Florida is currently home to 3751 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Lay-Delivered Behavioral Activation in Senior Centers
Recruiting
In response to large numbers of senior center clients who suffer untreated depression and the dearth of geriatric mental health providers, the investigators have simplified Behavioral Activation to be delivered by lay volunteers ("Do More, Feel Better"; DMFB). The focus of Behavioral Activation is to guide clients to reengage in daily pleasant and rewarding activities, and reduce depressive symptoms. If the investigators can show that the lay delivery model has positive impact in comparison to M... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
10/10/2024
Locations: Brandon Senior Center, Brandon, Florida
Conditions: Depression
Impella RP Flex with Smart Assist
Recruiting
To capture observational data of the Abiomed Impella RP Flex in a real-world setting.
Gender:
ALL
Ages:
All
Trial Updated:
10/09/2024
Locations: Advent Health Orlando, Orlando, Florida
Conditions: Right Ventricular (RV) Dysfunction
Physical Activity in Hidradenitis Suppurativa (HS)
Recruiting
The purpose of the study is to characterize the challenges to physical activity and exercise for HS patients and design an exercise program (EP) with evidence-based techniques and examine its outcome.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
10/09/2024
Locations: University of Miami, Miami, Florida
Conditions: Hidradenitis Suppurativa
Mono vs. Dual Therapy for Pediatric Pulmonary Arterial Hypertension
Recruiting
The investigators' central hypothesis is that early combination therapy with two PAH-specific oral therapies that have been shown to be well tolerated in the pediatric population, sildenafil and bosentan, will result in better World Health Organization (WHO) functional class at 12 months after initiation of PAH treatment than therapy with sildenafil alone.
Gender:
ALL
Ages:
Between 3 months and 18 years
Trial Updated:
10/09/2024
Locations: Johns Hopkins All Children's Hospital, Saint Petersburg, Florida
Conditions: Pediatric Pulmonary Hypertension
Post Approval Study (PAS) of the OPTIMIZER Smart and CCM Therapy
Recruiting
The OPTIMIZER Smart Post-Approval Study is a prospective, multi-center, non-randomized, single arm open label study of 620 subjects receiving an OPTIMIZER implant as standard of care. Patients to be included will have NYHA functional class III symptoms and a left ventricular ejection fraction of 25-45%
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/09/2024
Locations: Heart Rhythm Solutions, Davie, Florida
Conditions: Heart Failure
Azithromycin for Critical Asthma - Pediatrics
Recruiting
The CR-AZI Study will assess the immunomodulatory effects of Azithromycin for pediatric Critical Asthma.
Gender:
ALL
Ages:
Between 3 years and 17 years
Trial Updated:
10/08/2024
Locations: Johns Hopkins All Children's Hospital, Saint Petersburg, Florida
Conditions: Pediatric Asthma, Critical Illness
Safety, Tolerability, and Exploratory Efficacy Study of Intrathecally Administered Gene Therapy AMT-162 in Adult Participants with SOD1 Amyotrophic Lateral Sclerosis (SOD1-ALS)
Recruiting
This is the study of AMT-162 in Participants with SOD1-ALS and is designed to evaluate the safety, tolerability, and exploratory efficacy of intrathecally administered gene therapy AMT-162. AMT-162-001 is a Phase 1/2, multi-center, single ascending dose study.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/08/2024
Locations: Mayo Clinic Florida, Jacksonville, Florida
Conditions: Amyotrophic Lateral Sclerosis
Yoga Training and Retinal Vasculature
Recruiting
This study will compare the impact of a novel high-speed, cued yoga program to a standard yoga program on retinal microvasculature, cognition and neuromuscular function.
Gender:
ALL
Ages:
Between 60 years and 90 years
Trial Updated:
10/08/2024
Locations: Laboratory of Neruomuscular Research and Active Aging, Coral Gables, Florida
Conditions: Cognitive Change
A Study of a N, N-dimethyltryptamine (DMT) Analog (CYB004) in Participants with Generalized Anxiety Disorder (GAD)
Recruiting
The purpose of this proof-of-concept trial is to examine the safety, tolerability, and pharmacokinetics (PK), and preliminary clinical efficacy of CYB004 participants with GAD.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
10/08/2024
Locations: Innovative Clinical Research, Inc., Miami Lakes, Florida
Conditions: Generalized Anxiety Disorder
Utility of Multisensory Body-Representation in Spinal Cord Injury (SCI) With Pain
Recruiting
The purpose of this study is to investigate the effectiveness of bodily illusions combined with transcranial direct current stimulation (tDCS) on neuropathic pain symptoms and sensory functions in participants with spinal cord injury (SCI) and neuropathic pain.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
10/08/2024
Locations: University of Miami, Miami, Florida
Conditions: Spinal Cord Injuries, Neuropathic Pain
XmAb®20717 (Vudalimab) Alone or in Combination With Chemotherapy or Targeted Therapy in Patients With Metastatic Castration-Resistant Prostate Cancer
Recruiting
This Phase 2 study will investigate the safety and clinical activity of vudalimab (XmAb20717) alone or in combination with standard of care anticancer therapies in patients with metastatic castration-resistant prostate cancer (mCRPC) who have progressed on prior therapy.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
10/08/2024
Locations: Mayo Clinic, Jacksonville, Florida
Conditions: Metastatic Castration-Resistant Prostate Cancer
Proteinuria in Pre and Post Transplant
Recruiting
Patients with focal segmental glomerulosclerosis (FSGS) who progress rapidly to end stage renal disease (ESRD) are at highest risk for development of recurrence of proteinuria following kidney transplantation. This study will look at serum specimens pre and post transplant, as well as kidney transplant specimens pre and post reperfusion to identify where the defects has occured that results in recurrence of proteinuria in a given kidney transplant.
Gender:
ALL
Ages:
25 years and below
Trial Updated:
10/08/2024
Locations: University of Miami Miller School of Medicine Transplant Clinic, Miami, Florida
Conditions: Proteinuria