Florida is currently home to 3838 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
International Pediatric Adrenocortical Tumor Registry
Recruiting
This study aims to collect demographic and medical information including detailed family history of cancer of children and adolescents with adrenocortical tumors in order to learn more about the clinical and epidemiological aspects, treatment modalities, and outcome of patients with this rare disease, worldwide. In addition, investigators at St. Jude Children's Research Hospital (SJCRH) plan to perform molecular studies of tumor cells aimed to clarify the role of the TP53 gene and other genetic... Read More
Gender:
ALL
Ages:
21 years and below
Trial Updated:
03/17/2025
Locations: All Children's Hospital/St. Petersburg Hospital, Saint Petersburg, Florida
Conditions: Adrenocortical Tumor
Tailored Anti-Inflammatory (A-I) Diet for Hispanics with Ulcerative Colitis (UC)
Recruiting
The purpose of this study is to test the effect of an anti-inflammatory diet that incorporates native foods of the Hispanics/Latino (H/L) diet on disease remission in H/L patients with Ulcerative Colitis (UC) and to identify biomarkers of response to dietary therapy.
Gender:
ALL
Ages:
Between 16 years and 75 years
Trial Updated:
03/14/2025
Locations: University of Miami Health System, Miami, Florida
Conditions: Ulcerative Colitis
Efficacy, Safety & Pharmacokinetic (PK) Study of HLD200 in Children Aged 4-5 Years with ADHD
Recruiting
This study will evaluate the efficacy, safety and pharmacokinetics of HLD200 (20 mg and 40 mg) in children aged 4 to 5 years with ADHD.
Gender:
ALL
Ages:
Between 4 years and 5 years
Trial Updated:
03/14/2025
Locations: HLD200-112 Study Site, Jacksonville, Florida
Conditions: Attention Deficit Hyperactivity Disorder
IHERO Study: Insurance, Health and Economic Resources Online for Emerging Adults with Type 1 Diabetes
Recruiting
This research study aims to test a financial and health insurance iHERO Toolkit for young adults with type1 diabetes. The iHERO Toolkit was developed over one year with the type 1 diabetes community, The Diabetes Link organization, and experts. Now, the investigators want to understand the impact of the iHERO Toolkit on diabetes self-management, financial stress, and health insurance literacy outcomes. The investigators are doing this study because it will help to better understand how to suppor... Read More
Gender:
ALL
Ages:
Between 18 years and 30 years
Trial Updated:
03/14/2025
Locations: University of Florida Diabetes Institute, Gainesville, Florida
Conditions: Type 1 Diabetes
Association Between Body Composition and Pain in Spinal Cord Injury
Recruiting
The purposes of the study are to quantify and compare relationships among acute changes in inflammatory markers and evoked pain sensitivity after a high-fat meal (HFM) challenge, compared to a moderate-fat meal challenge, and explore the influence of body composition on these responses, in individuals with chronic spinal cord injury
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
03/14/2025
Locations: University of Miami, Coral Gables, Florida
Conditions: Pain, Inflammatory Response
Two Biologically and Clinically Distinct Entities: Progressive Versus Stable Multiple Myeloma (MM) Precursor Conditions
Recruiting
The key aim of the study is to define the two biologically and clinically distinct entities: progressive versus stable myeloma precursor conditions.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/14/2025
Locations: University of Miami Hospitals, Miami, Florida
Conditions: Multiple Myeloma, Smoldering Multiple Myeloma, Monoclonal Gammopathy of Undetermined Significance
Phase 1/2 Clinical Trial of LY3884963 in Patients With Frontotemporal Dementia With Progranulin Mutations (FTD-GRN)
Recruiting
Study J4B-MC-OKAA is a Phase 1/2, multi-center, open-label ascending dose, first-in-human study that will evaluate the safety and effect of intra-cisternal LY3884963 administration on progranulin protein (PGRN) levels in patients with frontotemporal dementia with progranulin mutations (FTD-GRN). Two escalating dose (low dose and medium dose) cohorts are planned, as well as one bridging cohort which will allocate patients to receive either low or medium dose. The duration of the study is 5 years.... Read More
Gender:
ALL
Ages:
Between 30 years and 85 years
Trial Updated:
03/14/2025
Locations: k2 Medical Research-Maitland, Maitland, Florida
Conditions: Frontotemporal Dementia
Effect of Sirolimus on Molecular Alterations in Cerebral Aneurysms
Recruiting
The objective of this study is to explore the effects of Sirolimus on the underlying molecular alterations of cerebral aneurysms.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/14/2025
Locations: University of Miami, Miami, Florida
Conditions: Cerebral Aneurysm
The Safety and Efficacy of Alpha-1 Antitrypsin (AAT) for the Prevention of Graft-versus-host Disease (GVHD) in Patients Receiving Hematopoietic Cell Transplant
Recruiting
This study is a phase 2 / 3 prospective, double-blind, randomized, multicenter, placebo-controlled study for prevention of acute GVHD (aGVHD) in participants undergoing an unrelated (matched or single allele mismatched) or matched related allogeneic hematopoietic cell transplantation (HCT).
Gender:
ALL
Ages:
12 years and above
Trial Updated:
03/14/2025
Locations: Johns Hopkins Hospital, Saint Petersburg, Florida
Conditions: Acute-graft-versus-host Disease
DSC-MRI in Measuring rCBV for Early Response to Bevacizumab in Patients With Recurrent Glioblastoma
Recruiting
This phase II trial studies how well dynamic susceptibility contrast-enhanced magnetic resonance imaging (DSC-MRI) works in measuring relative cerebral blood volume (rCBV) for early response to bevacizumab in patients with glioblastoma that has come back. DSC-MRI may help evaluate changes in the blood vessels within the cancer to determine a patient?s response to treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/14/2025
Locations: Boca Raton Regional Hospital, Boca Raton, Florida
Conditions: Gliosarcoma, Recurrent Glioblastoma
Woodcasting Versus Thermoplast Splint in CMC Arthroplasty
Recruiting
This study is a prospective, randomized, nonblinded trial to evaluate patient preference in splints after having a carpometacarpal arthroplasty.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/13/2025
Locations: Florida Orthopaedic Institute, Tampa, Florida
Conditions: Carpometacarpal (CMC) Joint Arthritis
Ultrasound with Subharmonic Imaging and Subharmonic Aided Pressure Estimation (SHAPE) to Identify Portal Hypertension
Recruiting
This clinical trial tests the how well an ultrasound with subharmonic imaging and the subharmonic aided pressure estimation (SHAPE) technique works in identifying portal hypertension (PH). An ultrasound takes pictures of the inside of the body by bouncing sound waves off organs. PH is high blood pressure in the vein that carries blood to the liver from the stomach, small and large intestines, spleen, pancreas, and gallbladder. The complications associated with PH are clear only after severe live... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/13/2025
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Portal Hypertension