Florida is currently home to 3787 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
First in Human Study in Subjects With Obesity, But Otherwise Healthy
Recruiting
This is a First in Human study to evaluate the safety and tolerability of DA-1726 following single and multiple doses in participants with obesity, but otherwise healthy subjects.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
05/20/2025
Locations: Clinical Pharmacology of Miami, LLC, Miami, Florida
Conditions: Obesity
Identification and Differentiation of Thyroid Nodules by Acoustic Imaging and Viscoelastic Parameters
Recruiting
This study is being done to identify and differentiate thyroid nodules by acoustic imaging and viscoelastic parameters.
Gender:
ALL
Ages:
8 years and above
Trial Updated:
05/20/2025
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Thyroid Gland Carcinoma
A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer
Recruiting
The main purpose of the master is to help the research sites and sponsor carry out several clinical trials more efficiently by providing a common research protocol. Individual clinical trials under this master protocol define drug/disease-specific research goals and activities to test them. New studies will be added as new drugs emerge against different cancers. Participation in the trial will depend on how long the benefit lasts.
Gender:
ALL
Ages:
Between 1 year and 39 years
Trial Updated:
05/20/2025
Locations: Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida
Conditions: Neoplasms, Child, Adolescent
A Study of GC012F (AZD0120), a CAR T Therapy Targeting CD19 and BCMA in Subjects With Relapsed/Refractory Multiple Myeloma
Recruiting
This trial is a phase 1b/2, open-label, multicenter study of GC012F (AZD0120), a CD19/BCMA dual CART-cell therapy, in adult subjects with relapsed/refractory Multiple Myeloma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/20/2025
Locations: Research Site, Jacksonville, Florida
Conditions: Relapsed/ Refractory Multiple Myeloma
An Adaptive Phase 2a/2b Study of LY3871801 in Adult Participants With Rheumatoid Arthritis
Recruiting
The main purpose of this study is to evaluate the efficacy and safety of LY3871801 in adult participants with active moderately-to-severe rheumatoid arthritis (RA).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/20/2025
Locations: Integrity Clinical Research, Doral, Florida
Conditions: Rheumatoid Arthritis
Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer
Recruiting
This phase III trial compares the effect of sentinel lymph node mapping to standard lymph node dissection in reducing the risk of swelling in the legs (lymphedema) in patients undergoing a hysterectomy for stage I endometrial cancer. Standard lymph node dissection removes lymph nodes around the uterus during a hysterectomy to look for spread of cancer from the uterus to nearby lymph nodes. Sentinel lymph node mapping uses a special dye and camera to look for cancer that may have spread to nearby... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/20/2025
Locations: UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables, Florida
Conditions: Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8
A Prospective and Retrospective Observational Study of Multidrug-Resistant Patient Outcomes With and Without Ibalizumab
Recruiting
The virological efficacy of ibalizumab has been clearly demonstrated in multiple clinical trials. This study will expand ibalizumab's clinical data set and allow a better understanding of the virologic response durability on ARV regimens with or without ibalizumab in a heterogeneous real-world patient population. Additional data on the efficacy and safety of ibalizumab and its impact on patient reported outcomes will be captured until study end. Primary Objective: To evaluate the long-term eff... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/20/2025
Locations: Aids Healthcare Foundation, Fort Lauderdale, Florida
Conditions: HIV Infections, Multi-Antiviral Resistance
Infusion of Autologous T Cells Engineered to Target FSH Receptor in Recurrent Ovarian Cancer
Recruiting
The purpose of this first in human study is to evaluate the safety of treatment with autologous T cells genetically modified to express a CER (chimeric endocrine receptor) targeting the FSHR (follicle-stimulating hormone receptor) (FSHCER T cells), with or without conditioning chemotherapy, in participants with recurrent or persistent ovarian, fallopian tube, or primary peritoneal cancer.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/20/2025
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Ovarian Cancer
A Study of Baricitinib (LY3009104) in Children With COVID-19
Recruiting
The purpose for this study is to determine if the study drug baricitinib is effective and safe in hospitalized pediatric participants with Coronavirus disease 2019 (COVID -19) and to confirm the dose.
Gender:
ALL
Ages:
Between 2 years and 18 years
Trial Updated:
05/20/2025
Locations: Arnold Palmer Hospital for Children, Orlando, Florida
Conditions: Covid19, Corona Virus Infection
Vyxeos Plus Gilteritinib in Relapsed or Refractory, FLT3-Mutated AML
Recruiting
This study combines vyxeos and gilteritinib in patients with relapsed or refractory FLT3-mutated acute myeloid leukemia. Vyxeos and gilteritinib will be given as induction therapy. Those patients entering a complete remission or a complete remission with incomplete blood count recovery will be allowed to proceed to consolidation therapy with vyxeos and gilteritinib. Those patients who do not proceed to an allogeneic stem cell transplant for any reason are able to enter the maintenance phase of t... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/20/2025
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Acute Myeloid Leukemia With FLT3/ITD Mutation
Lung Ultrasound Artefact Analysis for Exclusion of Acute Rejection in Lung Transplant Recipients
Recruiting
This study is being done to study a safe and non-invasive way to diagnose lung rejection and infection.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/20/2025
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Post-Lung Transplantation Bronchiectasis
DASH INtervention to INvestigate the Gut
Recruiting
The study investigators will recruit a generally healthy sample of 112 black and white adults from Birmingham, AL to participate in a 28-day randomized, controlled feeding study. Participants will be randomized to receive either the DASH diet or a standard American diet. All meals will be provided by the study. Fecal samples will be collected at multiple time points before, during, and after the dietary intervention and will be analyzed using PCR to amplify the V4 region of the 16S rRNA gene and... Read More
Gender:
ALL
Ages:
Between 19 years and 65 years
Trial Updated:
05/20/2025
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Microbiota, Cancer