Florida is currently home to 3772 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
The Alpha-1 Foundation's and University of Florida's Alpha-1 Coded Testing (ACT) Study
Recruiting
The Alpha-1 Coded Testing (ACT) Study was established to study genetic testing and outcomes of individuals at risk for alpha-1 antitrypsin deficiency.
Gender:
ALL
Ages:
All
Trial Updated:
10/21/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Alpha-1 Antitrypsin Deficiency
Striving Towards EmPowerment and Medication Adherence R01
Recruiting
This is a study for Black women living with HIV to test a counseling program for Black women living with HIV. This participant may be a good fit if the participant is a Black woman, living with HIV, has a history of trauma, and is currently taking Antiretroviral Therapy (ART) medicines
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
10/19/2024
Locations: University of Miami, Miami, Florida
Conditions: Hiv, Mental Health Issue
Evaluating the Impact of Social and Genetic Factors on Outcomes in Adolescent and Young Adult Cancer Survivors
Recruiting
This study examines the impact of social and genetic factors on outcomes in adolescent and young adult (AYA) cancer survivors of Hodgkin or non-Hodgkin lymphoma. Compared to both older adult and childhood cancer patients, AYAs with cancer experience different diagnoses and specific biological, clinical, psychological and social factors that affect their risks for post-treatment morbidity and premature death. Collecting samples of blood samples and health and treatment information from cancer sur... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/18/2024
Locations: Holy Cross Hospital, Fort Lauderdale, Florida
Conditions: Hodgkin Lymphoma, Non-Hodgkin Lymphoma
Focused Radiation Versus Systemic Therapy for Kidney Cancer Patients With Limited Metastasis, SOAR Study
Recruiting
This phase III trial compares the effect of stero-ablative radiotherapy (SAbR) followed by standard of care systemic therapy, to standard of care systemic therapy alone, in patients with kidney cancer that has spread from where it first started (primary site) to a limited (2-5) number of places in the body (metastatic). Study doctors want to find out if this approach is better or worse than the usual approach for metastatic kidney cancer. The usual approach is defined as the care most people get... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/18/2024
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Metastatic Renal Cell Carcinoma, Stage IV Renal Cell Cancer AJCC v8
I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
Recruiting
The purpose of this study is to further advance the ability to practice personalized medicine by learning which new drug agents are most effective with which types of breast cancer tumors and by learning more about which early indicators of response (tumor analysis prior to surgery via magnetic resonance imaging (MRI) images along with tissue and blood samples) are predictors of treatment success.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/18/2024
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Breast Neoplasms, Breast Cancer, Breast Tumors, Angiosarcoma, TNBC - Triple-Negative Breast Cancer, HER2-positive Breast Cancer, HER2-negative Breast Cancer, Hormone Receptor Positive Tumor, Hormone Receptor Negative Tumor, Early-stage Breast Cancer, Locally Advanced Breast Cancer
Characterization of 18F-Fluciclovine PET Amino Acid Radiotracer in Resected Brain Metastasis
Recruiting
This study is for patients who have had surgery to remove brain metastasis and are planned to have stereotactic radiosurgery (SRS) after their brain surgery. It will be optional for patients to have a pre-surgery 18F-Fluciclovine PET/CT scan. The goal of the study is to determine whether a specific imaging agent, known as 18F-Fluciclovine, will help physicians evaluate the extent of surgery and determine if there is any visible tumor above what MRI alone can identify as well as improve the physi... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/17/2024
Locations: Miami Cancer Institute at Baptist Health South Florida, Miami, Florida
Conditions: Brain Metastases, Brain Cancer
Integration of Neurocognitive Biomarkers Into a Neuro-Oncology Clinic
Recruiting
This is prospective observational registry study that will assess 1) if the neurocognitive function app (Brainlab Cognition) can be used in a widespread neuro-oncology clinic setting and 2) if patient reported quality of life parameters can be obtained electronically and integrated into clinic.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/17/2024
Locations: Miami Cancer Institute, Miami, Florida
Conditions: Neurocognitive Disorders
MiSight 1 Day Post-Approval Study for Effectiveness and Visual Symptoms
Recruiting
The purpose of this post-approval study is to confirm the effectiveness of the MiSight 1 Day lens in clinical practices within the US and to assess the stability of the myopia reduction over one-year post-treatment.
Gender:
ALL
Ages:
Between 8 years and 12 years
Trial Updated:
10/17/2024
Locations: Nova Southeastern University (NSU) College of Optometry, Fort Lauderdale, Florida
Conditions: Myopia
Dose-Escalated Spine SbRT for Localized Metastasis to the Spinal Column
Recruiting
This study is being done to determine the feasibility and tolerability of a novel regimen of spine stereotactic radiosurgery (SSRS). SSRS delivers high doses of radiation to tumors of the spine using precision techniques. In standard medical care, conventional SSRS is delivered in only 1 or 2 treatments. When this treatment is delivered in only 1-2 treatments, a high dose is used which can increase the side effects of treatment. This study aims to test an alternative technique of delivering SSR... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/17/2024
Locations: Miami Cancer Institute at Baptist Health, Inc, Miami, Florida
Conditions: Spine Metastases, Metastasis Spine
Single and Multiple Ascending Dose Study in Healthy Participants and Participants With an Autoimmune Disease
Recruiting
The main purpose of this study is to to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), immunogenicity of LAD191 in healthy adults and in adults with an autoimmune disease.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
10/16/2024
Locations: Doral Medical Research, Miami, Florida
Conditions: Healthy Volunteers, Autoimmune Disease
Study of ORIC-114 in Patients with Advanced Solid Tumors Harboring an EGFR or HER2 Alteration
Recruiting
The purpose of this study is to establish the recommended Phase 2 dose (RP2D) and/or maximum tolerated dose (MTD), safety, pharmacokinetics (PK), pharmacodynamics (PD), and antitumor activity of ORIC-114 as a Single Agent or in Combination with Chemotherapy when administered to patients with advanced solid tumors harboring an EGFR or HER2 alteration.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/16/2024
Locations: Mayo Clinic, Jacksonville, Florida
Conditions: Solid Tumors
A Pilot Study to Assess the Safety, Tolerability, and Efficacy of Virtual Reality for the Treatment of Abdominal Pain in Quiescent Crohn's Disease
Recruiting
The purpose of this research is to see if patients with Crohn's disease (CD) and abdominal pain resulting in health-related quality of life deficits despite lack of evidence of active inflammation improve with the use of virtual reality (VR).
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
10/15/2024
Locations: Mayo Clinic Florida, Jacksonville, Florida
Conditions: Crohn's Disease, Abdominal Pain (AP)