Florida is currently home to 3745 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Molecular Genetics Studies of Cancer Patients and Their Relatives
Recruiting
This trial studies the genetic and behavioral factors that may contribute to the development of specific cancers and how these factors may affect the outcome of the disease in patients with a history of cancer and their relatives.
Gender:
ALL
Ages:
All
Trial Updated:
10/01/2024
Locations: Lynn Regional Cancer Center - West, Boca Raton, Florida
Conditions: Malignant Neoplasm
Impact of Help-Seeking Behaviors on Allergic Rhinitis and Mental Health: A Longitudinal Study
Recruiting
This study explores how help-seeking behaviors for both emotional well-being and allergies impact the management of allergic rhinitis, asthma, and mental health symptoms, including anxiety and depression. The research involves a retrospective and longitudinal analysis of patients who sought treatment for allergic rhinitis and mental health concerns. The goal is to highlight the importance of integrating mental health care into allergy treatment plans to improve overall patient outcomes.
Gender:
ALL
Ages:
Between 4 years and 100 years
Trial Updated:
09/30/2024
Locations: QHSLab, West Palm Beach, Florida
Conditions: Mental Health Conditions, Allergic
A Phase II Study of ACR-368 and Low Dose Gemcitabine in R/M HNSCC
Recruiting
The purpose of the study is to determine the activity and safety of ACR-368 (prexasertib) in combination with gemcitabine in participants with Head and Neck Squamous Cell Carcinoma (HNSCC). Participants will receive the study drugs ACR-368 and a low dose of gemcitabine once every 2 weeks in 4-week cycles and will continue on treatment unless the disease deteriorates.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/30/2024
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Head and Neck Squamous Cell Carcinoma
A Study in Adults to Learn About Inherited Alpha-1 Antitrypsin Deficiency (AATD) and AATD Related Liver Problems
Recruiting
The main aim of this study is to learn about liver problems caused by the lack of alpha-1 antitrypsin (called Alpha-1 Antitrypsin Deficiency or AATD) in adults when not treated (this is called the natural history of a condition) over 5 years. Other aims are to learn what can predict the AATD-liver condition starting and getting better or worse, describe how this condition is currently being diagnosed and watched in normal hospital care, and describe how the AATD also affects and adult's lung fun... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/30/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Alpha1-Antitrypsin Deficiency
Understanding and Treating Traumatic Brain Injury (TBI) Associated Photophobia With Botulinum Toxin Type A (BoNT-A)
Recruiting
The purpose of this research is to understand and treat Traumatic Brain Injury (TBI) associated photophobia (light sensitivity) and its impact on visual function.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/30/2024
Locations: University of Miami, Miami, Florida
Conditions: Traumatic Brain Injury
Nerve Protection Evaluation: Revision Cubital Tunnel Syndrome Decompression
Recruiting
This single-cohort, prospective case series is designed to evaluate and characterize the use of Axoguard HA+ Nerve Protector™ to protect the ulnar nerve in a first revision cubital tunnel decompression procedure. Data on the primary cubital tunnel syndrome decompression, first revision decompression utilizing Axoguard HA+ Nerve Protector, participant-reported pain, motor and sensory functional outcomes, quality of life (QoL) outcomes, and recurrence/revision will be collected. This case series w... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/30/2024
Locations: Foundation for Orthopaedic Research and Education (Florida Orthopaedic Institute), Tampa, Florida
Conditions: Recurrent Cubital Tunnel Syndrome, Recalcitrant Cubital Tunnel Syndrome
Effect of Azeliragon Combined With Stereotactic Radiation Therapy in Patients With Brain Metastases
Recruiting
To determine the safety and efficacy of using the drug azeliragon combined with stereotactic radiosurgery. Specifically, to determine if this combination will lead to improved response in the brain (tumor shrinking in size) and overall tumor control (how long tumor remains controlled).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/30/2024
Locations: Miami Cancer Institute at Baptist Health, Inc., Miami, Florida
Conditions: Cancer, Metastasis, Metastatic Cancer, Brain Metastases, Brain Metastases, Adult
Feasibility of a Smartphone Application for Asthma Self-management
Recruiting
The primary goal of this project is to determine the feasibility, acceptability, and adherence of a smartphone application for improving asthma self-management in a pilot randomized controlled trial (RCT). The app is specifically designed to appeal to adolescents. Adolescents with persistent asthma will be randomized to receive: 1) standard-of-care or 2) the self-management app in addition to standard-of-care. Feasibility will be assessed by the ability to recruit and retain subjects, technical... Read More
Gender:
ALL
Ages:
Between 12 years and 17 years
Trial Updated:
09/30/2024
Locations: University of South Florida, Tampa, Florida
Conditions: Asthma Chronic
Investigating the Genetic and Phenotypic Presentation of Ataxia and Nucleotide Repeat Diseases
Recruiting
The purpose of this study is to create a repository for cerebellar ataxia and nucleotide repeat diseases in order to fully investigate the genetic and phenotypic presentations of both.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/30/2024
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Spinocerebellar Ataxias, Cerebellar Ataxia, Nucleotide Repeat Disease
The Effect of the Reflux Band™ Upper Esophageal Sphincter (UES) Assist Device on Reflux for Lung Transplant Recipients
Recruiting
A prospective, open label, study designed to assess the affect of the Reflux Band® UES Assist Device (Reflux Band) on reflux in patients that have undergone lung transplantation.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
09/30/2024
Locations: UF Health at the University of Florida, Gainesville, Florida
Conditions: Lung Transplant, GERD
Longitudinal Measurements of Flow in Cerebrospinal Fluid Shunts With a Wireless Thermal Anisotropy Measurement Device
Recruiting
This study evaluates the performance of a device for non-invasively assessing cerebrospinal fluid (CSF) shunt flow. Patients with an existing implanted shunt will wear the device to acquire longitudinal data.
Gender:
ALL
Ages:
Between 5 years and 80 years
Trial Updated:
09/27/2024
Locations: Tampa Marriott Water Street, Tampa, Florida
Conditions: Hydrocephalus
ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves
Recruiting
The objective of this study is to establish the safety and effectiveness of the Edwards SAPIEN X4 Transcatheter Heart Valve (THV) in subjects who are at high or greater risk with a failing aortic bioprosthetic valve.
Gender:
ALL
Ages:
All
Trial Updated:
09/27/2024
Locations: Naples Community Hospital Healthcare System, Naples, Florida
Conditions: Aortic Valve Insufficiency, Aortic Valve Stenosis