Florida is currently home to 3749 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Diaphragmatic Breathing for the Treatment of Bloating and Distension
Recruiting
The purpose of this study is to evaluate the efficacy of diaphragmatic breathing using the validated Mayo Bloating Questionnaire.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/12/2024
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Bloating
Clinical Utility of Management of Patients With Pulmonary Nodules Using the Percepta Nasal Swab Classifier
Recruiting
The goal of this observational study is to learn how a physician uses the results of the Percepta® Nasal Swab test to manage people with a newly identified pulmonary nodule. The main questions it aims to answer are: * Does the use of the Percepta Nasal swab test reduce the number of invasive procedures in people with a low-risk result and whose nodule is benign? * Does the use of the Percepta Nasal swab test decrease the time to treatment in people with a high-risk result and whose nodule is c... Read More
Gender:
ALL
Ages:
Between 29 years and 85 years
Trial Updated:
11/12/2024
Locations: Bay Pines VA HCS, Bay Pines, Florida
Conditions: Pulmonary Nodule, Solitary, Lung Cancer
A CCTA Imaging Trial to Evaluate the Effect of Obicetrapib/Ezetimibe on Coronary Plaque
Recruiting
This placebo-controlled, double-blind, randomized, Phase 3 study is being conducted in adult participants with high-risk atherosclerotic cardiovascular disease (ASCVD) who are not adequately controlled by their maximally tolerated lipid-modifying therapy, to assess the impact of the obicetrapib 10 mg + ezetimibe 10 mg FDC daily on coronary plaque and inflammation characteristics, evaluated using cardiovascular computed tomography angiography (CCTA).
Gender:
ALL
Ages:
45 years and above
Trial Updated:
11/12/2024
Locations: NGMR, Hialeah, Florida
Conditions: Lipidemia, Coronary Artery Disease, Plaque, Atherosclerotic
Families With Pride ("Familias Con Orgullo").
Recruiting
This study will evaluate the effects of a parenting intervention for Hispanic sexual minority youth in preventing/reducing drug use and depressive symptoms. It will also examine whether the intervention improves parent social support for the adolescent, parent acceptance, family functioning, and whether it reduces general stress and stress associated with being a Hispanic sexual minority.
Gender:
ALL
Ages:
Between 13 years and 19 years
Trial Updated:
11/12/2024
Locations: University of Miami, Coral Gables, Florida
Conditions: Depression, Drug Use
ADSTILADRIN Early Utilization and Outcomes in the Real World Setting
Recruiting
Multi-center, prospective non-interventional study to collect data on the early use of Adstiladrin in the US and Israel. Data will be collected from patients and prescribing physicians in a real-world setting
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/12/2024
Locations: Ferring Investigational Site, Gainesville, Florida
Conditions: Bladder Cancer
RRx-001 for Reducing Oral Mucositis in Patients Receiving Chemotherapy and Radiation for Head and Neck Cancer
Recruiting
The purpose of this study is to determine if RRx-001, which is added on to the cisplatin and radiation treatment, reduces the incidence of severe oral mucositis in patients with head and neck cancers. All patients in this study will receive 7 weeks of standard of care radiation therapy given with the chemotherapy agent, cisplatin. Patients will receive RRx-001 or placebo before start of standard of care treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/12/2024
Locations: Miami Cancer Institute, Miami, Florida
Conditions: Oral Mucositis
Dose Escalation Pilot Study to Evaluate the Safety of Alocyte for the Treatment of Facetogenic Back Pain
Recruiting
The purpose of this study is to see if the use of Alocyte (cord blood plasma plus mononucleic cells) will be safe, well tolerated, and whether it causes any side effects. The study will also examine if the use of the Investigational Product (IP) is able to reduce local inflammation or alleviate Facetogenic back pain
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/12/2024
Locations: The Center for Regenerative Medicine, North Miami, Florida
Conditions: Facet Joints; Degeneration, Back Pain, Facet Joint Pain
Incremental Hemodialysis: The TwoPlus Trial
Recruiting
This study is to prospectively compare clinical effectiveness between clinically- matched incremental hemodialysis and conventional hemodialysis in patients with incident kidney dysfunction requiring dialysis and residual kidney function. The study will enroll 350 patients on chronic hemodialysis and 140 caregivers of enrolled patients. Patients will be randomized in 1:1 ratio to either incremental start hemodialysis or conventional hemodialysis. Caregivers will be followed along with patients... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/12/2024
Locations: University of Florida, Jacksonville, Florida
Conditions: End-Stage Kidney Disease
Validating Gulf War Illness Blood Biomarkers
Recruiting
The investigators goals are to identify blood lipids/metabolites that correlate with cognitive decline in the presence of the APOE ε4 allele among veterans with GWI. To determine the effect of dietary, medical and biological factors that influence lipid and metabolites in blood from GW veterans. To identify blood lipid/metabolite profiles that correlate with bioenergetics deficits and glial activation in the brains of GWI. To validate blood biomarker signatures of GWI using APOE genotyping and b... Read More
Gender:
ALL
Ages:
35 years and above
Trial Updated:
11/12/2024
Locations: The Roskamp Institute, Sarasota, Florida
Conditions: Gulf War Syndrome, Gulf War Illness
Robotic Versus Open Ventral Hernia Repair
Recruiting
This is a randomized trial comparing open retromuscular ventral hernia repair to robotic retromuscular ventral hernia repair.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/12/2024
Locations: University of Florida Health, Gainesville, Florida
Conditions: Ventral Hernia
Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS
Recruiting
Evaluate the safety and tolerability of RMC-6236 in adults with specific RAS mutant advanced solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/12/2024
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Non-small Cell Lung Cancer (NSCLC), Colorectal Cancer (CRC), Pancreatic Ductal Adenocarcinoma (PDAC), Advanced Solid Tumors
Adenosine 2A Receptor Antagonism and AIH in ALS
Recruiting
The purpose of this research study is to determine the effects of a medication, istradefylline, in conjunction with breathing air with reduced oxygen for short periods of time (called acute intermittent hypoxia, or AIH), on breathing. This project will study breathing in people with amyotrophic lateral sclerosis (ALS) and unaffected, age-matched adults. Istradefylline is prescribed to increase movement in people with other neuromuscular conditions. A recently completed study found that people wi... Read More
Gender:
ALL
Ages:
Between 21 years and 80 years
Trial Updated:
11/12/2024
Locations: Clinical and Translational Research Building, Gainesville, Florida
Conditions: ALS