Florida is currently home to 3749 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Study of PF-07248144 in Advanced or Metastatic Solid Tumors
Recruiting
This is an open-label, multi center study to evaluate safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of PF-07248144 and early signs of clinical efficacy of PF-07248144 as a single agent and in combination with either fulvestrant or letrozole + palbociclib or with PF-07220060 + fulvestrant
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/02/2025
Locations: Holy Cross Hospital, Fort Lauderdale, Florida
Conditions: Locally Advanced or Metastatic ER+ HER2- Breast Cancer, Locally Advanced or Metastatic Castration-resistant Prostate Cancer, Locally Advanced or Metastatic Non-small Cell Lung Cancer
Use of CBD in the Treatment of Anxiety
Recruiting
This study will examine the doses, safety, and test the preliminary efficacy of hemp-derived CBD product for improving anxiety symptoms and sleep disturbances among individuals with anxiety. A 4-week, randomized, double-blind, placebo-controlled trial will be conducted to determine the safety, tolerability, preliminary efficacy, and acceptability of 50 to 150 mg/day of CBD. The treatment period will consist of a two-week titration period followed by a 2- week maintenance period. In addition, the... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
01/31/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Anxiety, Generalized Anxiety Disorder, Sleep Problems
iCCaRE Consortium Pilot Project 1: Feasibility of a Point of Prostate Cancer Diagnosis Intervention for Newly Diagnosed Black Men
Recruiting
This study is being done to determine the acceptance and effectiveness of a virtual robot assistant model at a urology clinic.
Gender:
ALL
Ages:
80 years and below
Trial Updated:
01/31/2025
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Prostate Carcinoma
Sequential Therapies Modeled on Evolutionary Dynamics for Breast Cancer
Recruiting
The purpose of the study is to test a treatment strategy with currently approved drugs to see if it is practical to administer the available drugs in a new way that researchers hope could be more effective in treating metastatic breast cancer.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
01/31/2025
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Metastatic Breast Cancer
VOICE-Early Response to Vedolizumab and IL-23 Antagonists in Participants With Crohn's Disease: A Prospective Observational Study
Recruiting
The primary aim of this study is to explore the time course of response to Vedolizumab in participants with CD as measured by the Patient-Reported Outcomes Measurement Information System (PROMIS) Pain Interference-short form (SF), as well as other PROMIS domain SFs (fatigue, anxiety, depression, sleep disturbance, physical function, and ability to participate in social roles and activities); other PRO measures will also be assessed.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/31/2025
Locations: Digestive and Liver Center of Florida, Kissimmee, Florida
Conditions: Crohn's Disease
Dose Escalation Trial of Safety, Pharmacokinetic/Pharmacodynamic and Preliminary Clinical Activity of Briquilimab in Adult Patients with Chronic Spontaneous Urticaria (CSU)
Recruiting
This trial will be performed as a three-part dose escalating clinical trial where Parts 1 is open label and Parts 2 and 3 are randomized, double-blinded, and placebo-controlled. The trial is intended to determine the safety and tolerability and assess the preliminary efficacy of briquilimab in adult participants with chronic spontaneous urticaria (CSU), who remain symptomatic despite treatment with H1 antihistamines and omalizumab. Additionally, pharmacokinetic (PK) properties of briquilimab, a... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/31/2025
Locations: Site 113, Miami, Florida
Conditions: Chronic Spontaneous Urticaria
Community Health Advocates for Motivating PAP Use in Our Neighborhoods.
Recruiting
The purpose of this research is to compare the impact of motivational enhancement therapy (MET), delivered by culturally congruent community health care workers (CHWs) versus usual care patients with previously untreated moderate-to-severe obstructive sleep apnea (OSA) on adherence to positive airway pressure (PAP) therapy.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
01/31/2025
Locations: University of Miami, Miami, Florida
Conditions: Obstructive Sleep Apnea
Senior Adult Hepatobiliary Prehab Study
Recruiting
The purpose of the study is to evaluate an exercise program for individuals with hepatobiliary cancer planning for surgery.
Gender:
ALL
Ages:
65 years and above
Trial Updated:
01/31/2025
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Hepatobiliary Cancer, Cholangiocarcinoma, Liver Metastases
The Potential of Kava in Enabling Tobacco Cessation - Its Holistic Effects in Managing Stress and Insomnia Associated With Abstinence
Recruiting
This study will evaluate the compliance with a daily kava regimen among active smokers who have an intention to quit smoking. This study will also investigate whether kava use can facilitate tobacco cessation, reduce stress, and improve sleep.
Gender:
ALL
Ages:
Between 21 years and 99 years
Trial Updated:
01/31/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Smoking
A Study Assessing KB407 for the Treatment of Cystic Fibrosis
Recruiting
This study will evaluate safety and tolerability of ascending doses of nebulized KB407 in adults with cystic fibrosis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/31/2025
Locations: University of Florida, Gainesville, Gainesville, Florida
Conditions: Cystic Fibrosis
Study of PIT565 in Relapsed and/or Refractory B-cell Malignancies
Recruiting
This is an open-label, multicenter, phase I study, which primary objective is to characterize the safety and tolerability of PIT565 and to identify maximal tolerated doses (MTDs) and/or recommended doses (RDs), schedule and route of administration in relapsed and/or refractory B-cell Non-Hodgkin lymphoma (R/R B-NHL) and relapsed and/or refractory B-cell acute lymphoblastic leukemia (R/R B-ALL).
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
01/31/2025
Locations: University Of Miami, Miami, Florida
Conditions: B-cell Non-Hodgkin Lymphoma (B-NHL), B-cell Acute Lymphoblastic Leukemia (B-ALL)
Efficacy of Atenativ in Patients with Congenital Antithrombin Deficiency Undergoing Surgery or Delivery
Recruiting
Assess the incidence of the composite of thrombotic events (TEs) and thromboembolic events (TEEs) in patients with congenital antithrombin deficiency under cover of Atenativ for surgical procedures or parturition.
Gender:
ALL
Ages:
Between 12 years and 80 years
Trial Updated:
01/31/2025
Locations: University of Miami, Miami, Florida
Conditions: Congenital Antithrombin Deficiency