Florida is currently home to 3749 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Fasting ENHANCE Pilot Study
Recruiting
Grounded in the principles of geroscience, the proposed Fasting ENHANCE study will test whether a time restricted eating (TRE) regimen can improve cognitive function and other aspects of successful aging in a safe and sustainable manner in at risk overweight older adults. Specifically, this study will evaluate whether TRE can improve cognitive and physical function, as well as self-reported sleep, mood, and quality of life, in overweight, older adults (age \> 65 years) who are at high risk of co... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
10/23/2024
Locations: Clinical and Translational Research Building - Institute on Aging Suite, Gainesville, Florida
Conditions: Overweight and Obesity, Time Restricted Feeding, Alzheimer Disease
Kaneka IED Coil System for the Treatment of Wide Necked Ruptured and Unruptured Intracranial Aneurysms
Recruiting
This is a multi-center, prospective, propensity matched twin armed study conducted on 50 patients in the experimental arm followed for 18 months after intervention evaluating cost effectiveness, safety and efficacy of therapy.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
10/23/2024
Locations: Baptist Health Jacksonville, Jacksonville, Florida
Conditions: Intracranial Aneurysms, Wide Neck Intracranial Aneurysms
ctDNA-Guided Sunitinib And Regorafenib Therapy for GIST
Recruiting
The purpose of this research is to test if mutations (changes in DNA) in exons (segment of DNA or RNA containing information that has the instructions for making proteins) in the KIT gene can be used to predict the body's response to standard of care treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/23/2024
Locations: University of Miami, Miami, Florida
Conditions: Gastrointestinal Stromal Tumors
Safety and Efficacy of IMC-F106C as a Single Agent and in Combination With Checkpoint Inhibitors
Recruiting
Brenetafusp (IMC-F106C) is an immune-mobilizing monoclonal T cell receptor against cancer (ImmTAC ®) designed for the treatment of cancers positive for the tumor-associated antigen PRAME. This is a first-in-human trial designed to evaluate the safety and efficacy of brenetafusp in adult patients who have the appropriate HLA-A2 tissue marker and whose cancer is positive for PRAME.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/23/2024
Locations: Houston Lee Moffitt Cancer Center & Research Institute, Tampa, Florida
Conditions: Select Advanced Solid Tumors
Multi-site Confirmatory Efficacy Treatment Trial of Combat-related PTSD
Recruiting
The purpose of this study is to examine the benefits of combining repetitive Transcranial Magnetic Stimulation (rTMS) coupled with Cognitive Processing Therapy (CPT) in treating combat-related Posttraumatic Stress Disorder (PTSD) symptoms. The study will also examine change in depression, psychosocial functioning, and neurophysiological (i.e., electroencephalography and magnetic resonance images) measures.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
10/23/2024
Locations: Florida State University College of Medicine, Tallahassee, Florida
Conditions: Post Traumatic Stress Disorder
ALTO-100 in Bipolar Disorder with Depression (BD-D)
Recruiting
The purpose of this study is to assess antidepressant efficacy differences between ALTO-100 and placebo during the Double-Blind period in patients with bipolar disorder I or II with current major depressive episode, when used adjunctively to a mood stabilizer, related to patient characteristics. Additionally, safety, tolerability, and efficacy will be assessed in a subsequent open label treatment period.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
10/22/2024
Locations: Site 6067, Lauderhill, Florida
Conditions: Bipolar Disorder I or II with a Major Depressive Episode
PET Scan Study to Detect Prostate Cancer in Patients with Early PSA Recurrence
Recruiting
Flotufolastat F-18, sold under the brand name Posluma, is a radioactive diagnostic agent for use with positron emission tomography (PET) imaging for prostate cancer. The research is being done to study the capability of 18F-rhPSMA-7.3 (flotufolastat F-18) PET scan to detect prostate cancer when there are very low levels of Prostate-Specific Antigen (PSA) following previous radical prostatectomy surgery.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
10/22/2024
Locations: AdventHealth, Orlando, Florida
Conditions: Prostate Cancer (Post Prostatectomy)
CARE: Cancer Risk Perception and Women of Color
Recruiting
This study examines patient understanding of current and lifetime risk for breast cancer in women of color from diverse racial and ethnic backgrounds.
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
10/22/2024
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Breast Carcinoma
HIIT Following Breast Cancer Chemotherapy
Recruiting
Chemotherapy is an effective breast cancer treatment, which helped to increase the 5-year survival rate to approximately 95%. However, breast cancer survivors have a higher risk of cardiovascular disease (CVD) due to chemotherapy than adults without cancer. Cardiovascular rehabilitation can be an effective strategy to decrease the incidence of CVD and its risk factors in this population. The proposed study may help to examine the effect and durability of a novel high-intensity interval training... Read More
Gender:
FEMALE
Ages:
Between 18 years and 85 years
Trial Updated:
10/22/2024
Locations: Integrative Cardiovascular Physiology Laboratory, University of Florida, Gainesville, Florida
Conditions: Breast Cancer
Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer
Recruiting
The overarching objective of this project is to develop a pan-gynecologic cancer detection test using gynecologic (unique endometrial, cervical, and ovarian cancer) cancer-specific methylated DNA markers and high-risk human papilloma virus (HR-HPV) detected in vaginal fluid and/or plasma. This proposal defines Phase II MDM-based cancer detection studies in endometrial cancer (EC) and endometrial hyperplasia with atypia (AEH) in tampon-collected vaginal fluid and 2) ovarian cancer (OC) in plasma... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
10/22/2024
Locations: Mayo Clinic, Jacksonville, Florida
Conditions: Endometrial Cancer, Cervical Cancer, Atypical Endometrial Hyperplasia, Cervical Dysplasia, Adnexal Mass, Ovarian Cancer
CD4CAR for CD4+ Leukemia and Lymphoma
Recruiting
This study is designed as a single arm open label Phase I, 3x3, multicenter study of CD4-directed chimeric antigen receptor engineered T-cells (CD4CAR) in patients with relapsed or refractory T-cell leukemia and lymphoma. Specifically, the study will evaluate the safety and feasibility of CD4CAR T-cells. Funding Source - FDA OOPD
Gender:
ALL
Ages:
12 years and above
Trial Updated:
10/22/2024
Locations: University of Miami Sylvester Comprehensive Cancer Center, Miami, Florida
Conditions: T-cell Lymphoma, T-cell Leukemia
Efficacy of Education Versus Education Plus Prescribed Fluid Intake on Hydration Status in High School Athletes
Recruiting
Sports science testing by investigators at Gatorade Sports Science Institute has revealed that many athletes arrive at practice with a high urine specific gravity indicating they are hypohydrated. Though the data showed that most athletes don't lose more than 2% of their body weight in sweat during a training session, it is not known what the cumulative effects of living and training in a hot environment are over the course of a week. Previous research has indicated that prescribing fluid intake... Read More
Gender:
ALL
Ages:
Between 13 years and 19 years
Trial Updated:
10/21/2024
Locations: Gatorade Sports Science Institute (GSSI) at IMG Sports Academy, Bradenton, Florida
Conditions: Dehydration