Florida is currently home to 3835 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Adaptive Therapy of Vismodegib in Advanced Basal Cell Carcinoma
Recruiting
The purpose of this study is to compare how well tolerated and effective four different dosing schedules (two personalized, intermittent dosing schedules as compared to a fixed intermittent and continuous dosing regimen) work in people with advanced basal cell carcinoma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/16/2025
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Advanced Basal Cell Carcinoma
Effects of CBD/CBD-A Oral Extract on Resting-state EEG and Neuropathic Pain Symptoms After SCI
Recruiting
The main purposes of this study are to (1) measure the effect of CBD/CBD-A on pain symptoms, pain intensity, pain unpleasantness, and skin sensitivity to hot and cold temperatures; and (2) measure the effect of CBD on brain electrical activity with electroencephalography (EEG).
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
06/16/2025
Locations: Lynn Rehabilitation Center, Miami, Florida
Conditions: SCI - Spinal Cord Injury, Neuropathic Pain
International Multicentric Observational Study to Characterize Subpopulations of Patients With Autism Spectrum Disorder
Recruiting
To determine sufficient number of biological and clinical markers to identify subgroups of potential best responders to a specific medication
Gender:
ALL
Ages:
Between 12 years and 65 years
Trial Updated:
06/16/2025
Locations: The Angel Medical Research, Miami Lakes, Florida
Conditions: Autism Spectrum Disorder
Safety and Efficacy of Oral Belumosudil in Black or African American, American Indian or Alaska Native, and Native Hawaiian or Other Pacific Islander Male and Female Participants Aged 12 Years and Above With Chronic Graft Versus Host Disease (cGVHD) After At Least 2 Prior Lines of Systemic Therapy
Recruiting
The purpose of this study is to measure safety and efficacy of oral belumosudil in Black or African American, American Indian or Alaska Native, and Native Hawaiian or Other Pacific Islander male and female participants with cGVHD who have previously been treated with at least 2 prior lines of systemic therapy aged 12 years and above. The duration of participants participation will be up to 4 weeks for screening, treatment until clinically significant progression of disease, and 4 weeks of safet... Read More
Gender:
ALL
Ages:
12 years and above
Trial Updated:
06/16/2025
Locations: Nicklaus Children's Hospital - Miami - Southwest 62nd Avenue- Site Number : 129, Miami, Florida
Conditions: Chronic Graft Versus Host Disease
Voclosporin in Adolescent and Pediatric Subjects With Lupus Nephritis
Recruiting
The purpose of this study is to assess the efficacy and safety of voclosporin compared to placebo in achieving renal response following 24 weeks of therapy in adolescent and pediatric subjects with active lupus nephritis (LN).
Gender:
ALL
Ages:
Between 5 years and 17 years
Trial Updated:
06/16/2025
Locations: Nemours Children's Hospital, Orlando, Orlando, Florida
Conditions: Adolescent Lupus Nephritis, Pediatric Lupus Nephritis
A Study of Ruxolitinib and Duvelisib in People With Lymphoma
Recruiting
This study will test the safety of ruxolitinib, given at one dose that does not change, and duvelisib, given at different doses, to find out what effects, if any, the study treatment has on people with relapsed or refractory NK-cell or T-cell lymphoma. This study has three parts: dose escalation (Part 1), dose expansion (Part 2), and TFH/T-PLL cohort expansion (Part 3).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/16/2025
Locations: University of Miami (Data Collection Only), Miami, Florida
Conditions: T-cell Lymphomas, NK-Cell Lymphomas, T-cell Prolymphocytic Leukemia, T-cell Large Granular Lymphocyte Leukemia
A Study to Evaluate the Safety and Anti-cancer Activity of Loncastuximab Tesirine in Combination With Other Anti-cancer Agents in Participants With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (LOTIS-7)
Recruiting
The primary objective of this study is to characterize the safety and tolerability of loncastuximab tesirine in combination with polatuzumab vedotin, glofitamab, or mosunetuzumab, and to identify the maximum tolerated dose (MTD) and/or recommended dose for expansion (RDE) for the combinations.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/16/2025
Locations: Sylvester Comprehensive Cancer Center, Miami, Florida
Conditions: B-Cell Non-Hodgkin Lymphoma, Relapsed B-Cell Non-Hodgkin Lymphoma, Refractory B-Cell Non-Hodgkin Lymphoma
IL2 With Ipilimumab Followed by Nivolumab in Stage 3 or 4 Melanoma Patients
Recruiting
The purpose of this study is to find out if the administration of Interleukin-2 concurrently with ipilimumab followed by Nivolumab will result in improved anti-cancer activity and if it is effective for advanced melanoma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/16/2025
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Melanoma Stage III, Melanoma Stage IV, Inoperable Disease
Evolutionary Therapy for Rhabdomyosarcoma
Recruiting
This clinical trial will evaluate 4 different strategies of chemotherapy schedules in newly diagnosed participants with metastatic Fusion Positive (alveolar) Rhabdomyosarcoma. The participant and their physician will choose from: Arm A) a first strike therapy, Arm B) a first strike-second strike (maintenance) therapy, Arm C) an adaptively timed therapy, and Arm D) conventional chemotherapy.
Gender:
ALL
Ages:
All
Trial Updated:
06/16/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Rhabdomyosarcoma
Robotic-Assisted da Vinci System Prophylactic Nipple-Sparing Mastectomy
Recruiting
This study evaluates the safety and effectiveness of the da Vinci Surgical Systems in prophylactic Nipple Sparing Mastectomy procedures.
Gender:
FEMALE
Ages:
Between 18 years and 80 years
Trial Updated:
06/16/2025
Locations: Mayo Clinic Florida, Jacksonville, Florida
Conditions: Nipple Sparing Mastectomy
National Collaborative to Improve Care of Children With Complex Congenital Heart Disease
Recruiting
The purpose of this initiative is to improve care and outcomes for infants with HLHS by expanding the NPC-QIC national registry to gather clinical care process, outcome, and developmental data on infants with HLHS between diagnosis and 12 months of age, by improving the use of standards into everyday practice across pediatric cardiology centers, and by engaging parents as partners in the process.
Gender:
ALL
Ages:
15 months and below
Trial Updated:
06/16/2025
Locations: University of Florida-UF Health, Gainesville, Florida
Conditions: Hypoplastic Left Heart Syndrome (HLHS)
Initial Feasibility Study to Treat Borderline Resectable Pancreatic Cancer With a Planar LDR Source
Recruiting
Initial study to evaluate local control and the preferred method of attachment of the CivaSheet in the setting of suspected close or positive margins at the time of surgical tumor removal.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/16/2025
Locations: Tampa General Hospital, Tampa, Florida
Conditions: Pancreatic Cancer