Florida is currently home to 3759 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Study of GalaFLEX LITE™ Scaffold in Treatment of Capsular Contracture After Breast Implant Augmentation
Recruiting
Prospective, randomized, controlled study to assess the safety and effectiveness of GalaFLEX LITE™ Scaffold in revision surgery for reduction of capsular contracture recurrence and/or malposition in implant-based breast augmentation patients versus patients undergoing conventional revision surgery with no supportive matrix or acellular dermal matrix (ADM). Subjects will be randomized 2:1 to receive either GalaFLEX LITE™ Scaffold or standard care (no ADM or matrix placement). This study is design... Read More
Gender:
FEMALE
Ages:
Between 22 years and 66 years
Trial Updated:
03/17/2025
Locations: Billington Plastic Surgery, Saint Petersburg, Florida
Conditions: Capsular Contracture Associated With Breast Implant, Capsular Contracture Grade III, Capsular Contracture Grade IV
ORCHID: An Online Intervention for Persons With HIV (Miami)
Recruiting
The purpose of this research is to test ORCHID (Optimizing Resilience \& Coping with HIV through Internet Delivery), a skills-building intervention that improves mental health status for persons with HIV, who are at-risk for falling out of care.
Gender:
FEMALE
Ages:
Between 18 years and 90 years
Trial Updated:
03/17/2025
Locations: University of Miami School of Medicine, Miami, Florida
Conditions: HIV/AIDS, HPV Infection
Lupus Landmark Study: A Prospective Registry and Biorepository
Recruiting
The purpose of the registry and biorepository is to provide a mechanism to store clinical data, linked biospecimens and molecular data to support the conduct of future research on Systemic Lupus Erythematosus (SLE), including Lupus Nephritis (LN).
Gender:
ALL
Ages:
Between 18 years and 110 years
Trial Updated:
03/17/2025
Locations: University of Miami, Miami, Florida
Conditions: Systemic Lupus Erythematosus (SLE), Lupus Nephritis, Neuropsychiatric Systemic Lupus Erythematosus
Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging
Recruiting
CAPTIVA-MRI is an observational multimodal MR imaging study that is ancillary to the CAPTIVA trial \[a 3-arm, double-blind Phase III trial conducted at approximately 115 StrokeNet sites randomizing patients with stroke attributed to 70-99% intracranial atherosclerotic stenosis (ICAS) to aspirin plus ticagrelor, clopidogrel, or rivaroxaban.\] The primary goal of this ancillary study is to determine if MRI biomarkers can potentially identify ICAS patients who fail best medical management. The CAPT... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/17/2025
Locations: Baptist Medical Center Jacksonville, Jacksonville, Florida
Conditions: Stroke, Intracranial Atherosclerotic Stenosis (ICAS)
A Clinical Study to Assess the Efficacy and Safety of Leriglitazone in Adult Male Subjects With Cerebral Adrenoleukodystrophy
Recruiting
A Clinical Study to Assess the Efficacy and Safety of Leriglitazone in Adults Male Subjects with Cerebral Adrenoleukodystrophy.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
03/17/2025
Locations: Neuro Medicine Hospital / UF Health, Gainesville, Florida
Conditions: Cerebral Adrenoleukodystrophy (cALD)
Phase I Study to Assess the Safety and Efficacy of OCU200 for Center-Involved Diabetic Macular Edema (DME)
Recruiting
A Phase 1 study to assess the safety and efficacy of OCU200 for center-involved diabetic macular edema
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/17/2025
Locations: Advanced Research LLC, Deerfield Beach, Florida
Conditions: Center Involved Diabetic Macular Edema, Diabetic Macular Edema
Study Testing Benefits of Ursolic Acid (UA) as a Countermeasure To Myopenia and Insulin Resistance in Chronic Spinal Cord Injury (SCI)
Recruiting
This study will evaluate if Ursolic Acid supplementation may be effective in reducing muscle loss and improving blood sugar control in the SCI community.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
03/17/2025
Locations: University of Miami - Miami Project to Cure Paralysis, Miami, Florida
Conditions: Spinal Cord Injuries, Tetraplegia, Paraplegia, Muscle Loss, Atrophy, Muscular, Insulin Resistance
Comparison of EVAR and ESAR for Infrarenal Aortic Aneurysms With a Wide Proximal Neck
Recruiting
The HERCULES trial is a Randomized controlled clinical trial designed to prospectively compare endosuture aneurysm repair (ESAR) to standard endovascular aneurysm repair (EVAR) clinical outcomes in treatment of infrarenal abdominal aortic aneurysm (AAA) in subjects having wide proximal aortic neck diameters (≥ 28mm and ≤ 32mm).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/17/2025
Locations: Mt Sinai Med Ctr, Miami Beach, Florida
Conditions: Aortic Aneurysm, Abdominal
Study of ORIC-944 in Patients with Metastatic Prostate Cancer
Recruiting
The purpose of this study is to establish the safety and preliminary antitumor activity of ORIC-944 as a single agent and in combinations with ARPIs in patients with metastatic prostate cancer.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
03/17/2025
Locations: South Florida Oncology and Hematology, Plantation, Florida
Conditions: Metastatic Prostate Cancer
A Long-Term Safety Study of PTC923 in Participants With Phenylketonuria
Recruiting
The main purpose of this study is to evaluate the long-term safety of PTC923 in participants with phenylketonuria, and to evaluate the changes from baseline in dietary phenylalanine (Phe)/protein consumption.
Gender:
ALL
Ages:
All
Trial Updated:
03/17/2025
Locations: UF College of Medicine, Department of Pediatrics Division of Genetics and Metabolism, Gainesville, Florida
Conditions: Phenylketonuria
A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2
Recruiting
This study is being done to see if a drug called disitamab vedotin, alone or with pembrolizumab, works to treat HER2 expressing urothelial cancer. It will also test how safe the drug is for participants. Participants will have cancer that has spread in the body near where it started (locally advanced) and cannot be removed (unresectable) or has spread through the body (metastatic). It will also study what side effects happen when participants get the drug. A side effect is anything a drug does... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/17/2025
Locations: Florida Cancer Specialists - South Region, Fort Myers, Florida
Conditions: Urothelial Carcinoma
A Study to Evaluate the Safety, Efficacy, PK, PD and Immunogenicity of Cipaglucosidase Alfa/Miglustat in IOPD Subjects Aged 0 to <18
Recruiting
This is a Phase 3, open-label, multicenter study to evaluate the safety, efficacy, PK, PD, and immunogenicity of cipaglucosidase alfa/miglustat treatment in ERT-experienced and ERT-naïve pediatric subjects with IOPD.
Gender:
ALL
Ages:
17 years and below
Trial Updated:
03/17/2025
Locations: University of Florida Clinical Research Center, Gainesville, Florida
Conditions: Glycogen Storage Disease Type II Infantile Onset