Florida is currently home to 3821 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Supporting Health in Veterans With Heart Failure
Recruiting
This study will test the effectiveness of a culturally-sensitive, telephone-based, tailored problem-solving intervention to improve physical and mental health in Veterans with heart failure (HF). Veterans will be recruited from VA clinics throughout the United States. As a component of this study, Veterans will partner with a registered nurse for a 12-week telehealth program that includes 8 telephone sessions. Follow-up data will be collected at 3-months (post intervention) and 6-, 12-, and 18-m... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/08/2025
Locations: VA Clinic - Gainesville, Gainesville, Florida
Conditions: Heart Failure
HPV Multilevel Intervention Strategies Targeting Immunization in Community Settings (HPV MISTICS)
Recruiting
This intervention study will use parent-, provider-, and health center-level strategies to promote HPV vaccination among 11-17 year olds receiving care in 8 community health centers in Florida, will explore factors related to the intervention effect, and will explore implementation outcomes of the intervention.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/08/2025
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Human Papilloma Virus (HPV) Vaccine
A Study of DZD9008 Versus Platinum-Based Doublet Chemotherapy in Local Advanced or Metastatic Non-small Cell Lung Cancer (WU-KONG28)
Recruiting
This is a phase 3, open-label, randomized, multi-center study assessing the efficacy and safety of DZD9008 versus platinum-based doublet chemotherapy in participants with locally advanced or metastatic NSCLC with EGFR Exon20ins mutation, who are newly diagnosed or have not received prior systemic therapy in advanced stage. Primary objective of this study is to assess the efficacy of DZD9008 versus platinum-based doublet chemotherapy using by BICR-assessed PFS per RECIST 1.1 as primary endpoint.... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/08/2025
Locations: D&H Cancer Research Center, Margate, Florida
Conditions: Non-small Cell Lung Cancer
Accelerated Resolution Therapy for Early Maladaptive Grief
Recruiting
The purpose study is to test the effects of accelerated resolution therapy (ART) on pre-loss grief and prolonged grief disorder among older adult family caregivers (FCGs). Additionally, to better understand predictors of response to ART, and cognitive processes that occur among grieving individuals following ART.
Gender:
ALL
Ages:
60 years and above
Trial Updated:
05/08/2025
Locations: Suncoast Hospice, Clearwater, Florida
Conditions: Grief
Study of the Combination Dostarlimab With Niraparib In Patients With Penile Carcinoma
Recruiting
The purpose of the study is to evaluate the efficacy and safety of the combination of niraparib and dostarlimab in patients participants with advanced relapsed/refractory penile cancer.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
05/08/2025
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Penile Carcinoma
Women's Heart Attack Research Program: Stress Ancillary Study
Recruiting
The Women's HARP study is a multi-center study focusing on women with clinical presentation of myocardial infarction (MI). Women will complete stress questionnaires following presentation to the medical center with elevated cardiac enzymes and abnormal electrocardiograms (ECGs). 2 months following MI, participants will be screened for the Stress Ancillary Study and enrolled if an elevated level of perceived stress is reported. After completing baseline assessments, participants will be randomize... Read More
Gender:
FEMALE
Ages:
Between 21 years and 99 years
Trial Updated:
05/08/2025
Locations: Univeristy of Florida, Gainesville, Florida
Conditions: Myocardial Infarction
Non-Narcotic Pain Control After ACL Reconstruction
Recruiting
This is a double-blind randomized controlled trial of standard of care therapy, either oral ketorolac (experimental group) or oral oxycodone (control group) to demonstrate efficacy in reducing the percentage of narcotic doses taken and documenting the number of patients with no exposure to any narcotics (take zero oxycodone) after undergoing primary knee ACL reconstruction outpatient surgery.
Gender:
ALL
Ages:
Between 15 years and 55 years
Trial Updated:
05/07/2025
Locations: Cleveland Clinic Coral Springs, Coral Springs, Florida
Conditions: ACL - Anterior Cruciate Ligament Rupture, ACL Injuries
Rademikibart Add-on Treatment of an Acute COPD Exacerbation (Seabreeze STAT COPD)
Recruiting
This is a Phase 2, multicenter study in adult participants with an acute COPD exacerbation and type 2 inflammation
Gender:
ALL
Ages:
Between 40 years and 80 years
Trial Updated:
05/07/2025
Locations: Synergy Healthcare, Bradenton, Florida
Conditions: COPD Acute Exacerbation
Rademikibart Add-on Treatment of an Acute Asthma Exacerbation (Seabreeze STAT Asthma)
Recruiting
This is a Phase 2, randomized, multicenter study in adult and adolescent participants with asthma and type 2 inflammation
Gender:
ALL
Ages:
Between 12 years and 75 years
Trial Updated:
05/07/2025
Locations: Synergy Healthcare, Bradenton, Florida
Conditions: Asthma Acute
Leveraging Electronic Health Record Tools to Improve the Evidence-Based Treatment of Children Hospitalized With Bronchiolitis
Recruiting
The goal of this experimental study is to learn whether different types of best practice advisories (BPAs) that direct clinicians to reference clinical guidelines embedded in the electronic health record (EHR) increase the delivery of evidence-based care in children presenting to the hospital with bronchiolitis. The main questions it aims to answer are: * Do BPAs improve clinicians' delivery of guideline-concordant care in bronchiolitis? * Do interruptive BPAs improve guideline-concordant care... Read More
Gender:
ALL
Ages:
24 months and below
Trial Updated:
05/07/2025
Locations: Johns Hopkins All Children's Hospital, Saint Petersburg, Florida
Conditions: Bronchiolitis
DISCOVERY of Risk Factors for Type 2 Diabetes in Youth
Recruiting
The goal of the DISCOVERY study is to provide innovative critical information regarding the unique natural history of glycemic control, insulin sensitivity, and β-cell function, and their mechanistic determinates, in obese adolescents at risk for developing type 2 diabetes.
Gender:
ALL
Ages:
Between 9 years and 14 years
Trial Updated:
05/07/2025
Locations: Johns Hopkins All Children's Hospital, St. Petersburg, Florida
Conditions: Diabetes Mellitus Type 2, Childhood-Onset
Spinal Networks of Balance Learning and Retention in Older Adults
Recruiting
Age-related balance and walking issues increase fall risks, leading to injuries, higher healthcare costs, reduced quality of life, and increased morbidity/mortality rates. Preserving functional ability is a crucial public health priority, with the potential to reduce healthcare costs and enhance older adults' quality of life. Declines in balance and walking ability threaten independence. These declines are attributed to spinal network impairments and may be mitigated by targeted interventions ai... Read More
Gender:
ALL
Ages:
Between 65 years and 95 years
Trial Updated:
05/07/2025
Locations: Malcom Randall VA Medical Center Brain Rehabilitation Research Center, Gainesville, Florida
Conditions: Aging