Florida is currently home to 3758 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Clinical Trial of Interventions to Support Family Surrogates of Critically Ill Patients
Recruiting
Hypotheses 1a and 1b: Compared to Supportive Conversation arm, the EMPOWER intervention will significantly decrease surrogate decision makers' symptoms of grief and Post Traumatic Stress Disorder (PTSD) (primary outcomes); and H1b. experiential avoidance, depression, regrets, and increases in patients' value-concordant care (secondary outcomes) at T1-T4. Hypothesis 2. Qualitative data will provide insights not captured by quantitative data. Hypothesis 3. Reductions in experiential avoidance wi... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/20/2024
Locations: University of Miami, Miami, Florida
Conditions: Grief, Trauma, Psychotherapy, Critical Care
Cultural Adaptation of a SSI for Youth Anxiety
Recruiting
The overarching objective of this protocol is to (1) adapt and (2) disseminate an evidence-based, brief (approximately 30 minute) single session intervention (SSI) to better reflect the cultural and linguistic diversity of Latin, Haitian, and Haitian-American individuals via a fully online platform.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/20/2024
Locations: University of Miami, Miami, Florida
Conditions: Anxiety Disorders
Study BT5528-100 in Patients With Advanced Solid Tumors Associated With EphA2 Expression
Recruiting
This clinical trial is evaluating a drug called BT5528 alone and in combination with nivolumab in participants with advanced solid tumors historically known for expression of EphA2. The main goals of this study are to: * Find the recommended dose(s) of BT5528 that can be given safely to participants alone and in combination with nivolumab * Learn more about the side effects of BT5528 * Learn about how effective BT5528 is for the treatment of ovarian cancer, urothelial/bladder cancer, lung cance... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/20/2024
Locations: Florida Cancer Specialists, Sarasota, Florida
Conditions: Advanced Solid Tumor Historically Known for High EphA2 Expression, Urothelial Cancer, Ovarian Cancer, Non-small Cell Lung Cancer, Head and Neck Cancer, Triple Negative Breast Cancer, Gastric/Upper Gastrointestinal Cancer
Upper Extremity Functional Electrical Stimulation (FES) for Restoration of Upper Extremity Function After Spinal Cord Injury (SCI)
Recruiting
The purpose of this research is to examine the effects that functional electrical stimulation (FES) therapy has on the way the arms, brain and spinal cord work. The study team wants to understand what recovery looks like in persons with a spinal cord injury (SCI) or peripheral nerve injury (PNI) using the MyndMove (MyndTec Inc., Ontario, Canada) therapy system. This type of therapy uses stimulation to help people with SCI and other neurological conditions to perform common tasks, work out, or st... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
11/19/2024
Locations: University of Miami - Miami Project to Cure Paralysis, Miami, Florida
Conditions: Spinal Cord Injuries, Peripheral Nerve Injuries
Investigating the Influence of Catheter Advancement Techniques on Needle Tip Movement During Intravenous Insertion
Recruiting
This proposed study aims to fill this gap by investigating whether needle tip movement during catheter advancement is affected by whether the individual performing the insertion pushes the catheter off the needle themselves or if it is done by another person.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/19/2024
Locations: UF Health Shands, Gainesville, Florida
Conditions: Health Care Utilization
Maturation of Arteriovenous Fistula With Automated Sonography Assessments Trial
Recruiting
This is a prospective, multi-center, two-arm, randomized trial to quantify the performance of the EchoMark®/EchoSure® System for AVF diagnostic ultrasound when used under a protocol of biweekly use for assessing fistula maturation and reducing time to Clinical Maturation.
Gender:
ALL
Ages:
Between 18 years and 84 years
Trial Updated:
11/19/2024
Locations: Orlando Health Heart and Vascular Institute, Orlando, Florida
Conditions: Diabetes, End Stage Renal Disease
Study of CYR-064 Versus Placebo in Patients.
Recruiting
Randomized, double-blinded, placebo-controlled trial to determine the safety and efficacy of CYR-064.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
11/19/2024
Locations: ENTAAFL, Boca Raton, Florida
Conditions: Hyposmia
Abatacept in Immune Checkpoint Inhibitor Myocarditis
Recruiting
The primary aim is to test whether abatacept, as compared to placebo, is associated with a reduction in major adverse cardiac events (MACE) among participants hospitalized with myocarditis secondary to an immune checkpoint inhibitor (ICI). The primary outcome, MACE, is a composite of first occurrence of cardiovascular death, non-fatal sudden cardiac arrest, cardiogenic shock, significant ventricular arrythmias, significant bradyarrythmias, or incident heart failure.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/19/2024
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Myocarditis Acute, Cancer
Study to Evaluate the Efficacy, Immunogenicity, and Safety of RSVpreF in Adults.
Recruiting
Efficacy Study: This randomized, double-blinded, placebo-controlled Phase 3 study is designed to assess the safety, immunogenicity, and efficacy of a single dose of RSVpreF in the prevention of LRTI-RSV in adults: * At a dose of 120µg. * In adults 60 years of age and older. * The duration of the study for each participant will be up to approximately 24 months. * The study will be conducted in the United States, Canada, Netherlands, Finland, Argentina, Japan and South Africa. Substudy A: This s... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
11/19/2024
Locations: JEM Research Institute, Atlantis, Florida
Conditions: Lower Respiratory Tract Illness
Taletrectinib Phase 2 Global Study in ROS1 Positive NSCLC
Recruiting
The main purpose of the study is to evaluate safety and efficacy of taletrectinib (also known as AB-106 or DS-6051b) monotherapy in the treatment of advanced NSCLC.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/19/2024
Locations: SCRI - Florida Cancer Specialists South, Fort Meyers, Florida
Conditions: Non Small Cell Lung Cancer
Real World Evidence with the Debritom+ TM Novel Micro Water Jet Technology At a Single Wound Center
Recruiting
Prospective, single-blinded, single-center, parallel group, randomized controlled trial (RCT) to assess rate and frequency of wound healing and associated financial savings, when using Medaxis debritom+ versus standard of care as a choice of debridement method, where both arms follow normal wound care practice in use of advanced wound care treatments.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/19/2024
Locations: MCR Health, Inc., Bradenton, Florida
Conditions: Diabetic Foot Ulcer, Venous Leg Ulcer, Surgical Wound Dehiscence, Traumatic Wounds
A Study of ZN-c3 in Women With Recurrent or Persistent Uterine Serous Carcinoma
Recruiting
This is a Phase 2 study to evaluate the clinical activity and safety of ZN-c3 (azenosertib) in adult women with recurrent or persistent uterine serous carcinoma (USC).
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
11/19/2024
Locations: Mount Sinai Medical Center, Miami Beach, Florida
Conditions: Uterine Serous Carcinoma