Florida is currently home to 3829 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Miami, Tampa, Jacksonville and Orlando. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Multicenter Clinical Study of the SING-IMT in Patients with Late-stage AMD
Recruiting
The objective of this study is to determine the safety and effectiveness of the smaller incision, new generation (SING), implantable miniature telescope (IMT) in patients with moderate-severe central vision loss due to late-stage age-related macular degeneration (AMD).
Gender:
ALL
Ages:
65 years and above
Trial Updated:
11/27/2024
Locations: Sarasota Retina Institute, Sarasota, Florida
Conditions: Age-Related Macular Degeneration, Geographic Atrophy
Study of Complication Rates in Cataract Surgery Patients Treated With Combined Pre-operative NSAID, OMIDRIA, and Subconjunctival Triamcinolone Acetonide Compared With Peri-operative SOC
Recruiting
This is a multicenter, 2-arm, randomized, prospective study of patients slated for bilateral cataract extraction. One eye will be randomized to the Study Arm, and the fellow eye will be randomized to the Control Arm.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/26/2024
Locations: The Eye Associates - Venice, Venice, Florida
Conditions: Cataract
Analysis of RATS, VATS and Open Lung Resections After Neoadjuvant Chemo-immunotherapy in Patients Performed in Five Referred Centers
Recruiting
The study is a retrospective observational study. The study is designed to be multicentric and international and it will analyze medical records from selected patients diagnosed with locally advanced and resectable NSCLC who underwent lung resection by robotic, VATS and open approach after receiving neoadjuvant chemo-immunotherapy. There are no risks for the patients, as this is a retrospective data collection.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/26/2024
Locations: Baptist Health South Florida, Miami, Florida
Conditions: Non-Small Cell Lung Cancer
Effect of Watermelon on Gut and Cardiometabolic Health
Recruiting
The goal of this clinical trial is to evaluate the effect of daily fresh watermelon consumption for 6-weeks on gut health, including microbiome diversity, gut barrier and immune function in young adults with overweight and obesity. The main questions it aims to answer are: 1. Will consuming fresh watermelon daily for 6-weeks will improve intestinal barrier health and increase microbiome diversity such as an increased population of beneficial 'probiotic' bacteria when compared to control partici... Read More
Gender:
ALL
Ages:
Between 18 years and 30 years
Trial Updated:
11/26/2024
Locations: Florida State University - Gut Biome Lab, Tallahassee, Florida
Conditions: Obesity and Overweight, Dysbiosis
Metabolism and Sleep Apnea Treatment
Recruiting
The purpose of this research study is to see if obstructive sleep apnea (OSA) is associated with abnormalities in fat metabolism. Through this research study, the Investigator will evaluate how fat is metabolized in people with and without sleep apnea, what substances the fat tissue releases, and how these substances might change the way the body uses energy and sugar.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
11/26/2024
Locations: University of Miami, Miami, Florida
Conditions: Obstructive Sleep Apnea, Fat Disorder
A Study of Brepocitinib in Adults With Active, Non-Infectious, Non-Anterior Uveitis
Recruiting
The purpose of this study is to determine the safety and efficacy of brepocitinib in participants with active, non-anterior (intermediate, posterior, or pan) non-infectious uveitis (NIU).
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
11/25/2024
Locations: Clinical Trial Site, Fort Lauderdale, Florida
Conditions: Uveitis, Posterior, Uveitis, Intermediate, Uveitis
Long-Term Follow-up Study for Subjects With CHB Previously Treated With Imdusiran (AB729)
Recruiting
This is a long term follow-up study for chronic hepatitis B (CHB) subjects who have received imdusiran treatment in a prior clinical trial, stopped NA therapy during that trial, and remain off therapy. Subjects may enroll after completing the end of study visit (baseline visit within 12 weeks ± 1 week from the end of study \[EOS\] visit) from their imdusiran clinical trial (the "parent study"). No interventions will be performed in this study other than blood sample collections, review of curren... Read More
Gender:
ALL
Ages:
Between 20 years and 70 years
Trial Updated:
11/25/2024
Locations: University of Miami Miller School of Medicine, Miami, Florida
Conditions: Long Term Follow-up
Comparative Effectiveness of Mobile Health Smoking Cessation Approaches Among Underserved Patients in Primary Care
Recruiting
This study will evaluate the comparative effectiveness of three smoking cessation therapies: mobile health (mHealth) application iCanQuit, mHealth application iCanQuit + Motiv8, and the Florida quit line.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
11/25/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Tobacco Use Cessation
Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY
Recruiting
The overall goal of the DISCOVERY study is to better understand what factors contribute to changes in cognitive (i.e., thinking and memory) abilities in patients who experienced a stroke. The purpose of the study is to help doctors identify patients at risk for dementia (decline in memory, thinking and other mental abilities that significantly affects daily functioning) after their stroke so that future treatments may be developed to improve outcomes in stroke patients. For this study, a "stroke... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/25/2024
Locations: Mayo Clinic, Jacksonville, Florida
Conditions: Ischemic Stroke, Intracerebral Hemorrhage, Subarachnoid Hemorrhage, Dementia, Vascular, Mild Cognitive Impairment, Vascular Cognitive Impairment
Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma
Recruiting
Patients with a primary invasive melanoma are recommended to undergo excision of the primary lesion with a wide margin. There is evidence that less radical margins of excision may be just as safe. This is a randomised controlled trial of 1 cm versus 2 cm margin of excision of the primary lesion for adult patients with stage II primary invasive cutaneous melanomas (AJCC 8th edition) to determine differences in disease-free survival. A reduction in margins is expected to improve patient quality of... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/25/2024
Locations: University of Miami Sylvester Comprehensive Cancer Center at Aventura, Aventura, Florida
Conditions: Cutaneous Melanoma, Stage II
ProACT Post-Approval Study
Recruiting
The ProACT Post Approval Study is a 5-year prospective, open-label, multi-center study designed to evaluate the long-term incidence of urethral stricture and device erosion after ProACT implantation. In addition, the study will evaluate whether treatment with ProACT affects clinical outcomes after subsequent SUI therapies.
Gender:
MALE
Ages:
50 years and above
Trial Updated:
11/25/2024
Locations: University of Florida, Gainesville, Florida
Conditions: Stress Urinary Incontinence
Substance Use Treatment and Its Role in Supporting Social Cognition
Recruiting
This study aims to assess changes in empathy levels before and after residential treatment among individuals with substance use disorders.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/24/2024
Locations: Recovery Unplugged, Ft Lauderdale, Florida
Conditions: Substance Use, Empathy