study in patients with resectable and borderline resectable pancreas cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/17/2023
Locations: Froedtert & the Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Pancreatic Cancer
Register for Updates
Evaluation of an Online Comprehensive Behavioral Intervention for Tics (CBIT) Therapist Training Program
NCT05547854
Recruiting
Tic disorders are a class of childhood-onset neuropsychiatric disorders that occur in 1-3% of the population. Studies have shown that a non-drug treatment known as Comprehensive Behavioral Intervention for Tics (CBIT) is more effective than supportive therapy for reducing tics in children and adults. Although CBIT is now recommended as a first-line intervention for tic disorders, many patients do not have access to CBIT, in part due to a lack of trained therapists. Currently, the only option ava... Read More
Gender:
All
Ages:
7 years and above
Trial Updated:
08/16/2023
Locations: Marquette University, Milwaukee, Wisconsin
Conditions: Tics, Tic Disorders, Tourette Syndrome
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Diagnosis of Fatty Liver With Outpatient Ultrasound
NCT03542578
Recruiting
This study will evaluate whether ultrasound performed during outpatient visit is effective in early diagnosis of fatty liver.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
08/14/2023
Locations: Froedtert Hospital, Milwaukee, Wisconsin
Conditions: Liver Steatoses
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Determining the Effectiveness of earLy Intensive Versus Escalation Approaches for RRMS
NCT03535298
Recruiting
The DELIVER-MS study seeks to answer the question: Does early treatment with highly effective DMT improve the prognosis for people with MS? This is an area of significant controversy and no data currently exist to guide treatment choices for patients and clinicians. The study results will help guide overall treatment philosophy and will be applicable not only to a wide range of existing therapies but also to new therapies, meeting a significant unmet need in patient decision making and aiding th... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
08/14/2023
Locations: University of Wisconsin-Madison, Madison, Wisconsin
Conditions: Multiple Sclerosis, Relapsing-Remitting
Register for Updates
Cerebral Oxygen Saturation and Cytochrome Oxidase REDOX State in Children With Epilepsy: A Pilot Study
NCT03054961
Recruiting
The purpose of this pilot study is to describe the relationship of regional cerebral oximetry and cytoximetry, measured using near-infrared spectroscopy, with seizure activity in the periictal period in children with epilepsy.
Gender:
All
Ages:
18 years and below
Trial Updated:
08/14/2023
Locations: The Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Epilepsies, Partial
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Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors
NCT05040360
Recruiting
This phase II trial studies the effect of capecitabine and temozolomide after surgery in treating patients with high-risk well-differentiated pancreatic neuroendocrine tumors. Chemotherapy drugs, such as capecitabine and temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving capecitabine and temozolomide after surgery could prevent or delay the return of cancer in patients wit... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/11/2023
Locations: Duluth Clinic Ashland, Ashland, Wisconsin
Conditions: Metastatic Malignant Neoplasm in the Liver, Pancreatic Neuroendocrine Tumor, Stage I Pancreatic Neuroendocrine Tumor AJCC v8, Stage II Pancreatic Neuroendocrine Tumor AJCC v8, Stage III Pancreatic Neuroendocrine Tumor AJCC v8
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